Home NDC 71335-2485 Naproxen
Product NDC 71335-2485
11-digit product format 713352485
Labeler code 71335
Product ID 71335-2485_7f075beb-f2b7-40e2-a4f4-a220bf1a2ac7
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name Naproxen
Dosage form TABLET
Route ORAL
Labeler Bryant Ranch Prepack
Application ANDA078250
Marketing category ANDA
Marketing start 2007-07-01
Substance NAPROXEN
Active strength 500 mg/1
Pharmacologic classes Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 44 .
Orange Book products# Current product rows page 1 of 1 · 3 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date A078250-001 NAPROXEN NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 A078250-002 NAPROXEN NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 A078250-003 NAPROXEN NAPROXEN 500MG TABLET / ORAL AB 2007-03-28
Therapeutic equivalence codes# Current TE-code rows page 1 of 1 · 3 matching rows.
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 4 · 132 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-10-15 13:18:30 2026-09 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 c2088c7a36db…2026-10-15 13:18:30 2026-09 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 c2088c7a36db…2026-10-15 13:18:30 2026-09 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 c2088c7a36db…2026-09-14 22:38:34 2026-08 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 84e616aacf4f…2026-09-14 22:38:34 2026-08 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 84e616aacf4f…2026-09-14 22:38:34 2026-08 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 84e616aacf4f…2026-08-18 06:07:40 2026-07 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 caaa826d4ba7…2026-08-18 06:07:40 2026-07 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 caaa826d4ba7…2026-08-18 06:07:40 2026-07 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 d06236e962d9…2024-10-29 15:01 UTC 2024-10 A078250-002 NAPROXEN 375MG TABLET / ORAL AB 2007-03-28 d06236e962d9…2024-10-29 15:01 UTC 2024-10 A078250-003 NAPROXEN 500MG TABLET / ORAL AB 2007-03-28 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 A078250-001 NAPROXEN 250MG TABLET / ORAL AB 2007-03-28 79d66fd596c7…
Observed Orange Book normalized TE history# Normalized TE history page 1 of 4 · 132 observed states.
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Naproxen
Listing expiration 2026-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength NAPROXEN 500 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 57Y76R9ATQ Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 198014 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 71335-2485 NAPROXEN TABLET [BRYANT RANCH PREPACK] 1 Current NDC, 10 package rows 20240906_1fe9a6fc-940e-4a18-b3e9-b204fd67f263.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 2 of 2 · 23 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Sample Exclude flag Status 71335-2485-0 71335248500 28 TABLET in 1 BOTTLE (71335-2485-0) 28 tablet 2024-09-03 No No Current 71335-2485-1 71335248501 30 TABLET in 1 BOTTLE (71335-2485-1) 30 tablet 2024-09-03 No No Current 71335-2485-2 71335248502 60 TABLET in 1 BOTTLE (71335-2485-2) 60 tablet 2024-09-03 No No Current 71335-2485-3 71335248503 10 TABLET in 1 BOTTLE (71335-2485-3) 10 tablet 2024-09-03 No No Current 71335-2485-4 71335248504 90 TABLET in 1 BOTTLE (71335-2485-4) 90 tablet 2024-09-03 No No Current 71335-2485-5 71335248505 20 TABLET in 1 BOTTLE (71335-2485-5) 20 tablet 2024-09-03 No No Current 71335-2485-6 71335248506 120 TABLET in 1 BOTTLE (71335-2485-6) 120 tablet 2024-09-03 No No Current 71335-2485-7 71335248507 14 TABLET in 1 BOTTLE (71335-2485-7) 14 tablet 2024-09-03 No No Current 71335-2485-8 71335248508 42 TABLET in 1 BOTTLE (71335-2485-8) 42 tablet 2024-09-03 No No Current 71335-2485-9 71335248509 40 TABLET in 1 BOTTLE (71335-2485-9) 40 tablet 2024-09-03 No No Current