IMIQUIMOD

Product NDC
72189-084
11-digit product format
721890084
Labeler code
72189
Product ID
72189-084_2be84443-5bdd-96bd-e063-6294a90a9264
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
IMIQUIMOD
Dosage form
CREAM
Route
TOPICAL
Labeler
DIRECT RX
Application
ANDA078837
Marketing category
ANDA
Marketing start
2020-03-23
Substance
IMIQUIMOD
Active strength
12.5 mg/.25g
Pharmacologic classes
Increased Cytokine Activity [PE], Increased Cytokine Production [PE], Interferon Inducers [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopeProduct NDCPackage NDCCodeStatusReporting periodArchiveSnapshotSource SHA-256
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct72189-084UExcluded because listing certification expiredexcluded / ndc_excluded.zip0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage72189-08472189-084-24UExcluded because listing certification expiredexcluded / ndc_excluded.zip0efc9e666f02…f202fb6c5f17…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A078837-001IMIQUIMODIMIQUIMOD5%CREAM / TOPICALAB2010-09-07

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A078837-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-0787673890dc5c…
2021-03-12 10:30 UTC2021-03A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07c0c555d07b60…
2019-12-14 00:12 UTC2019-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-073f01610625f2…
2019-09-15 20:21 UTC2019-09A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07b00525d2431f…
2019-07-19 19:46 UTC2019-07A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-073f0d92c62455…
2023-05-13 08:27 UTC2023-05A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07053a50430f4f…
2023-01-26 05:58 UTC2023-01A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A078837-001IMIQUIMOD5%CREAM / TOPICALAB2010-09-07cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A078837-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078837-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A078837-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078837-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078837-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078837-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078837-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078837-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078837-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A078837-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078837-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078837-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078837-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A078837-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A078837-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A078837-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A078837-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A078837-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A078837-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A078837-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A078837-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A078837-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A078837-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A078837-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A078837-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A078837-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A078837-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A078837-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A078837-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A078837-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A078837-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A078837-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A078837-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A078837-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A078837-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A078837-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A078837-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A078837-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A078837-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A078837-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
IMIQUIMOD
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IMIQUIMOD12.5 mg/.25g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
P1QW714R7MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
310982Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a18a3f7e-7254-56c0-e053-2a95a90a7036Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
5624e12d-8450-453b-aa8d-acacc0adf764Product name120210621
b519e8a5-29e1-d8cd-ace0-3915cc880d8fProduct name220150122

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72189-084-24IMIQUIMOD0.25 g in 1 PACKETCREAM0.252

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72189-084-24EA - Each72189-084363e7ccd-c85b-4637-9420-6fb0375d83cc12020-06-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72189-084IMIQUIMOD CREAM [DIRECT RX]2Current NDC, Legacy NDC, 1 package rows20250119_a18a3f7e-7254-56c0-e053-2a95a90a7036.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 5 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ImiquimodIMIQUIMODBryant Ranch Prepack9291e5cd-b83d-4b43-88f5-30cac6cef5ff2025-11-05Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078837
application number: ANDA078837
ImiquimodIMIQUIMODBryant Ranch Prepackf8db59e2-8052-413b-9f9f-07cd9eea07ec2025-09-25Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078837
application number: ANDA078837
ImiquimodIMIQUIMODBryant Ranch Prepack47d3045f-a145-4095-bb8a-c67ba1ff3bda2025-07-29Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078837
application number: ANDA078837
ImiquimodIMIQUIMODPadagis Israel Pharmaceuticals Ltd1505cf54-37da-4b2b-9812-6ffd6a01a7c72025-01-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078837
application number: ANDA078837
IMIQUIMODIMIQUIMODDIRECT RXa18a3f7e-7254-56c0-e053-2a95a90a70362025-01-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078837
application number: ANDA078837
ndc (product): 72189-084

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
310982imiquimod 5 % Topical CreamPSNa18a3f7e-7254-56c0-e053-2a95a90a70362
310982imiquimod 50 MG/ML Topical CreamSCDa18a3f7e-7254-56c0-e053-2a95a90a70362
310982imiquimod 5 % Topical CreamSYa18a3f7e-7254-56c0-e053-2a95a90a70362

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
72189-084-2472189008424.25 g in 1 PACKET (72189-084-24) 2020-03-230000-00-00NoNoCurrent