Clozaril

Product NDC
69809-0127
11-digit product format
698090127
Labeler code
69809
Product ID
69809-0127_14601465-eda2-4063-b606-cb6cfcaaca3d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
clozapine
Dosage form
TABLET
Route
ORAL
Labeler
HLS Therapeutics (USA), Inc.
Application
NDA019758
Marketing category
NDA
Marketing start
2016-05-06
Substance
CLOZAPINE
Active strength
100 mg/1
Pharmacologic classes
Atypical Antipsychotic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019758-001CLOZARILCLOZAPINE25MGTABLET / ORALABRLD1989-09-26
N019758-002CLOZARILCLOZAPINE100MGTABLET / ORALABRLD, RS1989-09-26
N019758-003CLOZARILCLOZAPINE50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20
N019758-004CLOZARILCLOZAPINE200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N019758-001AB
N019758-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 168 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-26caaa826d4ba7…
2026-08-18 06:07:402026-07N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-26caaa826d4ba7…
2026-08-18 06:07:402026-07N019758-003CLOZARIL50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20caaa826d4ba7…
2026-08-18 06:07:402026-07N019758-004CLOZARIL200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019758-003CLOZARIL50MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019758-004CLOZARIL200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2019-05-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-001CLOZARIL25MGTABLET / ORALABRLD1989-09-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-002CLOZARIL100MGTABLET / ORALABRLD, RS1989-09-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-003CLOZARIL50MGTABLET / ORALRLD2019-05-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-004CLOZARIL200MGTABLET / ORALRLD2019-05-20d8e5a09893c0…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 144 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N019758-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019758-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019758-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019758-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019758-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019758-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019758-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019758-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019758-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019758-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019758-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019758-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019758-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019758-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019758-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019758-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019758-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019758-003AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019758-004AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019758-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019758-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019758-003AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019758-004AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019758-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019758-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019758-003AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019758-004AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019758-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019758-002AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019758-003AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019758-004AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019758-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019758-002AB15c6f7cd8ea54…

Additional Listing Data#

Finished product
Yes
Brand name base
Clozaril
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CLOZAPINE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
J60AR2IKICInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
104775Internal RxNorm lookup
104776Internal RxNorm lookup
197535Internal RxNorm lookup
197536Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
90876802-0e3a-44c9-9ff7-1754dfbe736aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
fde12e54-43fa-cc16-3015-4c000a7b8d3eProduct name520250812
0901063f-b37f-4bf1-8be6-1e2a469e57bcProduct name220180209
e01fb60f-a608-2c68-dfdd-23e6433ece68Product name520180209
7a7f58c4-be43-7e82-4dfc-128bbed4230aProduct name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69809-0127-5Clozaril100 in 1 BOTTLETABLET10021

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
69809-0127-5EA - Each69809-012780065849-bd3c-45fe-81e7-b6acd1b9c5be12017-07-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
69809-0127CLOZARIL (CLOZAPINE) TABLET [HLS THERAPEUTICS (USA), INC.]19Current NDC, Legacy NDC, 1 package rows20250327_90876802-0e3a-44c9-9ff7-1754dfbe736a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ClozarilCLOZAPINEHLS Therapeutics (USA), Inc.90876802-0e3a-44c9-9ff7-1754dfbe736a2025-06-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019758
application number: NDA019758
ndc (product): 69809-0127

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197535cloZAPine 100 MG Oral TabletPSN90876802-0e3a-44c9-9ff7-1754dfbe736a21
197536cloZAPine 25 MG Oral TabletPSN90876802-0e3a-44c9-9ff7-1754dfbe736a21
104776Clozaril 100 MG Oral TabletPSN90876802-0e3a-44c9-9ff7-1754dfbe736a21
104775Clozaril 25 MG Oral TabletPSN90876802-0e3a-44c9-9ff7-1754dfbe736a21
104776clozapine 100 MG Oral Tablet [Clozaril]SBD90876802-0e3a-44c9-9ff7-1754dfbe736a21
104775clozapine 25 MG Oral Tablet [Clozaril]SBD90876802-0e3a-44c9-9ff7-1754dfbe736a21
197535clozapine 100 MG Oral TabletSCD90876802-0e3a-44c9-9ff7-1754dfbe736a21
197536clozapine 25 MG Oral TabletSCD90876802-0e3a-44c9-9ff7-1754dfbe736a21
104776Clozaril 100 MG Oral TabletSY90876802-0e3a-44c9-9ff7-1754dfbe736a21
104775Clozaril 25 MG Oral TabletSY90876802-0e3a-44c9-9ff7-1754dfbe736a21

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
69809-0127-569809012705100 TABLET in 1 BOTTLE (69809-0127-5) 100 tablet2016-05-060000-00-00NoNoCurrent