Nalbuphine Hydrochloride

Product NDC
71872-7114
11-digit product format
718727114
Labeler code
71872
Product ID
71872-7114_fc5e0914-3e38-0be4-e053-6394a90aee7d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
NALBUPHINE HYDROCHLORIDE
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
Medical Purchasing Solutions, LLC
Application
ANDA070915
Marketing category
ANDA
Marketing start
2005-07-19
Substance
NALBUPHINE HYDROCHLORIDE
Active strength
10 mg/mL
Pharmacologic classes
Competitive Opioid Antagonists [MoA], Opioid Agonist/Antagonist [EPC], Partial Opioid Agonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A070915-001NALBUPHINE HYDROCHLORIDENALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A070915-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08A070915-001NALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-0384e616aacf4f…
2026-08-18 06:07:402026-07A070915-001NALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-03caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A070915-001NALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070915-001NALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A070915-001NALBUPHINE HYDROCHLORIDE100MG/10ML (10MG/ML)SOLUTION / INTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSAPRS1989-02-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-0387673890dc5c…
2021-03-12 10:30 UTC2021-03A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-035aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-038869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-033f01610625f2…
2019-09-15 20:21 UTC2019-09A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03b00525d2431f…
2019-07-19 19:46 UTC2019-07A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-036a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-031c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-039b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-033f0d92c62455…
2023-05-13 08:27 UTC2023-05A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03053a50430f4f…
2023-01-26 05:58 UTC2023-01A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-033bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-033a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070915-001NALBUPHINE HYDROCHLORIDE10MG/MLINJECTABLE / INJECTIONAPRS1989-02-03f41ea6bd6efb…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-09-14 22:38:342026-08A070915-001AP184e616aacf4f…
2026-08-18 06:07:402026-07A070915-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A070915-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070915-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A070915-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070915-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070915-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070915-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070915-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070915-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070915-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070915-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070915-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070915-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070915-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070915-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070915-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070915-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070915-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070915-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070915-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070915-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070915-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A070915-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070915-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070915-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070915-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A070915-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A070915-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070915-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070915-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070915-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070915-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070915-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070915-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070915-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A070915-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A070915-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070915-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070915-001AP1f41ea6bd6efb…

Additional Listing Data#

Finished product
Yes
Brand name base
Nalbuphine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NALBUPHINE HYDROCHLORIDE10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ZU4275277RInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
904415Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6bde2184-5643-3ec6-e053-2991aa0a115fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e665fab2-f6df-99b6-a22d-5d9276f14b80Product name320250331

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
71872-7114-1Nalbuphine Hydrochloride10 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION103
71872-7114-1Nalbuphine Hydrochloride1 in 1 BAGINJECTION, SOLUTION13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
71872-7114NALBUPHINE HYDROCHLORIDE INJECTION, SOLUTION [MEDICAL PURCHASING SOLUTIONS, LLC]3Current NDC, Legacy NDC, 2 package rows20230524_6bde2184-5643-3ec6-e053-2991aa0a115f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Nalbuphine HydrochlorideNALBUPHINE HYDROCHLORIDEHospira, Inc.6025e8d4-5083-4c3a-58a0-050e7b0b61502025-12-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070915
application number: ANDA070915
Nalbuphine HydrochlorideNALBUPHINE HYDROCHLORIDEProPharma Distribution38569b5f-fb37-135e-e063-6294a90a54df2025-12-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070915
application number: ANDA070915
NALBUPHINE HCINALBUPHINE HCIHF Acquisition Co LLC, DBA HealthFirst96139914-0708-7b58-e053-2995a90a73082025-01-08Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070915
application number: ANDA070915
Nalbuphine HydrochlorideNALBUPHINE HYDROCHLORIDEMedical Purchasing Solutions, LLC6bde2184-5643-3ec6-e053-2991aa0a115f2023-05-23Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070915
application number: ANDA070915
ndc (product): 71872-7114

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
904415nalbuphine HCl 10 MG/ML Injectable SolutionPSN6bde2184-5643-3ec6-e053-2991aa0a115f3
904415nalbuphine hydrochloride 10 MG/ML Injectable SolutionSCD6bde2184-5643-3ec6-e053-2991aa0a115f3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
71872-7114-1718727114011 VIAL, MULTI-DOSE in 1 BAG (71872-7114-1) / 10 mL in 1 VIAL, MULTI-DOSE2018-05-030000-00-00NoNoCurrent