TIGLUTIK

Product NDC
70726-0303
11-digit product format
707260303
Labeler code
70726
Product ID
70726-0303_4746e22f-8ca7-9149-e063-6294a90aea8d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Riluzole
Dosage form
LIQUID
Route
ORAL
Labeler
EDW PHARMA, INC
Application
NDA209080
Marketing category
NDA
Marketing start
2018-09-21
Substance
RILUZOLE
Active strength
50 mg/10mL
Pharmacologic classes
Benzothiazole [EPC], Benzothiazoles [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N209080-001TIGLUTIK KITRILUZOLE50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N209080-001AB

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N209080-00187651502029-03-12U-2401Drug product2018-09-27

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALABRLD, RS2018-09-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-0587673890dc5c…
2021-03-12 10:30 UTC2021-03N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-053f01610625f2…
2019-09-15 20:21 UTC2019-09N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05b00525d2431f…
2019-07-19 19:46 UTC2019-07N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-053f0d92c62455…
2023-05-13 08:27 UTC2023-05N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05053a50430f4f…
2023-01-26 05:58 UTC2023-01N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N209080-001TIGLUTIK KIT50MG/10MLSUSPENSION / ORALRLD, RS2018-09-05e64feba35796…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N209080-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N209080-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N209080-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N209080-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N209080-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N209080-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N209080-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N209080-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N209080-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N209080-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N209080-001AB1d06236e962d9…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N209080-001AB1a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N209080-00187651502029-03-12U-2401Drug product2018-09-27caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N209080-00187651502029-03-12U-2401Drug product2018-09-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N209080-00187651502029-03-12U-2401Drug product2018-09-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08N209080-00187651502029-03-12U-2401Drug product2018-09-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N209080-00187651502029-03-12U-2401Drug product2018-09-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N209080-00187651502029-03-12U-2401Drug product2018-09-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N209080-00187651502029-03-12U-2401Drug product2018-09-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N209080-00187651502029-03-12U-2401Drug product2018-09-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N209080-00187651502029-03-12U-2401Drug product2018-09-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N209080-00187651502029-03-12U-2401Drug product2018-09-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N209080-00187651502029-03-12U-2401Drug product2018-09-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N209080-00187651502029-03-12U-2401Drug product2018-09-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N209080-00187651502029-03-12U-2401Drug product2018-09-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N209080-00187651502029-03-12U-2401Drug product2018-09-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05N209080-00187651502029-03-12U-2401Drug product2018-09-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N209080-00187651502029-03-12U-2401Drug product2018-09-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N209080-00187651502029-03-12U-2401Drug product2018-09-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N209080-00187651502029-03-12U-2401Drug product2018-09-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N209080-00187651502029-03-12U-2401Drug product2018-09-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03N209080-00187651502029-03-12U-2401Drug product2018-09-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N209080-00187651502029-03-12U-2401Drug product2018-09-27782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N209080-00187651502029-03-12U-2401Drug product2018-09-2787673890dc5c…
2021-03-12 10:30 UTC2021-03N209080-00187651502029-03-12U-2401Drug product2018-09-275aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N209080-00187651502029-03-12U-2401Drug product2018-09-278869cabd3fbd…
2020-11-12 02:37 UTC2020-11N209080-00187651502029-03-12U-2401Drug product2018-09-27c0c555d07b60…
2019-12-14 00:12 UTC2019-12N209080-00187651502029-03-12U-2401Drug product2018-09-273f01610625f2…
2019-09-15 20:21 UTC2019-09N209080-00187651502029-03-12U-2401Drug product2018-09-27b00525d2431f…
2019-07-19 19:46 UTC2019-07N209080-00187651502029-03-12U-2401Drug product2018-09-27ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N209080-00187651502029-03-12U-2401Drug product2018-09-276a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N209080-00187651502029-03-12U-2401Drug product2018-09-271c564ffb4f44…
2023-12-20 04:57 UTC2023-12N209080-00187651502029-03-12U-2401Drug product2018-09-27ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N209080-00187651502029-03-12U-2401Drug product2018-09-27a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N209080-00187651502029-03-12U-2401Drug product2018-09-279b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N209080-00187651502029-03-12U-2401Drug product2018-09-27a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N209080-00187651502029-03-12U-2401Drug product2018-09-273f0d92c62455…
2023-05-13 08:27 UTC2023-05N209080-00187651502029-03-12U-2401Drug product2018-09-27053a50430f4f…
2023-01-26 05:58 UTC2023-01N209080-00187651502029-03-12U-2401Drug product2018-09-273bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N209080-00187651502029-03-12U-2401Drug product2018-09-273a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N209080-00187651502029-03-12U-2401Drug product2018-09-27f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N209080-00187651502029-03-12U-2401Drug product2018-09-27e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
TIGLUTIK
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
RILUZOLE50 mg/10mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7LJ087RS6FInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2058147Internal RxNorm lookup
2059266Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
75d68f19-4208-109e-e053-2991aa0ac857Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
71bcb10f-c731-4369-817a-3db2209427adProduct name220250317
3e7d95d4-de41-5244-3ffc-380f6a049665Product name420200527
1d8c2f24-074a-49fc-a7ba-0d39b478c02fProduct name120200507

FDA-Initiated Inactive NDC Indexing#

Effective, Related label table
EffectiveRelated label
2023-08-31These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2023-08-31These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2023-01-30These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2023-01-30These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2020-03-12These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2020-03-12These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2020-01-31These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995
2020-01-31These highlights do not include all the information needed to use TIGLUTIK® safely and effectively. See full prescribing information for TIGLUTIK. TIGLUTIK (riluzole) oral suspension Initial U.S. Approval: 1995

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
70726-0303-1TIGLUTIK2 in 1 CARTONLIQUID221
70726-0303-2TIGLUTIK300 mL in 1 BOTTLE, PLASTICLIQUID30021

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
70726-0303-1ML - Milliliter70726-03038d41ee9e-6174-4dc1-8a7a-289efc7b762412018-10-11
70726-0303-2ML - Milliliter70726-03031482b307-24ba-439e-9a33-52682f5ecd6f12018-11-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
70726-0303TIGLUTIK (RILUZOLE) LIQUID [EDW PHARMA, INC]19Current NDC, Legacy NDC, 2 package rows20240210_75d68f19-4208-109e-e053-2991aa0ac857.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TIGLUTIKRILUZOLEItalfarmaco SPA20b7165a-eb4d-42a0-b2d8-16eff90a214e2026-07-29Exact identifier
application applno (NDA): 209080
application number: NDA209080
TIGLUTIKRILUZOLEEDW PHARMA, INC75d68f19-4208-109e-e053-2991aa0ac8572026-07-27Warnings, Adverse reactionsExact identifier
application applno (NDA): 209080
application number: NDA209080
ndc (product): 70726-0303

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2058147riluzole 50 MG in 10 mL Oral SuspensionPSN75d68f19-4208-109e-e053-2991aa0ac85721
2059266Tiglutik 50 MG in 10 mL Oral SuspensionPSN75d68f19-4208-109e-e053-2991aa0ac85721
2059266riluzole 5 MG/ML Oral Suspension [Tiglutik]SBD75d68f19-4208-109e-e053-2991aa0ac85721
2058147riluzole 5 MG/ML Oral SuspensionSCD75d68f19-4208-109e-e053-2991aa0ac85721
2058147riluzole 25 MG per 5 mL Oral SuspensionSY75d68f19-4208-109e-e053-2991aa0ac85721
2058147riluzole 50 MG per 10 mL Oral SuspensionSY75d68f19-4208-109e-e053-2991aa0ac85721
2059266Tiglutik 25 MG per 5 ML Oral SuspensionSY75d68f19-4208-109e-e053-2991aa0ac85721
2059266Tiglutik 5 MG/ML Oral SuspensionSY75d68f19-4208-109e-e053-2991aa0ac85721
2059266Tiglutik 50 MG per 10 ML Oral SuspensionSY75d68f19-4208-109e-e053-2991aa0ac85721

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
70726-0303-1707260303012 BOTTLE, PLASTIC in 1 CARTON (70726-0303-1) / 300 mL in 1 BOTTLE, PLASTIC (70726-0303-2) 2018-09-21NoNoCurrent
70726-0303-2707260303022 BOTTLE, PLASTIC in 1 CARTON (70726-0303-2) > 300 mL in 1 BOTTLE, PLASTIC (70726-0303-1) 2018-09-210000-00-00NoNoCurrent