PRO-SYS
- Product NDC
- 66975-720
- 11-digit product format
- 669750720
- Labeler code
- 66975
- Product ID
- 66975-720_4e53a23c-7977-632d-e063-6394a90a7ae6
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Sodium Fluoride
- Dosage form
- PASTE, DENTIFRICE
- Route
- DENTAL; ORAL
- Labeler
- Benco Dental
- Application
- M021
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2025-12-01
- Substance
- SODIUM FLUORIDE
- Active strength
- .11 g/100g
- NDC exclude flag
- No
- Listing certified through
- 2027-12-31
- Current FDA listing
- Yes
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- PRO-SYS
- Listing expiration
- 2027-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| SODIUM FLUORIDE | .11 g/100g |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| 8ZYQ1474W7 | Internal UNII lookup |
Harmonized RxCUI identifiers#
| Identifier | FDA.report destination |
|---|---|
| 416783 | Internal RxNorm lookup |
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| 4e539cb2-bcbd-95fc-e063-6294a90a2121 | Available on FDA.report |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 66975-720-01 | PRO-SYS | 113.4 g in 1 TUBE | PASTE, DENTIFRICE | 113.4 | 1 | |
| 66975-720-02 | PRO-SYS | 24 g in 1 TUBE | PASTE, DENTIFRICE | 24 | 1 |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Crest Pro-Health Gum Rescue Pro Soothing Clean | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 2f10c7ac-eb60-011e-e063-6394a90aca13 | 2026-01-08 | Warnings | M021 |
| Crest Deep Cleanse Cavity Defense | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 2e09cb3b-cf59-15b1-e063-6394a90a5c6a | 2026-01-08 | Warnings | M021 |
| Crest Pro-Health Maximum Cavity Protection | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 2eaeddc5-1559-9378-e063-6394a90a4ed7 | 2026-01-08 | Warnings | M021 |
| Crest 3D White Deep Stain Remover Dazzling Mint | SODIUM MONOFLUOROPHOSPHATE | The Procter & Gamble Manufacturing Company | 2f11e935-1711-5f1a-e063-6294a90af7d8 | 2026-01-08 | M021 | |
| HEB Gleaming White Fresh Mint | SODIUM FLUORIDE | HEB | 82491c8f-d2c2-2e4a-e053-2a91aa0a572f | 2026-01-08 | Warnings | M021 |
| Crest 3D White Brilliance Pro Ultra White | SODIUM MONOFLUOROPHOSPHATE | The Procter & Gamble Manufacturing Company | 338acdf2-548c-0614-e063-6294a90af635 | 2026-01-08 | M021 | |
| KIDS Crest Advanced Sugar and Bacteria Shield | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 2f371af0-a2d4-25a6-e063-6394a90a923d | 2026-01-08 | Warnings | M021 |
| Crest Pro-Health Gum Detoxify Plus | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 2f9e346e-d664-81d5-e063-6394a90a4525 | 2026-01-08 | Warnings | M021 |
| Crest 3D White Holiday Smile Deep Stain Remover and Whitestrips | SODIUM MONOFLUOROPHOSPHATE | The Procter & Gamble Manufacturing Company | 3c57d487-a3c7-b238-e063-6294a90aed81 | 2026-01-08 | M021 | |
| Crest Complete plus Scope Pro Advanced Freshness | SODIUM FLUORIDE | The Procter & Gamble Manufacturing Company | 325c3ab2-aaa2-a06f-e063-6294a90abefb | 2026-01-08 | Warnings | M021 |
| Crest Tartar Protection | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 5940711d-71b7-cb7d-e053-2a91aa0aef18 | 2026-01-08 | Warnings | M021 |
| Meijer Restore and Defend Sensitive | STANNOUS FLUORIDE | Meijer Distribution Inc | 82bdfdb5-39f2-8c09-e053-2991aa0a096c | 2026-01-08 | Warnings | M021 |
| Crest Strawberry | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 01f69824-e886-6e7b-e063-6294a90acf77 | 2026-01-08 | Warnings | M021 |
| Crest Bubblegum | SODIUM FLUORIDE | Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V. | 01f64874-6363-3dcc-e063-6394a90a2aec | 2026-01-08 | Warnings | M021 |
| Crest 3D White Fresh Mint | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 01f27a63-15f3-cee4-e063-6394a90afa3b | 2026-01-08 | Warnings | M021 |
| Crest Bubblegum | SODIUM FLUORIDE | Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V. | 01f618d7-be07-18c3-e063-6294a90a2d97 | 2026-01-08 | Warnings | M021 |
| Crest Strawberry | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 01f35279-76ce-6027-e063-6294a90a8e34 | 2026-01-08 | Warnings | M021 |
| Crest Snowberry | STANNOUS FLUORIDE | The Procter & Gamble Manufacturing Company | 42ca1f06-3e7d-8fed-e063-6394a90afbff | 2026-01-08 | Warnings | M021 |
| Crest Strawberry | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 7d615c52-f9c9-4856-e053-2991aa0a7927 | 2026-01-08 | Warnings | M021 |
| Crest Fresh and White | SODIUM FLUORIDE | Procter & Gamble Manufactura, S. de R.L. de C.V. | 5a1bb1fb-12a5-5fd1-e053-2991aa0a628b | 2026-01-08 | Warnings | M021 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 416783 | sodium fluoride 0.24 % Toothpaste | PSN | 4e539cb2-bcbd-95fc-e063-6294a90a2121 | 1 |
| 416783 | sodium fluoride 0.0024 MG/MG Toothpaste | SCD | 4e539cb2-bcbd-95fc-e063-6294a90a2121 | 1 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.13 % ) Toothpaste | SY | 4e539cb2-bcbd-95fc-e063-6294a90a2121 | 1 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.14 % ) Toothpaste | SY | 4e539cb2-bcbd-95fc-e063-6294a90a2121 | 1 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.15 % ) Toothpaste | SY | 4e539cb2-bcbd-95fc-e063-6294a90a2121 | 1 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|
| 66975-720-01 | 66975072001 | 113.4 g in 1 TUBE (66975-720-01) | 113.4 g | 2025-12-01 | No | No | Current |
| 66975-720-02 | 66975072002 | 24 g in 1 TUBE (66975-720-02) | 24 g | 2025-12-01 | No | No | Current |