Nexletol

Product NDC
72426-118
Requested package NDC
72426-118-99
11-digit product format
724260118
Labeler code
72426
Product ID
72426-118_75423e10-bf22-4ef2-81de-fa6451541020
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Bempedoic Acid
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Esperion Therapeutics, Inc.
Application
NDA211616
Marketing category
NDA
Marketing start
2020-03-06
Substance
BEMPEDOIC ACID
Active strength
180 mg/1
Pharmacologic classes
Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC], Adenosine Triphosphate-Citrate Lyase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N211616-001NEXLETOLBEMPEDOIC ACID180MGTABLET / ORALRLD, RS2020-02-21

Orange Book patents#

Current patent rows page 1 of 1 · 7 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N211616-00173357992030-12-03Drug substance2020-03-06
N211616-001117448162036-03-14U-38832024-04-19
N211616-001116135112040-06-19Drug substance2023-04-20
N211616-001117607142040-06-19Drug product2023-10-03
N211616-001119265842040-06-19U-38732024-04-09
N211616-001123980872040-06-19Drug substance, Drug product2025-09-09
N211616-001124042272040-06-19U-4258Drug substance2025-09-09

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N211616-001I-9432027-03-22
N211616-001I-9442027-03-22

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-214b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-2187673890dc5c…
2021-03-12 10:30 UTC2021-03N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-215aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-218869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-211c564ffb4f44…
2023-12-20 04:57 UTC2023-12N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-213f0d92c62455…
2023-05-13 08:27 UTC2023-05N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21053a50430f4f…
2023-01-26 05:58 UTC2023-01N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-213bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-213a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N211616-001NEXLETOL180MGTABLET / ORALRLD, RS2020-02-21a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 6 · 212 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211616-00173357992030-12-03Drug substance2020-03-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001117448162036-03-14U-38832024-04-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001116135112040-06-19Drug substance2023-04-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001117607142040-06-19Drug product2023-10-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001119265842040-06-19U-38732024-04-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001123980872040-06-19Drug substance, Drug product2025-09-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001124042272040-06-19U-4258Drug substance2025-09-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-00173357992030-12-03Drug substance2020-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001117448162036-03-14U-38832024-04-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001116135112040-06-19Drug substance2023-04-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001117607142040-06-19Drug product2023-10-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001119265842040-06-19U-38732024-04-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001123980872040-06-19Drug substance, Drug product2025-09-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001124042272040-06-19U-4258Drug substance2025-09-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N211616-00173357992030-12-03Drug substance2020-03-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001117448162036-03-14U-38832024-04-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001116135112040-06-19Drug substance2023-04-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001117607142040-06-19Drug product2023-10-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001119265842040-06-19U-38732024-04-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-00173357992030-12-03Drug substance2020-03-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001117448162036-03-14U-38832024-04-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001116135112040-06-19Drug substance2023-04-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001117607142040-06-19Drug product2023-10-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001119265842040-06-19U-38732024-04-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-00173357992030-12-03Drug substance2020-03-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001117448162036-03-14U-38832024-04-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001116135112040-06-19Drug substance2023-04-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001117607142040-06-19Drug product2023-10-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001119265842040-06-19U-38732024-04-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-00173357992030-12-03Drug substance2020-03-0603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001117448162036-03-14U-38832024-04-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001116135112040-06-19Drug substance2023-04-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001117607142040-06-19Drug product2023-10-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001119265842040-06-19U-38732024-04-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-00173357992030-12-03Drug substance2020-03-062680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001117448162036-03-14U-38832024-04-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001116135112040-06-19Drug substance2023-04-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001117607142040-06-19Drug product2023-10-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001119265842040-06-19U-38732024-04-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211616-00173357992030-12-03Drug substance2020-03-065bbf6a4d5a75…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 63 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N211616-001I-9432027-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211616-001I-9442027-03-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001NCE2025-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001I-9432027-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211616-001I-9442027-03-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N211616-001NCE2025-02-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001I-9432027-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211616-001I-9442027-03-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001NCE2025-02-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001I-9432027-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211616-001I-9442027-03-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001NCE2025-02-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001I-9432027-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211616-001I-9442027-03-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001NCE2025-02-2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001I-9432027-03-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211616-001I-9442027-03-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001NCE2025-02-212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001I-9432027-03-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211616-001I-9442027-03-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211616-001NCE2025-02-215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211616-001I-9432027-03-225bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211616-001I-9442027-03-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211616-001NCE2025-02-21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211616-001I-9432027-03-22d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211616-001I-9442027-03-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211616-001NCE2025-02-21d06236e962d9…
2024-10-29 15:01 UTC2024-10N211616-001I-9432027-03-22d06236e962d9…
2024-10-29 15:01 UTC2024-10N211616-001I-9442027-03-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211616-001NCE2025-02-2179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211616-001I-9432027-03-2279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211616-001I-9442027-03-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211616-001NCE2025-02-21301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211616-001I-9432027-03-22301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211616-001I-9442027-03-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211616-001NCE2025-02-211e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211616-001I-9432027-03-221e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211616-001I-9442027-03-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211616-001NCE2025-02-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211616-001NCE2025-02-215c6f7cd8ea54…

Additional Listing Data#

Finished product
Yes
Brand name base
Nexletol
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BEMPEDOIC ACID180 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1EJ6Z6Q368Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2282408Internal RxNorm lookup
2282414Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
88d06d89-a3da-40b4-b273-8f4f7d56c4c9Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b249faa8-b784-47ef-8ad4-031ef248fa73Product name120200626
6950fe3e-c2b8-4615-b800-ed1730fa68b6Product name120200623

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72426-118-03Nexletol30 in 1 BOTTLE, PLASTICTABLET, FILM COATED3019
72426-118-99Nexletol7 in 1 BLISTER PACKTABLET, FILM COATED719

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72426-118-03EA - Each72426-118991aa193-a0bd-4214-9d78-dc9c123cff8112020-04-20

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72426-118NEXLETOL (BEMPEDOIC ACID) TABLET, FILM COATED [ESPERION THERAPEUTICS, INC.]14Current NDC, Legacy NDC, 2 package rows20241207_88d06d89-a3da-40b4-b273-8f4f7d56c4c9.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
NexletolBEMPEDOIC ACIDEsperion Therapeutics, Inc.88d06d89-a3da-40b4-b273-8f4f7d56c4c92026-06-25Warnings, Adverse reactionsExact identifier
application applno (NDA): 211616
application number: NDA211616
ndc (package): 72426-118-99
ndc (product): 72426-118
ndc11 (package): 72426011899

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2282408bempedoic acid 180 MG Oral TabletPSN88d06d89-a3da-40b4-b273-8f4f7d56c4c919
2282414NEXLETOL 180 MG Oral TabletPSN88d06d89-a3da-40b4-b273-8f4f7d56c4c919
2282414bempedoic acid 180 MG Oral Tablet [Nexletol]SBD88d06d89-a3da-40b4-b273-8f4f7d56c4c919
2282408bempedoic acid 180 MG Oral TabletSCD88d06d89-a3da-40b4-b273-8f4f7d56c4c919
2282414Nexletol 180 MG Oral TabletSY88d06d89-a3da-40b4-b273-8f4f7d56c4c919

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
72426-118-99724260118997 TABLET, FILM COATED in 1 BLISTER PACK (72426-118-99) 2020-03-060000-00-00NoNoCurrent