Narcan

Product NDC
69547-212
11-digit product format
695470212
Labeler code
69547
Product ID
69547-212_1d0be895-cd43-49f3-98d4-72a9c3088616
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
naloxone hydrochloride
Dosage form
SPRAY
Route
NASAL
Labeler
Emergent Devices Inc.
Application
NDA208411
Marketing category
NDA
Marketing start
2017-01-24
Marketing end
0000-00-00
Substance
NALOXONE HYDROCHLORIDE
Active strength
2 mg/.1mL
Pharmacologic classes
Opioid Antagonist [EPC], Opioid Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2023-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct69547-212DDiscontinued by firm2026-08-11
excluded packagepackage69547-21269547-212-04DDiscontinued by firm2026-08-11
excluded packagepackage69547-21269547-212-24DDiscontinued by firm2026-08-11

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208411-001NARCANNALOXONE HYDROCHLORIDE4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18
N208411-002NARCANNALOXONE HYDROCHLORIDE2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-1803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-182680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-185bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18d06236e962d9…
2024-10-29 15:01 UTC2024-10N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-1879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-181e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-188072bd15b7f6…
2024-05-31 18:47 UTC2024-05N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALABRLD, RS2015-11-185c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALABRLD, RS2015-11-185d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-002NARCAN2MG/SPRAYSPRAY, METERED / NASALRLD2017-01-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALABRLD, RS2015-11-184b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N208411-002NARCAN2MG/SPRAYSPRAY, METERED / NASALRLD2017-01-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-1874a2ff9319b5…
2019-12-13 00:20 UTC2019-12N208411-002NARCAN2MG/SPRAYSPRAY, METERED / NASALRLD2017-01-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALABRLD, RS2015-11-18bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**SPRAY, METERED / NASALRLD2017-01-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208411-001NARCAN4MG/SPRAYSPRAY, METERED / NASALRLD, RS2015-11-18782e0a99824c…
2021-12-28 21:50 UTC2021-12N208411-002NARCAN2MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**SPRAY, METERED / NASALRLD2017-01-24782e0a99824c…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208411-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208411-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N208411-001AB1bb7c543d1eb4…
2023-01-26 05:58 UTC2023-01N208411-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208411-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208411-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208411-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N208411-001AB1cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 5 · 178 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2025-08-23 18:47 UTC2025-08N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-30d06236e962d9…
2024-10-29 15:01 UTC2024-10N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-3079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-30301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-301e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208411-00294806442035-03-16U-1903Drug product, Delist requested2017-01-308072bd15b7f6…
2024-05-31 18:47 UTC2024-05N208411-00297072262035-03-16U-1903Drug product, Delist requested2017-07-188072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-001100859372035-03-16U-19032018-10-035c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00192112532035-03-16Drug product2015-12-165c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00194687472035-03-16U-1903Drug product2016-10-185c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00195611772035-03-16U-1903Drug product2017-02-075c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00196299652035-03-16U-1903Drug product2017-04-275c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00197758382035-03-16U-19032017-10-055c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00294806442035-03-16U-1903Drug product2017-01-305c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208411-00297072262035-03-16U-1903Drug product2017-07-185c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208411-001100859372035-03-16U-19032018-10-035d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00192112532035-03-16Drug product2015-12-165d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00194687472035-03-16U-1903Drug product2016-10-185d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00195611772035-03-16U-1903Drug product2017-02-075d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00196299652035-03-16U-1903Drug product2017-04-275d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00197758382035-03-16U-19032017-10-055d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00294806442035-03-16U-1903Drug product2017-01-305d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N208411-00297072262035-03-16U-1903Drug product2017-07-185d02ea3f76ae…

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
69547-212NARCAN (NALOXONE HYDROCHLORIDE) SPRAY NARCAN (NALOXONE HYDROCHLORIDE) SPRAY [EMERGENT DEVICES INC.]21Legacy NDC20221206_724df050-5332-4d0a-9a5f-17bf08a547e1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 8 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
NARCANNALOXONE HYDROCHLORIDE NASALSportpharm LLC3d43b2a2-9cc3-4c14-8ae7-fea4c83a7f922026-04-24WarningsExact identifier
application applno (NDA): 208411
application number: NDA208411
NARCANNALOXONE HYDROCHLORIDE NASALEmergent Devices Inc.a0ebc83d-2892-40de-bc0a-775ce90b30db2026-04-22WarningsExact identifier
application applno (NDA): 208411
application number: NDA208411
NarcanNALOXONE HYDROCHLORIDEEmergent Devices Inc.724df050-5332-4d0a-9a5f-17bf08a547e12025-12-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 208411
application number: NDA208411
Narcan Naloxone HCLNARCAN NALOXONE HCLHF Acquisition Co LLC, DBA HealthFirst11d770b8-b768-ba3d-e063-6394a90a61a62024-02-20WarningsExact identifier
application applno (NDA): 208411
application number: NDA208411
Naloxone HydrochlorideNALOXONE HYDROCHLORIDE NASALA-S Medication Solutions4517afa1-4b17-4a15-b91b-65b18bd0558f2023-11-24Warnings, Adverse reactionsExact identifier
application applno (NDA): 208411
application number: NDA208411
NARCAN NALOXONE HCINARCAN NALOXONE HCIHF Acquisition Co LLC, DBA HealthFirst784a0e98-c2d6-f845-e053-2991aa0ac4b42023-10-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 208411
application number: NDA208411
NARCANNALOXONE HYDROCHLORIDEA-S Medication Solutions139c30b9-5600-48f5-8610-0cacd27823982023-09-28Warnings, Adverse reactionsExact identifier
application applno (NDA): 208411
application number: NDA208411
NarcanNALOXONE HYDROCHLORIDEProficient Rx LP76b5a1ce-e601-457c-ab35-43533bba43942022-08-01Warnings, Adverse reactionsExact identifier
application applno (NDA): 208411
application number: NDA208411

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
69547-212-04695470212044 VIAL, SINGLE-DOSE in 1 PACKAGE (69547-212-04) > .1 mL in 1 VIAL, SINGLE-DOSE2017-01-240000-00-00NoNoCurrent
69547-212-246954702122424 VIAL, SINGLE-DOSE in 1 PACKAGE (69547-212-24) > .1 mL in 1 VIAL, SINGLE-DOSE2017-01-240000-00-00NoNoCurrent