Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz
- Product NDC
- 67751-217
- 11-digit product format
- 677510217
- Labeler code
- 67751
- Product ID
- 67751-217_2395eed2-0bab-a839-e063-6394a90aded6
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- chlorpheniramine maleate, acetaminophen, phenylephrine hydrochloride, dextromethorphan hydrobromide
- Dosage form
- TABLET, EFFERVESCENT
- Route
- ORAL
- Labeler
- Navajo Manufacturing Company Inc.
- Application
- M012
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2022-06-01
- Substance
- DEXTROMETHORPHAN HYDROBROMIDE; CHLORPHENIRAMINE MALEATE; PHENYLEPHRINE HYDROCHLORIDE; ACETAMINOPHEN
- Active strength
- 10; 2; 5; 250 mg/1; mg/1; mg/1; mg/1
- Pharmacologic classes
- Adrenergic alpha1-Agonists [MoA], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA], alpha-1 Adrenergic Agonist [EPC]
- NDC exclude flag
- No
- Listing certified through
- 2026-12-31
- Current FDA listing
- Yes
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz
- Listing expiration
- 2026-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| DEXTROMETHORPHAN HYDROBROMIDE | 10 mg/1 |
| CHLORPHENIRAMINE MALEATE | 2 mg/1 |
| PHENYLEPHRINE HYDROCHLORIDE | 5 mg/1 |
| ACETAMINOPHEN | 250 mg/1 |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| 9D2RTI9KYH | Internal UNII lookup |
| V1Q0O9OJ9Z | Internal UNII lookup |
| 04JA59TNSJ | Internal UNII lookup |
| 362O9ITL9D | Internal UNII lookup |
Harmonized RxCUI identifiers#
| Identifier | FDA.report destination |
|---|---|
| 1536477 | Internal RxNorm lookup |
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| f6068011-ad56-59b4-e053-2995a90ac016 | Available on FDA.report |
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| d17a97fa-387f-690e-d2be-0083ab044a03 | Product name | 3 | 20170725 |
| 0fdb98e2-b951-a1ce-5715-2b187ba500ef | Product name | 4 | 20170718 |
| c6fba691-a132-4ede-95c6-f8c6bd696636 | Product name | 1 | 20150902 |
| c0200ab5-4954-454e-9676-30b741b245bd | Product name | 1 | 20150730 |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 67751-217-01 | Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz | 1 in 1 CARTON | TABLET, EFFERVESCENT | 1 | 2 | |
| 67751-217-01 | Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz | 1 in 1 POUCH | TABLET, EFFERVESCENT | 1 | 2 | |
| 67751-217-02 | Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz | 2 in 1 POUCH | TABLET, EFFERVESCENT | 2 | 2 | |
| 67751-217-02 | Alka-Seltzer Plus Severe Cold and Flu PowerFast Fizz | 1 in 1 CARTON | TABLET, EFFERVESCENT | 1 | 2 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 67751-217 | ALKA-SELTZER PLUS SEVERE COLD AND FLU POWERFAST FIZZ (CHLORPHENIRAMINE MALEATE, ACETAMINOPHEN, PHENYLEPHRINE HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE) TABLET, EFFERVESCENT [NAVAJO MANUFACTURING COMPANY INC.] | 2 | Current NDC, 4 package rows | 20241004_f6068011-ad56-59b4-e053-2995a90ac016.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Target Dye Free Childrens Allergy Relief | DIPHENHYDRAMINE HYDROCHLORIDE | Target Corporation | 76299495-7259-4bbe-8393-7eabfe22715a | 2025-11-05 | Warnings | M012 |
| TARGET CHILDRENS DT AND NT COLD and COUGH | BROMPHENIRAMINE MALEATE,DEXTROMETHORPHAN HBR,PHENYLEPHRINE HCL,DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL | TARGET CORPORATION | 05ac2a40-5eee-4013-b55b-6e370a28b21c | 2025-11-05 | Warnings | M012 |
| TARGET CHILDRENs COLD and COUGH | BROMPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL | TARGET CORPORATION | eb912834-1b14-484d-90f7-a8deb52c0d4e | 2025-11-05 | Warnings | M012 |
| UP and UP Daytime Childrens Multi Symptom Cold | DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE | Target Corporation | a2d99bc8-7295-4922-acff-0cb02c91273c | 2025-11-05 | Warnings | M012 |
| Good Neighbor Pharmacy Medicated Chest Rub | CAMPHOR, MENTHOL, EUCALYPTUS OIL | AMERISOURCE BERGEN | c1843f1a-ae5b-0fdf-e053-2995a90aae38 | 2025-11-05 | Warnings | M012 |
| Daytime Cold and Flu | ACETAMINOPHEN DEXTROMETHORPHAN HBR PHENYLEPHRINE HCL | QUALITY CHOICE (Chain Drug Marketing Association) | 4754363d-e163-42e0-a65d-1c4bac24f6c9 | 2025-11-05 | Warnings | M012 |
| Day Time Cold and Flu | ACETAMINOPHEN DEXTROMETHORPHAN HBR PHENYLEPHRINE HCL | Safeway, Inc. | 76d62892-615d-4744-95aa-3be1207a0e57 | 2025-11-05 | Warnings | M012 |
| Tussin DM Cough and Chest Congestion | DEXTROMETHORPHAN HBR, GUAIFENESIN | Safeway, Inc. | 6fefff08-13b0-47eb-aa32-8d7e4deeae7b | 2025-11-05 | Warnings | M012 |
| Menthol Drops Freegells Extra Strong Eucalyptus 30ct | MENTHOL | R.L. ALBERT & SON, INC | 165a8efa-2b03-4329-99fa-3233f0af7d08 | 2025-11-04 | Warnings | M012 |
| Menthol Drops Freegells Extra Strong Honey Lemon 30ct | MENTHOL | R.L. ALBERT & SON, INC | f9ea46fc-0b04-444e-95fc-09aff7e7978a | 2025-11-04 | Warnings | M012 |
| QUALITY CHOICE Maximum Strength Nighttime Cold and Flu | ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE | Chain Drug Marketing Association, Inc. | 40413cdb-68ac-70e1-e063-6394a90a9217 | 2025-11-04 | Warnings | M012 |
| Tussin CF | DEXTROMETHORPHAN HBR GUAIFENESIN PHENYLEPHRINE HCL | WinCo Foods, LLC | 73fec783-1594-447b-b059-49ea9dbb5bee | 2025-11-04 | Warnings | M012 |
| Texaclear Fast Acting Allergy Relief | CHLOPHEDIANOL HYDROCHLORIDE, PYRILAMINE MALEATE | GM Pharmaceuticals, INC | 17a2f643-fa98-21ee-e054-00144ff88e88 | 2025-11-03 | Warnings | M012 |
| Cold plus Flu Severe | ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 3e618bc7-0f51-e586-e063-6294a90afe37 | 2025-11-03 | Warnings | M012 |
| Head Congestion plus Mucus PE | ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 3e61b5b3-ad15-01bf-e063-6394a90a6ec3 | 2025-11-03 | Warnings | M012 |
| Cold plus Head Congestion Severe | ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 409540c0-1bab-9969-e063-6394a90a47c1 | 2025-11-03 | Warnings | M012 |
| Sinus Severe | ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 3e60b340-bd60-9318-e063-6294a90ad079 | 2025-11-03 | Warnings | M012 |
| Sinus Pressure and Pain PE | ACETAMINOPHEN AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 3e60e32f-3e5f-b775-e063-6294a90a097d | 2025-11-03 | Warnings | M012 |
| Sinus and Headache | ACETAMINOPHEN AND PHENYLEPHRINE HYDROCHLORIDE | HYVEE INC | 3e614265-b35a-5d01-e063-6294a90aad85 | 2025-11-03 | Warnings | M012 |
| Allergy Relief | DIPHENHYDRAMINE HYDROCHLORIDE | HYVEE INC | 3e60b0ed-889d-0f17-e063-6394a90a4694 | 2025-11-03 | Warnings | M012 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1536477 | acetaminophen 250 MG / chlorpheniramine maleate 2 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG Effervescent Oral Tablet | PSN | f6068011-ad56-59b4-e053-2995a90ac016 | 2 |
| 1536477 | acetaminophen 250 MG / chlorpheniramine maleate 2 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Effervescent Oral Tablet | SCD | f6068011-ad56-59b4-e053-2995a90ac016 | 2 |
| 1536477 | APAP 250 MG / Chlorpheniramine Maleate 2 MG / Dextromethorphan Hydrobromide 10 MG / Phenylephrine Hydrochloride 5 MG Effervescent Oral Tablet | SY | f6068011-ad56-59b4-e053-2995a90ac016 | 2 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|
| 67751-217-01 | 67751021701 | 1 POUCH in 1 CARTON (67751-217-01) / 1 TABLET, EFFERVESCENT in 1 POUCH | 1 pouch | 2022-06-01 | No | No | Current |
| 67751-217-02 | 67751021702 | 1 POUCH in 1 CARTON (67751-217-02) / 2 TABLET, EFFERVESCENT in 1 POUCH | 1 pouch | 2022-06-01 | No | No | Current |