Tirofiban hydrochloride

Product NDC
68083-145
11-digit product format
680830145
Labeler code
68083
Product ID
68083-145_a206685a-4e0d-40a1-8f39-a4b2f660d7d7
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tirofiban
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Gland Pharma Limited
Application
ANDA206888
Marketing category
ANDA
Marketing start
2021-04-15
Substance
TIROFIBAN HYDROCHLORIDE
Active strength
12.5 mg/250mL
Pharmacologic classes
Decreased Platelet Aggregation [PE], Platelet Aggregation Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A206888-001TIROFIBAN HYDROCHLORIDETIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A206888-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-0831067a03dcf5…
2025-08-23 18:47 UTC2025-08A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-086a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-0803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-082680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-085bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-0879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-081e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-088072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-085c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-085d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-084b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-086a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-081c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-089b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-083f0d92c62455…
2023-05-13 08:27 UTC2023-05A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08053a50430f4f…
2023-01-26 05:58 UTC2023-01A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-083bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-083a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A206888-001TIROFIBAN HYDROCHLORIDEEQ 12.5MG BASE/250ML (EQ 0.05MG BASE/ML)SOLUTION / INTRAVENOUSAP2021-04-08a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A206888-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A206888-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206888-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A206888-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206888-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206888-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206888-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206888-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206888-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206888-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206888-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206888-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206888-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206888-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206888-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206888-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206888-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206888-001AP14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A206888-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206888-001AP1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206888-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206888-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206888-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206888-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206888-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A206888-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A206888-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A206888-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A206888-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A206888-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A206888-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A206888-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A206888-001AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A206888-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Tirofiban hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TIROFIBAN HYDROCHLORIDE12.5 mg/250mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6H925F8O5JInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1737471Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
fa3ac570-f9f6-474c-a920-bd0cf03045acAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b3502f65-b30c-cd90-0b5d-36be3bd715c1Product name320240507

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
68083-145-01Tirofiban hydrochloride1 in 1 CARTONINJECTION, SOLUTION17
68083-145-01Tirofiban hydrochloride250 mL in 1 CONTAINERINJECTION, SOLUTION2507

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
68083-145TIROFIBAN HYDROCHLORIDE (TIROFIBAN) INJECTION, SOLUTION [GLAND PHARMA LIMITED]7Current NDC, Legacy NDC, 2 package rows20210520_fa3ac570-f9f6-474c-a920-bd0cf03045ac.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Tirofiban HydrochlorideTIROFIBAN HYDROCHLORIDESagent Pharmaceuticals13ea7fb8-4b01-4286-9464-26c0b624bc3b2024-11-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206888
application number: ANDA206888
Tirofiban hydrochlorideTIROFIBANGland Pharma Limitedfa3ac570-f9f6-474c-a920-bd0cf03045ac2021-05-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206888
application number: ANDA206888
ndc (product): 68083-145

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1737471tirofiban 12.5 MG in 250 ML InjectionPSNfa3ac570-f9f6-474c-a920-bd0cf03045ac7
1737471250 ML tirofiban 0.05 MG/ML InjectionSCDfa3ac570-f9f6-474c-a920-bd0cf03045ac7
1737471tirofiban (as hydrochloride) 12.5 MG per 250 ML InjectionSYfa3ac570-f9f6-474c-a920-bd0cf03045ac7
1737471tirofiban 12.5 MG per 250 ML InjectionSYfa3ac570-f9f6-474c-a920-bd0cf03045ac7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
68083-145-01680830145011 CONTAINER in 1 CARTON (68083-145-01) / 250 mL in 1 CONTAINER1 container2021-04-150000-00-00NoNoCurrent