Clear Anti-Itch

Product NDC: 75981-218
11-digit product format: 759810218
Labeler code: 75981
Product ID: 75981-218_4b30e9a2-0f28-15ba-e063-6394a90aaa7a
Type: HUMAN OTC DRUG
Nonproprietary name: Pramoxine HCl, Zinc acetate
Dosage form: LOTION
Route: TOPICAL
Labeler: Perrigo Direct, Inc
Application: M016
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2008-07-24
Substance: PRAMOXINE HYDROCHLORIDE; ZINC ACETATE
Active strength: 10; 1 mg/mL; mg/mL
Pharmacologic classes: Copper Absorption Inhibitor [EPC], Decreased Copper Ion Absorption [PE]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Clear Anti-Itch
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
PRAMOXINE HYDROCHLORIDE	10 mg/mL
ZINC ACETATE	1 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
88AYB867L5	Internal UNII lookup
FM5526K07A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1234546	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
cc0378f2-6d5f-47ec-b16a-64668b4c29cc	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
58f3f9b7-3b9b-a9c1-1c9f-18ac777192b8	Product name	1	20140508
a7051cba-790b-a699-81f8-dbbbdbd9b5ac	Product name	1	20140508
da108d9e-edc8-17a3-8c28-3251c6a8accc	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
75981-218-30	Clear Anti-Itch	177 mL in 1 BOTTLE, PLASTIC	LOTION	177		5

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
75981-218	CLEAR ANTI-ITCH (PRAMOXINE HCL, ZINC ACETATE) LOTION [PERRIGO DIRECT, INC.]	3	Current NDC, 1 package rows	20250510_cc0378f2-6d5f-47ec-b16a-64668b4c29cc.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 21 of 68 · 1,357 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Daily Moisturizing	DIMETHICONE	Topco Associates LLC	47e54eee-70e0-4bfa-ae77-d61a6560a9e1	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M016
Witch Hazel	WITCH HAZEL	Topco Associates LLC	471a9f8d-ba12-41d3-a510-20c1a13ff850	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M016
Skin Protectant	PETROLATUM	Wakefern Food Corp.	b799229b-f7ca-494c-afde-1fd096aef66e	2026-02-13	Warnings, Adverse reactions	Exact identifier application number: M016
Diaper Rash	ZINC OXIDE	WinCo Foods, LLC	659cc8c7-6300-41c0-a684-c5fde7f2b100	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M016
Zinc Oxide	ZINC OXIDE	Walgreen Co.	220f70e1-0802-4fe2-92d0-78dec557c993	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M016
Witch Hazel	WITCH HAZEL	Walgreen Co.	417ae199-54bb-420f-a3cf-1c096062d78c	2026-02-12	Warnings, Adverse reactions	Exact identifier application number: M016
First Aid Beauty Dry Skin Rescue Kit	COLLOIDAL OATMEAL	The Procter & Gamble Manufacturing Company	4a93d029-d721-0bb5-e063-6294a90a17c4	2026-02-11	Warnings	Exact identifier application number: M016
Natouch Eczema Wipes	ECZEMA WIPES	Natouch LLC	0a9756a4-2fa9-cd19-e063-6294a90a93ad	2026-02-10	Warnings	Exact identifier application number: M016
EARTHS CARE Eczema Cream	ECZEMA	DLC Laboratories, Inc.	17436fa0-d6c7-1052-e063-6294a90adae4	2026-02-09	Warnings	Exact identifier application number: M016
Petrolatum	WHITE PETROLATUM	Retail Business Services, LLC	bf0c9494-0138-4346-9348-e235ca4d9e58	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M016
Clear Anti-Itch	PRAMOXINE HCL, ZINC ACETATE	Retail Business Services, LLC	a80b8fee-2dd9-4640-a4f8-4cf940df8563	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M016
Advanced Healing	PETROLATUM	Retail Business Services, LLC	6e9121c8-5eb9-4d0b-86c5-b892e14bdab8	2026-02-06	Warnings	Exact identifier application number: M016
Petrolatum	WHITE PETROLATUM	Retail Business Services, LLC	bf73c618-ed2f-4468-a51f-ff61c7b1f506	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M016
Daily Moisturizing	DIMETHICONE	Retail Business Services, LLC	c8a876e2-0a34-4c3d-a0bc-549dd3048e8a	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M016
Petroleum	WHITE PETROLATUM	Salado Sales Inc.	f973e3a5-3b45-4842-99ce-dff676ae1f96	2026-02-06	Warnings, Adverse reactions	Exact identifier application number: M016
Petroleum Skin Protectant	WHITE PETROLATUM	Pharmacy Value Alliance, LLC	0ce03cd1-c48d-45cf-b11f-08bade55dcb6	2026-02-05	Warnings, Adverse reactions	Exact identifier application number: M016
Daily Moisturizing	DIMETHICONE	Publix Super Markets, Inc.	28ac9de4-2a63-4839-bed5-9bcc59ebeb2a	2026-02-05	Warnings, Adverse reactions	Exact identifier application number: M016
Witch Hazel	WITCH HAZEL	Publix Super Markets, Inc.	0098c983-c518-4a14-8635-c7bdde7bff4f	2026-02-05	Warnings, Adverse reactions	Exact identifier application number: M016
TN Dickinsons Pain and Itch Relief	PRAMOXINE HYDROCHLORIDE AND ZINC ACETATE	Dickinson Brands Inc.	537c9c27-ee81-4920-8e3f-21edb844c9cf	2026-02-05	Warnings	Exact identifier application number: M016
Aveeno Eczema Therapy Nighttime Itch Relief Balm	COLLOIDAL OATMEAL	Kenvue Brands LLC	e3350a8f-b983-7c4d-e053-2a95a90a53f5	2026-02-04	Warnings	Exact identifier application number: M016

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
88AYB867L5	PRAMOXINE HYDROCHLORIDE	637-58-1	PRAMOXINE HYDROCHLORIDE
FM5526K07A	ZINC ACETATE	5970-45-6	ZINC ACETATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1234546	pramoxine HCl 1 % / zinc acetate 0.1 % Topical Lotion	PSN	cc0378f2-6d5f-47ec-b16a-64668b4c29cc	5
1234546	pramoxine hydrochloride 10 MG/ML / zinc acetate 1 MG/ML Topical Lotion	SCD	cc0378f2-6d5f-47ec-b16a-64668b4c29cc	5
1234546	pramoxine HCl 1 % / zinc acetate 0.1 % Topical Lotion	SY	cc0378f2-6d5f-47ec-b16a-64668b4c29cc	5

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Sample	Exclude flag	Status
75981-218-30	75981021830	177 mL in 1 BOTTLE, PLASTIC (75981-218-30)	177 ml	2008-07-24	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Good Sense 218.002/218AF Clear Anti-Itch Lotion	Perrigo Direct, Inc \| Nice-Pak Products, LLC	2026-02-19	HUMAN OTC DRUG LABEL	5