Head and Shoulders Apple Cider Vinegar 2in1

Product NDC: 69423-522
11-digit product format: 694230522
Labeler code: 69423
Product ID: 69423-522_46411d20-a5fe-3d6d-e063-6294a90ae80c
Type: HUMAN OTC DRUG
Nonproprietary name: Pyrithione Zinc
Dosage form: LOTION/SHAMPOO
Route: TOPICAL
Labeler: The Procter & Gamble Manufacturing Company
Application: M032
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-11-17
Substance: PYRITHIONE ZINC
Active strength: 1 g/100mL
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	69423-522	69423-522-12	D	Discontinued by firm		2026-10-05
excluded package	package	69423-522	69423-522-40	D	Discontinued by firm		2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 21 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	69423-522-12	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	69423-522-40	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	69423-522-12	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	69423-522-40	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	69423-522-12	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	69423-522-40	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	69423-522-12	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	69423-522-40	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	69423-522-12	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	69423-522-40	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	69423-522-12	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	69423-522-40	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	69423-522-12	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	69423-522-40	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	69423-522-12	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	69423-522-40	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	69423-522-12	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	69423-522-40	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	69423-522-12	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	69423-522-12	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	69423-522-12	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Head and Shoulders Apple Cider Vinegar 2in1
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PYRITHIONE ZINC	1 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R953O2RHZ5	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
209884	Internal RxNorm lookup
1043244	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
b698b310-a794-e7f3-e053-2a95a90a47c4	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
69423-522-12	2023-01-31	C162847	48780-1	f386c64a-0f01-0266-e053-dadaa90a7c1a	Head and Shoulders ® Apple Cider Vinegar 2in1
69423-522-40	2023-01-31	C162847	48780-1	f386c64a-0f01-0266-e053-dadaa90a7c1a	Head and Shoulders ® Apple Cider Vinegar 2in1

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
69423-522-12	Head and Shoulders Apple Cider Vinegar 2in1	1280 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1280	6
69423-522-37	Head and Shoulders Apple Cider Vinegar 2in1	370 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	370	6
69423-522-40	Head and Shoulders Apple Cider Vinegar 2in1	400 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	400	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
69423-522	HEAD AND SHOULDERS APPLE CIDER VINEGAR 2IN1 (PYRITHIONE ZINC) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	5	Current NDC, Legacy NDC, 3 package rows	20241128_b698b310-a794-e7f3-e053-2a95a90a47c4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 8 of 32 · 630 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Simply Clean Dandruff	PYRITHIONE ZINC	Old East Main Co.	643f571a-cf08-4f1f-9ad4-2bc68730ff57	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	Old East Main Co.	3c433aa9-9451-4820-8b58-632cf6d0c92a	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Old East Main Co.	3afc97ff-6a83-40af-9a61-26f00cfe4fa8	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Old East Main Co.	1d4966d1-02d9-4b70-acc2-88a8190f920c	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
Pyrithione zinc	PYRITHIONE ZINC	Old East Main Co.	f17154e2-1bcf-43f9-b201-e84d374a0591	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	Old East Main Co.	61bf3788-b1e8-4d7e-ac56-cf209ba39085	2026-03-02	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean Dandruff	PYRITHIONE ZINC	The Kroger Co.	835270e7-ba6a-46e8-a617-f5df1c69d411	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	The Kroger Co.	837d7a14-b312-4dce-a00a-623b50329378	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean	PYRITHIONE ZINC	The Kroger Co.	d442e1af-e31a-4de6-b358-52e08aedd7ee	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Clean Apple	PYRITHIONE ZINC	The Kroger Co.	00eb0594-cfa5-4fdb-aca8-650c10997924	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	Walmart Inc.	e4fd5d8b-a916-41c3-b05e-a32dd528f00f	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp	PYRITHIONS ZINC	Walmart Inc.	23ad86c0-5a75-4f52-8561-483708d415d6	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Everyday Clean 2 in 1	PYRITHIONE ZINC	Walmart Inc.	2bafcad7-1bb7-168e-e063-6394a90a0b9e	2026-02-27	Warnings, Adverse reactions	Exact identifier application number: M032
Paul Mitchell Dandruff	ZINC PYRITHIONE	John Paul Mitchell Systems	4bc02aa8-86b1-985e-e063-6294a90aa267	2026-02-26	Warnings	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	H E B	bdf0b3da-db37-4996-b5e5-23cf824d1d1f	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	PYRITHIONE ZINC	H E B	0927361e-a210-4e44-bbe7-fb68b240cf4f	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Care	PYRITHIONE ZINC	H E B	0410f6a6-6602-44fb-b223-586439938e19	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032
Dry Scalp Dandruff	PYRITHIONE ZINC	H E B	626933cb-9c84-4f37-943c-2a9bd21fcea5	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032
2 in 1 Dandruff	PYRITHIONE ZINC	H E B	75342eff-6bff-4fed-bd12-381edd2df681	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032
Dandruff	SELENIUM SULFIDE	H E B	182ca790-0713-412a-9111-c0cf40f20d02	2026-02-24	Warnings, Adverse reactions	Exact identifier application number: M032

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R953O2RHZ5	PYRITHIONE ZINC	13463-41-7	PYRITHIONE ZINC

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1043244	head & shoulders 1 % Medicated Shampoo	PSN	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Conditioner	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6
209884	zinc pyrithione 1 % Medicated Shampoo	SY	b698b310-a794-e7f3-e053-2a95a90a47c4	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
69423-522-12	69423052212	1280 mL in 1 BOTTLE, PUMP (69423-522-12)	1280 ml	2021-10-01	0000-00-00	No	No	Current
69423-522-37	69423052237	370 mL in 1 BOTTLE, PLASTIC (69423-522-37)	370 ml	2022-12-15		No	No	Current
69423-522-40	69423052240	400 mL in 1 BOTTLE, PLASTIC (69423-522-40)	400 ml	2020-11-17	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Head and Shoulders ® Apple Cider Vinegar 2in1	The Procter & Gamble Manufacturing Company	2025-12-18	HUMAN OTC DRUG LABEL	6