basic care daytime cold and flu nighttime cold and flu

Product NDC: 72288-580
11-digit product format: 722880580
Labeler code: 72288
Product ID: 72288-580_3fea38da-3f5f-42b3-b1ef-372ac34ba133
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen, dextromethorphan HBr, doxylamine succinate, phenylephrine HCl
Dosage form: KIT
Labeler: Amazon.com Services LLC
Application: M012
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2021-08-26
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: basic care daytime cold and flu nighttime cold and flu
Listing expiration: 2027-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1086997	Internal RxNorm lookup
1094549	Internal RxNorm lookup
2634564	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
ceb342da-ff6d-4c19-9f78-0033d028075e	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
59361619-24d9-b610-eca6-5a7f25ed5e03	Product name	5	20240909
f4368033-af8c-41bf-a84b-ff77392b8522	Product name	1	20161229

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
72288-056-00	basic care daytime cold and flu nighttime cold and flu	8 in 1 CARTON	CAPSULE, LIQUID FILLED		6.25 mg	3
72288-056-00	basic care daytime cold and flu nighttime cold and flu	2 in 1 BLISTER PACK	CAPSULE, LIQUID FILLED	16	6.25 mg	3
72288-580-72	basic care daytime cold and flu nighttime cold and flu	1 in 1 CARTON	KIT	1		3
72288-994-00	basic care daytime cold and flu nighttime cold and flu	16 in 1 CARTON	CAPSULE, LIQUID FILLED		5 mg	3
72288-994-00	basic care daytime cold and flu nighttime cold and flu	2 in 1 BLISTER PACK	CAPSULE, LIQUID FILLED	32	10 mg	3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
72288-580	BASIC CARE DAYTIME COLD AND FLU NIGHTTIME COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL) KIT [AMAZON.COM SERVICES LLC]	3	Current NDC, Legacy NDC, 5 package rows	20241116_ceb342da-ff6d-4c19-9f78-0033d028075e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 67 of 178 · 3,550 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
MUCUS RELIEF	GUAIFENESIN 400 MG	Pioneer Life Sciences, LLC	1194c338-e115-4105-93d8-9ab833c43193	2025-12-26	Warnings	Exact identifier application number: M012
MUCUS RELIEF	GUAIFENESIN 400 MG	Pioneer Life Sciences, LLC	9c9e558d-d991-4a2e-aa13-37c0b08071e6	2025-12-26	Warnings	Exact identifier application number: M012
MUCUS RELIEF	GUAIFENESIN 400 MG	Pioneer Life Sciences, LLC	1695e7ea-2f83-4d3a-980e-c91be6c1f2a5	2025-12-25	Warnings	Exact identifier application number: M012
GUAIFENESIN	GUAIFENESIN	Pharbest Pharmaceuticals, Inc.	0bf70fb4-d3c8-476d-b864-4eadc697a7d8	2025-12-24	Warnings	Exact identifier application number: M012
PHARBINEX-DM	GUAIFENESIN 400MG AND DEXTROMETHORPHAN HBR 20MG	Pharbest Pharmaceuticals, Inc.	8d71db43-da87-45ee-aa4a-7e870bc5016d	2025-12-24	Warnings	Exact identifier application number: M012
Daytime Nighttime Cold Flu Relief	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL	Safeway, Inc.	764bcc58-bc5f-4ee6-82b7-cb0ed5baf3be	2025-12-23	Warnings	Exact identifier application number: M012
Tussin	GUAIFENESIN	Discount Drug Mart	14de3d6d-4eb0-42cf-8941-cb42b3dd5c71	2025-12-23	Warnings	Exact identifier application number: M012
Allergy Relief	DIPHENHYDRAMINE HCL 25 MG	Pioneer Life Sciences, LLC	c8dcba06-a461-4af5-a120-666a63f06ac4	2025-12-23	Warnings	Exact identifier application number: M012
SAFETUSSIN MAX STRENGTH MS Cough, Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND GUAIFENESIN	KRAMER LABORATORIES	920bde5f-4079-45de-aa59-24b00e50cb56	2025-12-23	Warnings	Exact identifier application number: M012
Daytime Cold and Flu	ACETAMINOPHEN AND DEXTROMETHORPHAN HYDROBROMIDE	Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd	46996bbf-948c-0aba-e063-6394a90a09e3	2025-12-23	Warnings	Exact identifier application number: M012
Nighttime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND DOXYLAMINE SUCCINATE	Lil' Drug Store Products, Inc.	1d2e2a5a-099b-41b3-82bd-5bf704377f78	2025-12-23	Warnings	Exact identifier application number: M012
Daytime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND PHENYLEPHRINE HYDROCHLORIDE	Lil' Drug Store Products, Inc.	5b493ed7-9044-4841-9935-236d0bdc71a9	2025-12-23	Warnings	Exact identifier application number: M012
Daytime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND PHENYLEPHRINE HYDROCHLORIDE	Lil' Drug Store Products, Inc.	77a7ff9a-a414-4053-8d8d-369907d4380d	2025-12-23	Warnings	Exact identifier application number: M012
Nighttime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND DOXYLAMINE SUCCINATE	Lil' Drug Store Products, Inc.	8f320235-f243-4211-b99c-18526e686548	2025-12-23	Warnings	Exact identifier application number: M012
Circle K Daytime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND PHENYLEPHRINE HYDROCHLORIDE	Lil' Drug Store Products, Inc.	b6a46498-d9a8-4da2-9283-57d135f305a5	2025-12-23	Warnings	Exact identifier application number: M012
Circle K Nighttime Cold and Flu	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, AND DOXYLAMINE SUCCINATE	Lil' Drug Store Products, Inc.	7c5faec2-28c6-4c15-a268-d8b578140b74	2025-12-23	Warnings	Exact identifier application number: M012
Sugar Free Honey Lemon Cough Drops	MENTHOL	Walmart	67650b94-adbb-87fb-e053-2a91aa0a87e6	2025-12-23	Warnings	Exact identifier application number: M012
Equate Benz-Dex Cough and Throat Lozenges	BENZOCAINE	Walmart	c0a6cb7f-a247-e610-e053-2a95a90a4199	2025-12-23	Warnings	Exact identifier application number: M012
Equate Honey Lemon Cough Drops	MENTHOL	WalMart	0028be18-5162-ff51-e063-6294a90ae517	2025-12-23	Warnings	Exact identifier application number: M012
Equate SF Menthol Cough Drops	MENTHOL	WalMart	003a229c-b014-e9f3-e063-6294a90aa5ed	2025-12-23	Warnings	Exact identifier application number: M012

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2634564	{1 (acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Capsule) / 1 (acetaminophen 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule) } Pack	GPCK	ceb342da-ff6d-4c19-9f78-0033d028075e	3
2634564	1 daytime (acetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG Oral Capsule) / 1 nighttime (acetaminophen 325 MG / dextromethorphan HBr 15 MG / doxylamine succinate 6.25 MG Oral Capsule) Pack	PSN	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1086997	acetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG Oral Capsule	PSN	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1094549	acetaminophen 325 MG / dextromethorphan HBr 15 MG / doxylamine succinate 6.25 MG Oral Capsule	PSN	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1086997	acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Capsule	SCD	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1094549	acetaminophen 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule	SCD	ceb342da-ff6d-4c19-9f78-0033d028075e	3
2634564	1 daytime (acetaminophen 325 MG / dextromethorphan HBr 10 MG / phenylephrine HCl 5 MG Oral Capsule) / 1 nighttime (acetaminophen 325 MG / dextromethorphan HBr 15 MG / doxylamine succinate 6.25 MG Oral Capsule) Pack	SY	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1086997	APAP 325 MG / dextromethorphan hydrobromide 10 MG / phenylephrine hydrochloride 5 MG Oral Capsule	SY	ceb342da-ff6d-4c19-9f78-0033d028075e	3
1094549	APAP 325 MG / dextromethorphan hydrobromide 15 MG / doxylamine succinate 6.25 MG Oral Capsule	SY	ceb342da-ff6d-4c19-9f78-0033d028075e	3

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
72288-056-00	72288005600	8 in 1 CARTON						Historical
72288-580-72	72288058072	1 KIT in 1 CARTON (72288-580-72) * 8 BLISTER PACK in 1 CARTON (72288-056-00) / 2 CAPSULE, LIQUID FILLED in 1 BLISTER PACK * 16 BLISTER PACK in 1 CARTON (72288-994-00) / 2 CAPSULE, LIQUID FILLED in 1 BLISTER PACK	1 kit	2021-08-26	0000-00-00	No	No	Current
72288-994-00	72288099400	16 in 1 CARTON						Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Amazon Daytime Cold & Flu Nighttime Cold & Flu Drug Facts	Amazon.com Services LLC	2024-11-14	HUMAN OTC DRUG LABEL	3