Extra Strength No-Pain

Product NDC: 71309-001
11-digit product format: 713090001
Labeler code: 71309
Product ID: 71309-001_3371e8dc-ae55-9a65-e063-6394a90aeaac
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen
Dosage form: TABLET
Route: ORAL
Labeler: Safrel Pharmaceuticals, LLC.
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2017-07-31
Substance: ACETAMINOPHEN
Active strength: 500 mg/1
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 39 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	71309-001-40	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	71309-001-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	71309-001-40	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	71309-001-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	71309-001-40	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	71309-001-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	71309-001-40	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	71309-001-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	71309-001-40	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	71309-001-05	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	71309-001-40	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	71309-001-05	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	71309-001-40	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	71309-001-05	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	71309-001-40	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	71309-001-05	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	71309-001-40	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	71309-001-05	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	71309-001-40	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	71309-001-05	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	71309-001-40	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	71309-001-05	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	71309-001-40	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	71309-001-05	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	71309-001-40	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	71309-001-05	`1332a3947898…`	`d4bfe170f9cd…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Extra Strength No-Pain
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
198440	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
873f01dd-0701-5fd3-e053-2a95a90a6463	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
71309-001-05	2025-04-23	Acetaminophen Extra Strength 500 mg
71309-001-40	2025-04-23	Acetaminophen Extra Strength 500 mg
71309-001-05	2023-07-28	Acetaminophen Extra Strength 500 mg
71309-001-40	2023-07-28	Acetaminophen Extra Strength 500 mg

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
71309-001-05	Extra Strength No-Pain	500 in 1 BOTTLE	TABLET	500	6
71309-001-40	Extra Strength No-Pain	40 in 1 BOTTLE	TABLET	40	6
71309-001-40	Extra Strength No-Pain	1 in 1 CARTON	TABLET	1	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71309-001	EXTRA STRENGTH NO-PAIN (ACETAMINOPHEN) TABLET [SAFREL PHARMACEUTICALS, LLC.]	6	Current NDC, Legacy NDC, 3 package rows	20250425_873f01dd-0701-5fd3-e053-2a95a90a6463.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 13 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Meijer Effervescent Antacid and Pain Relief	ASPIRIN, ANHYDROUS CITRIC ACID, SODIUM BICARBONATE	Meijer Distribution Inc	7305972b-aa0f-4daa-e053-2991aa0adfd7	2026-05-11	Warnings	Exact identifier application number: M013
Genexa Kids Pain and Fever	ACETAMINOPHEN	Genexa, Inc.	091dd1e7-2484-cdbf-e063-6394a90a2189	2026-05-11	Warnings	Exact identifier application number: M013
Little Remedies Infant Fever/Pain Reliever	ACETAMINOPHEN	Medtech Products Inc.	af5c3b3b-079f-4ee6-a9a4-a13ee8cd99a5	2026-05-11	Warnings	Exact identifier application number: M013
Low Dose Aspirin	ASPIRIN	Wal-Mart Stores Inc	093e0458-9975-456f-8950-8273c8890b3c	2026-05-11	Warnings	Exact identifier application number: M013
Acetaminophen Extra Strength	ACETAMINOPHEN	CVS PHARMACY	afacdc0b-fb65-464e-91b8-e82ba7ecde44	2026-05-11	Warnings	Exact identifier application number: M013
CHILDRENS PAIN RELIEVER and FEVER REDUCER CHERRY	ACETAMINOPHEN	DeMoulas Market Basket	192f7c24-a4aa-4c05-8d64-5e7e0bf7a101	2026-05-09	Warnings	Exact identifier application number: M013
CHILDRENS PAIN RELIEVER and FEVER REDUCER GRAPE	ACETAMINOPHEN	DeMoulas Market Basket	0ff5c86e-d84b-42ad-b749-636ab2e3734e	2026-05-09	Warnings	Exact identifier application number: M013
Aspirin Regular Strength	ASPIRIN	Rugby Laboratories	939fce7e-55df-4dc5-916b-a533448e962f	2026-05-08	Warnings	Exact identifier application number: M013
Kids Pain and Fever	ACETAMINOPHEN	Genexa Inc.	f7e6e984-f0c3-ed40-e053-6294a90a89f7	2026-05-08	Warnings	Exact identifier application number: M013
Genexa Infants Pain and Fever	ACETAMINOPHEN	Genexa Inc.	c59cbf0e-1381-4dd2-e053-2a95a90a853a	2026-05-08	Warnings	Exact identifier application number: M013
Genexa Acetaminophen Extra Strength	ACETAMINOPHEN	Genexa Inc.	d6f968ca-719f-5a68-e053-2995a90a4afa	2026-05-08	Warnings	Exact identifier application number: M013
Kids Pain and Fever	ACETAMINOPHEN	Genexa Inc.	a7bd0b92-6f85-6175-e053-2995a90ab837	2026-05-08	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	Bryant Ranch Prepack	816b65d7-e53f-44c4-a418-074279d4b2af	2026-05-08	Warnings	Exact identifier application number: M013
Headache Relief	ACETAMINOPHEN, ASPIRIN, CAFFEINE	Amerisource Bergen	566dbd02-5e04-4461-8f5f-9fb58a42a375	2026-05-07	Warnings	Exact identifier application number: M013
Back and Body Extra Strength	ASPIRIN, CAFFEINE	DOLGENCORP, LLC	d4c0c81b-9176-47d0-a5e4-a584406078d9	2026-05-07	Warnings	Exact identifier application number: M013
Extra Strength Acetaminophen	ACETAMINOPHEN	Pinnacle RX LLC	513cf0e1-6874-9402-e063-6294a90aedc6	2026-05-07	Warnings	Exact identifier application number: M013
Infants Pain and Fever Cherry Flavor	ACETAMINOPHEN	Genexa Inc.	19215ea7-d55f-8d81-e063-6294a90a4924	2026-05-07	Warnings	Exact identifier application number: M013
up and up acetaminophen infants	ACETAMINOPHEN	Target Corporation	c1dd8330-fb6b-4d1f-9484-c199dc69214d	2026-05-07	Warnings	Exact identifier application number: M013
Extra Strength Aspirin	ASPIRIN	HHH Pharmaceuticals	90d457bb-79a7-4759-8ee7-6abffbe1e549	2026-05-06	Warnings	Exact identifier application number: M013
Aspirin 81mg Enteric Coated	ASPIRIN	HHH Pharmaceuticals	d81aec73-c7c1-4c52-80f6-fb0e32caf7aa	2026-05-06	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198440	acetaminophen 500 MG Oral Tablet	PSN	873f01dd-0701-5fd3-e053-2a95a90a6463	6
198440	acetaminophen 500 MG Oral Tablet	SCD	873f01dd-0701-5fd3-e053-2a95a90a6463	6
198440	APAP 500 MG Oral Tablet	SY	873f01dd-0701-5fd3-e053-2a95a90a6463	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
71309-001-05	71309000105	500 TABLET in 1 BOTTLE (71309-001-05)	500 tablet	2017-07-31	0000-00-00	No	No	Current
71309-001-40	71309000140	1 BOTTLE in 1 CARTON (71309-001-40) / 40 TABLET in 1 BOTTLE	1 bottle	2017-07-31	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Acetaminophen Extra Strength 500 mg	Safrel Pharmaceuticals, LLC.	2025-04-23	HUMAN OTC DRUG LABEL	6