Norepinephrine bitartrate

Product NDC
67457-852
11-digit product format
674570852
Labeler code
67457
Product ID
67457-852_af3a6bd3-bbc9-43a9-a277-b55ae59d5097
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Norepinephrine bitartrate
Dosage form
INJECTION, SOLUTION, CONCENTRATE
Route
INTRAVENOUS
Labeler
Mylan Institutional LLC
Application
ANDA211242
Marketing category
ANDA
Marketing start
2018-10-15
Substance
NOREPINEPHRINE BITARTRATE
Active strength
1 mg/mL
Pharmacologic classes
Catecholamine [EPC], Catecholamines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211242-001NOREPINEPHRINE BITARTRATENOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211242-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-0487673890dc5c…
2021-03-12 10:30 UTC2021-03A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-045aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-048869cabd3fbd…
2020-11-12 02:37 UTC2020-11A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04c0c555d07b60…
2019-12-14 00:12 UTC2019-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-043f01610625f2…
2019-09-15 20:21 UTC2019-09A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04b00525d2431f…
2019-07-19 19:46 UTC2019-07A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A211242-001NOREPINEPHRINE BITARTRATEEQ 1MG BASE/MLINJECTABLE / INJECTIONAP2018-10-04cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A211242-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211242-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211242-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211242-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211242-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211242-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211242-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211242-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211242-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211242-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211242-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211242-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211242-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211242-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211242-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211242-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211242-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A211242-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A211242-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211242-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A211242-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A211242-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A211242-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A211242-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A211242-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A211242-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A211242-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211242-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211242-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211242-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211242-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211242-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A211242-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A211242-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A211242-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A211242-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A211242-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A211242-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A211242-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A211242-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Norepinephrine bitartrate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NOREPINEPHRINE BITARTRATE1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
IFY5PE3ZRWInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
242969Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
d3ea12e0-88cc-49b0-b06e-5199ecd6ca69Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2ab36713-99a4-1d04-c42f-907afc73b6f9Product name720260105
209a4db0-2639-413d-9ad3-274ad7be11f7Product name120230912
08ddeef6-6d79-428b-a00b-432b50fc2b32Product name120230831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
67457-852-00Norepinephrine bitartrate4 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION, CONCENTRATE44
67457-852-04Norepinephrine bitartrate10 in 1 CARTONINJECTION, SOLUTION, CONCENTRATE104

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
67457-852-00ML - Milliliter67457-852d9b628f3-8af7-4426-92b0-98a4aa653c4f12018-11-06
67457-852-04ML - Milliliter67457-852fe9fd43d-33a6-4976-b379-0b2cf64a651312018-11-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
67457-852NOREPINEPHRINE BITARTRATE INJECTION, SOLUTION, CONCENTRATE [MYLAN INSTITUTIONAL LLC]4Current NDC, Legacy NDC, 2 package rows20231129_d3ea12e0-88cc-49b0-b06e-5199ecd6ca69.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Norepinephrine bitartrateNOREPINEPHRINE BITARTRATEMylan Institutional LLCd3ea12e0-88cc-49b0-b06e-5199ecd6ca692021-10-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211242
application number: ANDA211242
ndc (product): 67457-852
Norepinephrine bitartrateNOREPINEPHRINE BITARTRATEMylan Institutional LLC7a4950ea-6369-4dd5-97be-df21a5a5055f2021-03-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211242
application number: ANDA211242

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
242969norepinephrine bitartrate 4 MG in 4 mL InjectionPSNd3ea12e0-88cc-49b0-b06e-5199ecd6ca694
2429694 ML norepinephrine 1 MG/ML InjectionSCDd3ea12e0-88cc-49b0-b06e-5199ecd6ca694
242969norepinephrine (as bitartrate) 4 MG per 4 ML InjectionSYd3ea12e0-88cc-49b0-b06e-5199ecd6ca694
242969norepinephrine 4 MG per 4 ML InjectionSYd3ea12e0-88cc-49b0-b06e-5199ecd6ca694

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
67457-852-00674570852004 mL in 1 VIAL, SINGLE-DOSE4 mlHistorical
67457-852-046745708520410 VIAL, SINGLE-DOSE in 1 CARTON (67457-852-04) / 4 mL in 1 VIAL, SINGLE-DOSE (67457-852-00) 2018-10-150000-00-00NoNoCurrent