Instaflex Extra Strength Pain Relief Cream

Product NDC: 70015-660
11-digit product format: 700150660
Labeler code: 70015
Product ID: 70015-660_5190500c-53c7-a68a-e063-6394a90a52a9
Type: HUMAN OTC DRUG
Nonproprietary name: Menthol, Methyl Salicylate
Dosage form: CREAM
Route: TOPICAL
Labeler: Healthy Directions, LLC
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2019-03-01
Substance: MENTHOL; METHYL SALICYLATE
Active strength: 25; 100 mg/g; mg/g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 45 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	70015-660-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	70015-660-04	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	70015-660-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	70015-660-04	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	70015-660-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	70015-660-04	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	70015-660-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	70015-660-04	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	70015-660-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	70015-660-04	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	70015-660-02	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	70015-660-04	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	70015-660-02	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	70015-660-04	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	70015-660-02	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	70015-660-04	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	70015-660-02	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	70015-660-04	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	70015-660-02	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	70015-660-04	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	70015-660-02	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	70015-660-04	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	70015-660-02	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	70015-660-04	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	70015-660-02	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	70015-660-04	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	70015-660-02	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	70015-660-04	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	70015-660-02	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	70015-660-04	`1332a3947898…`	`d4bfe170f9cd…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Instaflex Extra Strength Pain Relief Cream
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
MENTHOL	25 mg/g
METHYL SALICYLATE	100 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
L7T10EIP3A	Internal UNII lookup
LAV5U5022Y	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1148131	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
d058c64d-0e4f-45aa-8f52-804961b562e3	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
70015-660-02	2024-01-30	C162847	48780-1	1030e365-39cc-111a-e063-dadaa90a10e2	Instaflex Extra Strength Pain Relief Cream
70015-660-04	2024-01-30	C162847	48780-1	1030e365-39cc-111a-e063-dadaa90a10e2	Instaflex Extra Strength Pain Relief Cream

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
70015-660-02	Instaflex Extra Strength Pain Relief Cream	57 g in 1 TUBE	CREAM	57	2
70015-660-02	Instaflex Extra Strength Pain Relief Cream	1 in 1 CARTON	CREAM	1	2
70015-660-04	Instaflex Extra Strength Pain Relief Cream	1 in 1 CARTON	CREAM	1	2
70015-660-04	Instaflex Extra Strength Pain Relief Cream	113 g in 1 TUBE	CREAM	113	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
70015-660	INSTAFLEX EXTRA STRENGTH PAIN RELIEF CREAM (MENTHOL, METHYL SALICYLATE) CREAM [HEALTHY DIRECTIONS, LLC]	1	Current NDC, Legacy NDC, 4 package rows	20190301_d058c64d-0e4f-45aa-8f52-804961b562e3.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 112 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Chiggerex	BENZOCAINE	RANDOB LABS, LTD. DBA CROSSINGWELL CONSUMER HEALTH	5e5d84ab-f57f-448d-a4c1-ced38890eec2	2024-12-17	Warnings	Exact identifier application number: M017
DerMend Moisturizing Anti-Itch	PRAMOXINE HYDROCHLORIDE	Ferndale Laboratories, Inc.	14c7fb1c-a310-4b12-ab2e-7f1c0801995c	2024-12-17	Warnings	Exact identifier application number: M017
Hydrocortisone 1%	HYDROCORTISONE	Geri-Care Pharmaceuticals, Corp	fd67566a-1076-019d-e053-6394a90a415c	2024-12-17	Warnings	Exact identifier application number: M017
Extra Strength	MENTHOL AND METHYL SALICYLATE	NATURES FORMULAE HEALTH PRODUCTS LTD.	d919b50a-5de2-1830-e053-2a95a90ab88d	2024-12-17	Warnings	Exact identifier application number: M017
Cold and Heat Lidocaine Patch Plus Menthol	LIDOCAINE, MENTHOL	Walgreen Company	1f262473-3f3c-4f3f-b507-590d06ff69a9	2024-12-17	Warnings	Exact identifier application number: M017
Pain Relief Patches	CAMPHOR, MENTHOL, METHYL SALICYLATE	Walgreen Company	db8cf218-7544-4871-b1c3-a50a3d3e59f1	2024-12-17	Warnings	Exact identifier application number: M017
Albertsons Pain Relief Patch	LIDOCAINE	Safeway	dc2823bb-8586-daca-e053-2995a90a2af0	2024-12-17	Warnings	Exact identifier application number: M017
CAPSAICIN HEAT PATCHES BACK AND LARGE AREAS	CAPSAICIN	Walgreen Company	e77167ab-6cb8-4d5b-838c-b0acc05e3889	2024-12-17	Warnings	Exact identifier application number: M017
Hot and Cold Medicated Patch	MENTHOL	Walgreen Company	d9fc133d-ebaa-48f1-a6f9-62453970012b	2024-12-17	Warnings	Exact identifier application number: M017
PAIN RELIEF PATCHES	LIDOCAINE	Walgreen Company	204b96bc-af4e-4842-8b57-7b416feb4dd9	2024-12-17	Warnings	Exact identifier application number: M017
Lidocaine Dry	LIDOCAINE	CVS	bb7955fe-5113-1662-e053-2a95a90a85a1	2024-12-16	Warnings	Exact identifier application number: M017
HealthWise Medicated Original Body Powder 10 oz	MENTHOL	Veridian Healthcare	296b623a-14cd-0bca-e063-6394a90ac5ff	2024-12-16	Warnings	Exact identifier application number: M017
HealthWise Medicated Extra Body Powder 10 oz	MENTHOL	Veridian Healthcare	296c9a9c-e3db-59fe-e063-6294a90a0b62	2024-12-16	Warnings	Exact identifier application number: M017
Rite Aid Hot and Cold Roll On	MENTHOL 16%	Rite Aid	fc4b2635-280b-267f-e053-6294a90a5e22	2024-12-15	Warnings	Exact identifier application number: M017
Rite Aid Pain Relieving	BENZOCAINE 20%, MENTHOL 0.5%	Rite Aid	e2c09e85-be0a-4e6d-e053-2995a90ad756	2024-12-15	Warnings	Exact identifier application number: M017
Rugby Lidocaine	LIDOCAINE 4%	Rugby Laboratories	d94292f7-10fc-48bf-e053-2995a90a8472	2024-12-15	Warnings	Exact identifier application number: M017
Rite Aid Cortisone	HYDROCORTISONE 1%	Rite Aid	e27353b9-23b6-3801-e053-2a95a90a6045	2024-12-15	Warnings	Exact identifier application number: M017
Rite Aid Cooling Pain Relief	MENTHOL 10.5%	Rite Aid	e2225259-70ec-52de-e053-2a95a90a73f8	2024-12-15	Warnings	Exact identifier application number: M017
Rite Aid Rectal Care	LIDOCAINE 5%	Rite Aid	e283e462-96e8-04cf-e053-2a95a90a1d00	2024-12-15	Warnings	Exact identifier application number: M017
Rite Aid Anti-Itch	DIPHENHYDRAMINE HCL 2%	Rite Aid	e33898d8-1b8b-5c0b-e053-2995a90add08	2024-12-15	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
LAV5U5022Y	METHYL SALICYLATE	119-36-8	METHYL SALICYLATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1148131	menthol 2.5 % / methyl salicylate 10 % Topical Cream	PSN	d058c64d-0e4f-45aa-8f52-804961b562e3	2
1148131	menthol 25 MG/ML / methyl salicylate 100 MG/ML Topical Cream	SCD	d058c64d-0e4f-45aa-8f52-804961b562e3	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
70015-660-02	70015066002	1 TUBE in 1 CARTON (70015-660-02) / 57 g in 1 TUBE	1 tube	2019-03-01	0000-00-00	No	No	Current
70015-660-04	70015066004	1 TUBE in 1 CARTON (70015-660-04) / 113 g in 1 TUBE	1 tube	2019-03-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Instaflex Extra Strength Pain Relief Cream	Healthy Directions, LLC \| Pure Source, LLC	2026-05-11	HUMAN OTC DRUG LABEL	2