Extra Strength No-Pain

Product NDC: 71309-001
11-digit product format: 713090001
Labeler code: 71309
Product ID: 71309-001_3371e8dc-ae55-9a65-e063-6394a90aeaac
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen
Dosage form: TABLET
Route: ORAL
Labeler: Safrel Pharmaceuticals, LLC.
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2017-07-31
Substance: ACETAMINOPHEN
Active strength: 500 mg/1
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 39 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	71309-001-40	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	71309-001-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	71309-001-40	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	71309-001-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	71309-001-40	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	71309-001-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	71309-001-40	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	71309-001-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	71309-001-40	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	71309-001-05	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	71309-001-40	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	71309-001-05	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	71309-001-40	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	71309-001-05	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	71309-001-40	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	71309-001-05	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	71309-001-40	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	71309-001-05	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	71309-001-40	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	71309-001-05	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded product	product		`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	71309-001-40	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-28 21:12 UTC · source 2024-05-28	excluded package	package	71309-001-05	`8af77b9d5b6f…`	`d9bbb34c5368…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded product	product		`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	71309-001-40	`834df4deac94…`	`adcc014656a3…`
2024-05-15 03:39 UTC · source 2024-05-14	excluded package	package	71309-001-05	`834df4deac94…`	`adcc014656a3…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded product	product		`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	71309-001-40	`1332a3947898…`	`d4bfe170f9cd…`
2024-03-11 06:39 UTC · source 2024-03-08	excluded package	package	71309-001-05	`1332a3947898…`	`d4bfe170f9cd…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Extra Strength No-Pain
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
198440	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
873f01dd-0701-5fd3-e053-2a95a90a6463	Available on FDA.report

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
71309-001-05	2025-04-23	Acetaminophen Extra Strength 500 mg
71309-001-40	2025-04-23	Acetaminophen Extra Strength 500 mg
71309-001-05	2023-07-28	Acetaminophen Extra Strength 500 mg
71309-001-40	2023-07-28	Acetaminophen Extra Strength 500 mg

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
71309-001-05	Extra Strength No-Pain	500 in 1 BOTTLE	TABLET	500	6
71309-001-40	Extra Strength No-Pain	40 in 1 BOTTLE	TABLET	40	6
71309-001-40	Extra Strength No-Pain	1 in 1 CARTON	TABLET	1	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
71309-001	EXTRA STRENGTH NO-PAIN (ACETAMINOPHEN) TABLET [SAFREL PHARMACEUTICALS, LLC.]	6	Current NDC, Legacy NDC, 3 package rows	20250425_873f01dd-0701-5fd3-e053-2a95a90a6463.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 48 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Aspirin 81 mg	ASPIRIN	Asclemed USA, Inc.	878dab20-668b-4d7a-a5f8-794a587564d5	2025-02-13	Warnings	Exact identifier application number: M013
ACETAMINOPHEN	ACETAMINOPHEN	CVS HEALTH CORP	bbc48c9e-7eb8-2c67-e053-2a95a90a8552	2025-02-13	Warnings	Exact identifier application number: M013
Dye Free Infants Pain and Fever	ACETAMINOPHEN	CVS	1fde0f7c-4b5b-ae9c-e063-6394a90afa41	2025-02-13	Warnings	Exact identifier application number: M013
NOTTS - Extra Strength 500 mg	ACETAMINOPHEN	VIVUNT PHARMA LLC	e677f43d-b4ce-e5b0-e053-2a95a90ad67e	2025-02-12	Warnings	Exact identifier application number: M013
Acetaminophen, Aspirin, Caffeine	ACETAMINOPHEN, ASPIRIN, CAFFEINE	LEADER/ Cardinal Health 110, Inc.	b3773f02-02a9-33c8-e053-2995a90a2235	2025-02-11	Warnings	Exact identifier application number: M013
EXTRA STRENGTH ACETAMINOPHEN	ACETAMINOPHEN	TIME CAP LABORATORIES, INC.	c9f80d24-bd05-e1ce-e053-2995a90aa646	2025-02-10	Warnings	Exact identifier application number: M013
Low dose Aspirin	ASPIRIN 81 MG DELAYED RELEASE TABLETS	WALGREENS	c25c55aa-9932-0a55-e053-2a95a90a3d1e	2025-02-10	Warnings	Exact identifier application number: M013
AeroTab Pain Reliever	PAIN RELIEVER	Aero Healthcare	40e2b5ea-a8ea-f1c6-e063-6394a90a1e6f	2025-02-10	Warnings	Exact identifier application number: M013
Enteric Coated Aspirin Regular Strength	ASPIRIN	Time-Cap Labs, Inc	5fbd8bb3-46f9-4089-9a21-b6af97a06106	2025-02-08	Warnings	Exact identifier application number: M013
ACETAMINOPHEN	ACETAMINOPHEN	TIME CAP LABS INC	c193dbc0-cc80-4a7c-aa29-457a20edf835	2025-02-08	Warnings	Exact identifier application number: M013
Daytime Severe Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HBR	Genexa Inc.	22f23aeb-f874-6e54-e063-6394a90a9565	2025-02-07	Warnings	Exact identifier application number: M013
Pain Relief	ACETAMINOPHEN	BETTER LIVING BRANDS LLC.	f3008928-c555-64ad-e053-2995a90a7307	2025-02-05	Warnings	Exact identifier application number: M013
Aspirin 81mg	ASPIRIN	BETTER LIVING BRANDS LLC.	f300dfbc-7137-79d1-e053-2995a90a636e	2025-02-05	Warnings	Exact identifier application number: M013
Low dose aspirin 81mg	ASPIRIN	BETTER LIVING BRANDS LLC.	f300c30b-ab1a-a1b4-e053-2a95a90a1294	2025-02-05	Warnings	Exact identifier application number: M013
Pain Reliever PM	ACETAMINOPHEN, DIPHENHYDRAMINE HCL	Strategic Sourcing Services LLC	5d174187-cf89-41ff-9a64-10e0276daf17	2025-02-05	Warnings	Exact identifier application number: M013
good sense pain relief	ACETAMINOPHEN	Bryant Ranch Prepack	c226205d-7c3c-49af-b3e2-fc7b09ad7857	2025-02-05	Warnings	Exact identifier application number: M013
Dye Free Childrens Acetaminophen	ACETAMINOPHEN	PAI Holdings, LLC dba PAI Pharma	a69fca9d-c0a0-4321-bf03-5c8e99cc07cc	2025-02-04	Warnings	Exact identifier application number: M013
TENSION HEADACHE RELIEF	ACETAMINOPHEN-CAFFEINE	TARGET CORPORATION	8ed1679d-d3a1-11b1-e053-2995a90a61ad	2025-01-31	Warnings	Exact identifier application number: M013
ValuMeds Extra Strength Headache Relief	ACETAMINOPHEN, ASPIRIN, CAFFEINE	Cabinet Health P.B.C.	0f864e73-e4b8-4e23-8990-8439ac17bd58	2025-01-31	Warnings	Exact identifier application number: M013
Extra Strength Pain Reliever	ACETAMINOPHEN TABLETS 500 MG	WALGREENS	c25bfe92-0196-0489-e053-2995a90abea1	2025-01-30	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198440	acetaminophen 500 MG Oral Tablet	PSN	873f01dd-0701-5fd3-e053-2a95a90a6463	6
198440	acetaminophen 500 MG Oral Tablet	SCD	873f01dd-0701-5fd3-e053-2a95a90a6463	6
198440	APAP 500 MG Oral Tablet	SY	873f01dd-0701-5fd3-e053-2a95a90a6463	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
71309-001-05	71309000105	500 TABLET in 1 BOTTLE (71309-001-05)	500 tablet	2017-07-31	0000-00-00	No	No	Current
71309-001-40	71309000140	1 BOTTLE in 1 CARTON (71309-001-40) / 40 TABLET in 1 BOTTLE	1 bottle	2017-07-31	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Acetaminophen Extra Strength 500 mg	Safrel Pharmaceuticals, LLC.	2025-04-23	HUMAN OTC DRUG LABEL	6