PEDMARK

Product NDC
73077-010
11-digit product format
730770010
Labeler code
73077
Product ID
73077-010_889accaa-7f62-4da4-84ea-80ecfb144209
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
SODIUM THIOSULFATE
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Fennec Pharmaceuticals Inc.
Application
NDA212937
Marketing category
NDA
Marketing start
2022-10-03
Substance
SODIUM THIOSULFATE
Active strength
12.5 g/100mL
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N212937-001PEDMARKSODIUM THIOSULFATE12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20

Orange Book patents#

Current patent rows page 1 of 1 · 7 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N212937-001105961902038-01-05U-3443Delist requested2022-10-06
N212937-001112917282039-07-01Drug product2022-10-06
N212937-001115109842039-07-01Drug product2022-12-14
N212937-001116177932039-07-01Drug product2023-04-17
N212937-001119640182039-07-01U-38982024-05-08
N212937-001119925302039-07-01U-39482024-06-20
N212937-001119986042039-07-01U-39522024-06-24

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 1 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N212937-001ODE-3842029-09-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-208072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-209b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-203f0d92c62455…
2023-05-13 08:27 UTC2023-05N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20053a50430f4f…
2023-01-26 05:58 UTC2023-01N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-203bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-203a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20f41ea6bd6efb…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N212937-001PEDMARK12.5GM/100ML (125MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-09-20a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 4 · 144 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N212937-001105961902038-01-05U-3443Delist requested2022-10-06caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001112917282039-07-01Drug product2022-10-06caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001115109842039-07-01Drug product2022-12-14caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001116177932039-07-01Drug product2023-04-17caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001119640182039-07-01U-38982024-05-08caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001119925302039-07-01U-39482024-06-20caaa826d4ba7…
2026-08-18 06:07:402026-07N212937-001119986042039-07-01U-39522024-06-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N212937-001105961902038-01-05U-3443Delist requested2022-10-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001112917282039-07-01Drug product2022-10-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001115109842039-07-01Drug product2022-12-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001116177932039-07-01Drug product2023-04-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001119640182039-07-01U-38982024-05-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001119925302039-07-01U-39482024-06-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212937-001119986042039-07-01U-39522024-06-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001105961902038-01-05U-3443Delist requested2022-10-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001112917282039-07-01Drug product2022-10-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001115109842039-07-01Drug product2022-12-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001116177932039-07-01Drug product2023-04-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001119640182039-07-01U-38982024-05-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001119925302039-07-01U-39482024-06-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001119986042039-07-01U-39522024-06-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N212937-001105961902038-01-05U-3443Delist requested2022-10-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001112917282039-07-01Drug product2022-10-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001115109842039-07-01Drug product2022-12-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001116177932039-07-01Drug product2023-04-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001119640182039-07-01U-38982024-05-086a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001119925302039-07-01U-39482024-06-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001119986042039-07-01U-39522024-06-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001105961902038-01-05U-3443Delist requested2022-10-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001112917282039-07-01Drug product2022-10-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001115109842039-07-01Drug product2022-12-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001116177932039-07-01Drug product2023-04-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001119640182039-07-01U-38982024-05-08fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001119925302039-07-01U-39482024-06-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001119986042039-07-01U-39522024-06-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001105961902038-01-05U-3443Delist requested2022-10-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001112917282039-07-01Drug product2022-10-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001115109842039-07-01Drug product2022-12-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001116177932039-07-01Drug product2023-04-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001119640182039-07-01U-38982024-05-08b8a1b40f171c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 46 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N212937-001ODE-3842029-09-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N212937-001ODE-3842029-09-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001NP2025-09-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212937-001ODE-3842029-09-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N212937-001NP2025-09-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212937-001ODE-3842029-09-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001NP2025-09-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212937-001ODE-3842029-09-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001NP2025-09-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212937-001ODE-3842029-09-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212937-001NP2025-09-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212937-001ODE-3842029-09-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212937-001NP2025-09-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212937-001ODE-3842029-09-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212937-001NP2025-09-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212937-001ODE-3842029-09-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212937-001NP2025-09-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212937-001ODE-3842029-09-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N212937-001NP2025-09-20d06236e962d9…
2024-10-29 15:01 UTC2024-10N212937-001ODE-3842029-09-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212937-001NP2025-09-2079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212937-001ODE-3842029-09-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N212937-001NP2025-09-20301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N212937-001ODE-3842029-09-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N212937-001NP2025-09-201e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N212937-001ODE-3842029-09-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05N212937-001NP2025-09-208072bd15b7f6…
2024-05-31 18:47 UTC2024-05N212937-001ODE-3842029-09-208072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N212937-001NP2025-09-206a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N212937-001ODE-3842029-09-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N212937-001NP2025-09-201c564ffb4f44…
2024-02-18 07:12 UTC2024-02N212937-001ODE-3842029-09-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12N212937-001NP2025-09-20ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N212937-001ODE-3842029-09-20ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N212937-001NP2025-09-20a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N212937-001ODE-3842029-09-20a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N212937-001NP2025-09-209b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N212937-001ODE-3842029-09-209b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N212937-001NP2025-09-20a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N212937-001ODE-3842029-09-20a67488948f0b…

Additional Listing Data#

Finished product
Yes
Brand name base
PEDMARK
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SODIUM THIOSULFATE12.5 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
HX1032V43MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2618749Internal RxNorm lookup
2618755Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f98c7076-2a7b-4fd7-ab90-eed5e9137baeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4073022c-5d5d-48f5-82ed-091ad146a4b2Product name120171211
9ffbd0ae-0bce-c086-b707-f0da5f8cd7c5Product name120150828

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
73077-010-01PEDMARK100 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION1007
73077-010-01PEDMARK1 in 1 BOX, UNIT-DOSEINJECTION, SOLUTION17

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
73077-010-01ML - Milliliter73077-01050961911-292b-4f04-80cd-028c797d45cb12022-11-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
73077-010PEDMARK (SODIUM THIOSULFATE) INJECTION, SOLUTION [FENNEC PHARMACEUTICALS INC.]6Current NDC, Legacy NDC, 2 package rows20241027_f98c7076-2a7b-4fd7-ab90-eed5e9137bae.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PEDMARKSODIUM THIOSULFATEFennec Pharmaceuticals Inc.f98c7076-2a7b-4fd7-ab90-eed5e9137bae2025-10-27Warnings, Adverse reactionsExact identifier
application applno (NDA): 212937
application number: NDA212937
ndc (product): 73077-010

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2618755pedmark 12.5 GM in 100 ML InjectionPSNf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618749sodium thiosulfate 12.5 GM in 100 ML InjectionPSNf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618755100 ML sodium thiosulfate 125 MG/ML Injection [Pedmark]SBDf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618749100 ML sodium thiosulfate 125 MG/ML InjectionSCDf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618755100 ML Pedmark 125 MG/ML InjectionSYf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618755Pedmark 12.5 GM per 100 ML InjectionSYf98c7076-2a7b-4fd7-ab90-eed5e9137bae7
2618749sodium thiosulfate 12.5 GM per 100 ML InjectionSYf98c7076-2a7b-4fd7-ab90-eed5e9137bae7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
73077-010-01730770010011 VIAL, SINGLE-DOSE in 1 BOX, UNIT-DOSE (73077-010-01) / 100 mL in 1 VIAL, SINGLE-DOSE2022-10-030000-00-00NoNoCurrent