Intrarosa

Product NDC
72495-501
11-digit product format
724950501
Labeler code
72495
Product ID
72495-501_2b9876fb-e9e0-4dbc-e063-6294a90a8696
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Prasterone
Dosage form
INSERT
Route
VAGINAL
Labeler
Millicent US, Inc.
Application
NDA208470
Marketing category
NDA
Marketing start
2020-11-01
Substance
PRASTERONE
Active strength
6.5 mg/1
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopeProduct NDCPackage NDCCodeStatusReporting periodArchiveSnapshotSource SHA-256
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct72495-501UExcluded because listing certification expiredexcluded / ndc_excluded.zip0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage72495-50172495-501-14UExcluded because listing certification expiredexcluded / ndc_excluded.zip0efc9e666f02…f202fb6c5f17…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208470-001INTRAROSAPRASTERONE6.5MGINSERT / VAGINALRLD, RS2016-11-16

Orange Book patents#

Current patent rows page 1 of 1 · 3 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N208470-00186291292028-08-07Drug product2016-12-08
N208470-00189570542030-01-08U-19222016-12-08
N208470-00182688062031-03-19Drug product2016-12-08

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-164b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-1674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-1687673890dc5c…
2021-03-12 10:30 UTC2021-03N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-165aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-168869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-163f01610625f2…
2019-09-15 20:21 UTC2019-09N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16b00525d2431f…
2019-07-19 19:46 UTC2019-07N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-166a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-161c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-169b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-163f0d92c62455…
2023-05-13 08:27 UTC2023-05N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16053a50430f4f…
2023-01-26 05:58 UTC2023-01N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-163bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-163a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208470-001INTRAROSA6.5MGINSERT / VAGINALRLD, RS2016-11-16e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N208470-00186291292028-08-07Drug product2016-12-08caaa826d4ba7…
2026-08-18 06:07:402026-07N208470-00189570542030-01-08U-19222016-12-08caaa826d4ba7…
2026-08-18 06:07:402026-07N208470-00182688062031-03-19Drug product2016-12-08caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208470-00186291292028-08-07Drug product2016-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208470-00189570542030-01-08U-19222016-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208470-00182688062031-03-19Drug product2016-12-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208470-00186291292028-08-07Drug product2016-12-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208470-00189570542030-01-08U-19222016-12-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208470-00182688062031-03-19Drug product2016-12-0831067a03dcf5…
2025-08-23 18:47 UTC2025-08N208470-00186291292028-08-07Drug product2016-12-086a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208470-00189570542030-01-08U-19222016-12-086a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208470-00182688062031-03-19Drug product2016-12-086a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208470-00186291292028-08-07Drug product2016-12-08fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208470-00189570542030-01-08U-19222016-12-08fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208470-00182688062031-03-19Drug product2016-12-08fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208470-00186291292028-08-07Drug product2016-12-08b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208470-00189570542030-01-08U-19222016-12-08b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208470-00182688062031-03-19Drug product2016-12-08b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208470-00186291292028-08-07Drug product2016-12-0803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208470-00189570542030-01-08U-19222016-12-0803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208470-00182688062031-03-19Drug product2016-12-0803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208470-00186291292028-08-07Drug product2016-12-082680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208470-00189570542030-01-08U-19222016-12-082680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208470-00182688062031-03-19Drug product2016-12-082680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208470-00186291292028-08-07Drug product2016-12-085bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208470-00189570542030-01-08U-19222016-12-085bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208470-00182688062031-03-19Drug product2016-12-085bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208470-00186291292028-08-07Drug product2016-12-08d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208470-00189570542030-01-08U-19222016-12-08d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208470-00182688062031-03-19Drug product2016-12-08d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208470-00186291292028-08-07Drug product2016-12-08d06236e962d9…
2024-10-29 15:01 UTC2024-10N208470-00189570542030-01-08U-19222016-12-08d06236e962d9…
2024-10-29 15:01 UTC2024-10N208470-00182688062031-03-19Drug product2016-12-08d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208470-00186291292028-08-07Drug product2016-12-0879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208470-00189570542030-01-08U-19222016-12-0879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208470-00182688062031-03-19Drug product2016-12-0879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208470-00186291292028-08-07Drug product2016-12-08301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208470-00189570542030-01-08U-19222016-12-08301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208470-00182688062031-03-19Drug product2016-12-08301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208470-00186291292028-08-07Drug product2016-12-081e350fbaab3a…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N208470-001NCE2021-11-1674a2ff9319b5…
2021-12-28 21:50 UTC2021-12N208470-001NCE2021-11-16782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208470-001NCE2021-11-1687673890dc5c…
2021-03-12 10:30 UTC2021-03N208470-001NCE2021-11-165aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208470-001NCE2021-11-168869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208470-001NCE2021-11-16c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208470-001NCE2021-11-163f01610625f2…
2019-09-15 20:21 UTC2019-09N208470-001NCE2021-11-16b00525d2431f…
2019-07-19 19:46 UTC2019-07N208470-001NCE2021-11-16ea99ee380514…

Additional Listing Data#

Finished product
Yes
Brand name base
Intrarosa
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PRASTERONE6.5 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
459AG36T1BInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1927688Internal RxNorm lookup
1927693Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ada639d4-bac0-2ad0-e053-2a95a90afce7Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
86ca2ee7-106a-420e-9137-a9ec1af5dbc1Product name120170110

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72495-501-14Intrarosa14 in 1 BOXINSERT145
72495-501-14Intrarosa1 in 1 BOXINSERT15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72495-501INTRAROSA (PRASTERONE) INSERT [MILLICENT US, INC.]5Current NDC, Legacy NDC, 2 package rows20250114_ada639d4-bac0-2ad0-e053-2a95a90afce7.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IntrarosaPRASTERONEMillicent US, Inc.ada639d4-bac0-2ad0-e053-2a95a90afce72026-07-17Warnings, Adverse reactionsExact identifier
application applno (NDA): 208470
application number: NDA208470
ndc (product): 72495-501

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1927693Intrarosa 6.5 MG Vaginal InsertPSNada639d4-bac0-2ad0-e053-2a95a90afce75
1927688prasterone 6.5 MG Vaginal InsertPSNada639d4-bac0-2ad0-e053-2a95a90afce75
1927693prasterone 6.5 MG Vaginal Insert [Intrarosa]SBDada639d4-bac0-2ad0-e053-2a95a90afce75
1927688prasterone 6.5 MG Vaginal InsertSCDada639d4-bac0-2ad0-e053-2a95a90afce75
1927688dehydroepiandrosterone (prasterone) 6.5 MG Vaginal InsertSYada639d4-bac0-2ad0-e053-2a95a90afce75
1927693Intrarosa (prasterone) 6.5 MG Vaginal InsertSYada639d4-bac0-2ad0-e053-2a95a90afce75
1927693Intrarosa 6.5 MG Vaginal InsertSYada639d4-bac0-2ad0-e053-2a95a90afce75

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
72495-501-14724950501141 BOX in 1 BOX (72495-501-14) / 14 BLISTER PACK in 1 BOX / 1 INSERT in 1 BLISTER PACK1 box2020-11-010000-00-00NoNoCurrent