Difluprednate

Product NDC
69238-1380
11-digit product format
692381380
Labeler code
69238
Product ID
69238-1380_28d97e13-000b-4f82-b42e-206c923ab057
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Difluprednate ophthalmic
Dosage form
EMULSION
Route
OPHTHALMIC
Labeler
Amneal Pharmaceuticals NY LLC
Application
ANDA211526
Marketing category
ANDA
Marketing start
2021-11-18
Substance
DIFLUPREDNATE
Active strength
.5 mg/mL
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211526-001DIFLUPREDNATEDIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211526-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-174b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-176a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-171c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-173f0d92c62455…
2023-05-13 08:27 UTC2023-05A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17053a50430f4f…
2023-01-26 05:58 UTC2023-01A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-173bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-173a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211526-001DIFLUPREDNATE0.05%EMULSION / OPHTHALMICAB2021-11-17a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211526-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211526-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211526-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211526-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211526-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211526-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211526-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211526-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211526-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211526-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211526-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211526-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211526-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211526-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211526-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211526-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211526-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211526-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A211526-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211526-001AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211526-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211526-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211526-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211526-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211526-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A211526-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A211526-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A211526-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A211526-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A211526-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A211526-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A211526-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A211526-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211526-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Difluprednate
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIFLUPREDNATE.5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
S8A06QG2QEInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
804544Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3612ff2a-c4bf-4322-b5bc-e7b867575321Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
05bd5167-c8bb-b60b-f647-c2bfd6944eb3Product name520260107
6bd95106-a412-1dad-b9cc-4cb74bfb27ceProduct name220230315
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
290f523a-f9db-9774-b5a9-e1f908ac1782Product name120150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
c6b65c52-69c7-df49-550a-a50c137f6218Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69238-1380-3Difluprednate5 mL in 1 BOTTLEEMULSION57
69238-1380-3Difluprednate1 in 1 CARTONEMULSION17

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
69238-1380-3ML - Milliliter69238-1380123fd1c9-a89c-440f-bde5-3c4ba736effd12021-12-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
69238-1380DIFLUPREDNATE (DIFLUPREDNATE OPHTHALMIC) EMULSION [AMNEAL PHARMACEUTICALS NY LLC]6Current NDC, Legacy NDC, 2 package rows20240711_3612ff2a-c4bf-4322-b5bc-e7b867575321.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DifluprednateDIFLUPREDNATE OPHTHALMICAmneal Pharmaceuticals NY LLC3612ff2a-c4bf-4322-b5bc-e7b8675753212026-04-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211526
application number: ANDA211526
ndc (product): 69238-1380

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
804544difluprednate 0.05 % Ophthalmic EmulsionPSN3612ff2a-c4bf-4322-b5bc-e7b8675753217
804544difluprednate 0.5 MG/ML Ophthalmic SuspensionSCD3612ff2a-c4bf-4322-b5bc-e7b8675753217
804544difluprednate 0.05 % Ophthalmic EmulsionSY3612ff2a-c4bf-4322-b5bc-e7b8675753217

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
69238-1380-3692381380031 BOTTLE in 1 CARTON (69238-1380-3) / 5 mL in 1 BOTTLE1 bottle2021-11-180000-00-00NoNoCurrent