SPIRONOLACTONE

Product NDC: 72162-1624
11-digit product format: 721621624
Labeler code: 72162
Product ID: 72162-1624_a2903367-d7ba-42ba-b6c1-69c699e1016b
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: SPIRONOLACTONE
Dosage form: TABLET
Route: ORAL
Labeler: Bryant Ranch Prepack
Application: ANDA089424
Marketing category: ANDA
Marketing start: 1986-07-23
Substance: SPIRONOLACTONE
Active strength: 25 mg/1
Pharmacologic classes: Aldosterone Antagonist [EPC], Aldosterone Antagonists [MoA]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	Approval date
A089424-001	SPIRONOLACTONE	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23
A089424-002	SPIRONOLACTONE	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11
A089424-003	SPIRONOLACTONE	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-product	TE code
A089424-001	AB
A089424-002	AB
A089424-003	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 129 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-002	SPIRONOLACTONE	50MG	TABLET / ORAL	AB	1999-08-11	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-003	SPIRONOLACTONE	100MG	TABLET / ORAL	AB	1999-08-11	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A089424-001	SPIRONOLACTONE	25MG	TABLET / ORAL	AB	1986-07-23	`301d65b070ca…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 129 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	A089424-001	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A089424-002	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A089424-003	AB	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A089424-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A089424-002	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A089424-003	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A089424-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A089424-002	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A089424-003	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-002	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A089424-003	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A089424-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A089424-002	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A089424-003	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-002	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A089424-003	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-002	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A089424-003	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-002	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A089424-003	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-002	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A089424-003	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-002	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A089424-003	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-002	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A089424-003	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A089424-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A089424-002	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A089424-003	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-002	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A089424-003	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A089424-001	AB	1	`301d65b070ca…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: SPIRONOLACTONE
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
SPIRONOLACTONE	25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
27O7W4T232	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
313096	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3791d79c-d960-4790-b689-ea32ddf7226a	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
d335cba1-5b36-51c8-120a-594ec9d05330	Product name	5	20251114
25f5e2cf-3572-477b-994c-aa692751e5a8	Product name	2	20250616
f151007d-265d-9fbe-857d-1d44f1cb76ba	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
72162-1624-0	SPIRONOLACTONE	1000 in 1 BOTTLE	TABLET	1000	109
72162-1624-1	SPIRONOLACTONE	100 in 1 BOTTLE	TABLET	100	109
72162-1624-3	SPIRONOLACTONE	30 in 1 BOTTLE	TABLET	30	109
72162-1624-5	SPIRONOLACTONE	500 in 1 BOTTLE	TABLET	500	109
72162-1624-6	SPIRONOLACTONE	60 in 1 BOTTLE	TABLET	60	109
72162-1624-9	SPIRONOLACTONE	90 in 1 BOTTLE	TABLET	90	109

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
72162-1624-0	EA - Each	72162-1624	34b5f845-d3a5-4201-896c-c73588c47ac7	1	2025-05-14
72162-1624-1	EA - Each	72162-1624	78c7cae0-2b4e-460b-9ee2-b656d9ff70e6	1	2023-07-06
72162-1624-3	EA - Each	72162-1624	4b6fd20b-e72c-427e-a885-6f56a62abd06	1	2024-01-04
72162-1624-5	EA - Each	72162-1624	7bcf5f56-f2e1-4fb5-b222-91784fd75fcf	1	2024-10-04
72162-1624-6	EA - Each	72162-1624	b437eb85-1aed-4bfd-a90f-51a1de6a35a8	1	2024-01-04
72162-1624-9	EA - Each	72162-1624	e3032663-7f96-4db7-af35-45c81aa766ae	1	2024-10-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
72162-1624	SPIRONOLACTONE TABLET [BRYANT RANCH PREPACK]	108	Current NDC, 6 package rows	20250313_3791d79c-d960-4790-b689-ea32ddf7226a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 2 of 2 · 33 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
SPIRONOLACTONE	SPIRONOLACTONE	Bryant Ranch Prepack	cae68fd6-5161-4650-bcde-6db98cbe6c8b	2026-04-03	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Bryant Ranch Prepack	b7a1f1d6-0724-4ad9-a4f9-7b1fe910f95d	2026-04-02	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Bryant Ranch Prepack	3791d79c-d960-4790-b689-ea32ddf7226a	2026-03-30	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424 ndc (product): 72162-1624
SPIRONOLACTONE	SPIRONOLACTONE	Bryant Ranch Prepack	cbc817de-5ea8-4139-9c13-02bac8ff93c3	2026-03-27	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Bryant Ranch Prepack	d4cf1136-df3a-4fc2-9a21-9032949eca41	2026-01-22	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Aphena Pharma Solutions - Tennessee, LLC	45232668-6952-80a0-e063-6294a90a6e4b	2025-12-17	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Aphena Pharma Solutions - Tennessee, LLC	fb961096-edbb-45ad-96b7-61c2f9b98cf9	2023-10-31	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Proficient Rx LP	416ce231-fc8d-4ba0-a1ce-d5e054cf025e	2023-08-01	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	A-S Medication Solutions	be568fbd-3c3d-417c-ae96-75a78ca4b7cd	2023-06-02	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	A-S Medication Solutions	4514fa40-613e-46f5-bee4-3edc7cc9863f	2023-04-16	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	A-S Medication Solutions	200b2a6a-f263-463e-a2e1-f4f74058a924	2023-04-07	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Asclemed USA, Inc.	731894f2-bb1b-4ff6-b8c4-b8722e173199	2023-04-07	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424
SPIRONOLACTONE	SPIRONOLACTONE	Proficient Rx LP	18f11eed-9ef6-43f6-8db0-720c27563871	2023-04-01	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 089424 application number: ANDA089424

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
27O7W4T232	SPIRONOLACTONE	52-01-7	SPIRONOLACTONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
313096	spironolactone 25 MG Oral Tablet	PSN	3791d79c-d960-4790-b689-ea32ddf7226a	109
313096	spironolactone 25 MG Oral Tablet	SCD	3791d79c-d960-4790-b689-ea32ddf7226a	109
313096	spironolactone 25 MG Oral Tablet	PSN	45232668-6952-80a0-e063-6294a90a6e4b	2
313096	spironolactone 25 MG Oral Tablet	SCD	45232668-6952-80a0-e063-6294a90a6e4b	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
72162-1624-0	72162162400	1000 TABLET in 1 BOTTLE (72162-1624-0)	1000 tablet	2023-11-20	No	No	Current
72162-1624-1	72162162401	100 TABLET in 1 BOTTLE (72162-1624-1)	100 tablet	2024-04-08	No	No	Current
72162-1624-3	72162162403	30 TABLET in 1 BOTTLE (72162-1624-3)	30 tablet	2025-09-15	No	No	Current
72162-1624-5	72162162405	500 TABLET in 1 BOTTLE (72162-1624-5)	500 tablet	2025-01-13	No	No	Current
72162-1624-6	72162162406	60 TABLET in 1 BOTTLE (72162-1624-6)	60 tablet	2026-03-30	No	No	Current
72162-1624-9	72162162409	90 TABLET in 1 BOTTLE (72162-1624-9)	90 tablet	2026-03-30	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
SPIRONOLACTONE	Bryant Ranch Prepack	2026-03-30	HUMAN PRESCRIPTION DRUG LABEL	109
SPIRONOLACTONE	Aphena Pharma Solutions - Tennessee, LLC	2025-12-17	HUMAN PRESCRIPTION DRUG LABEL	2