ISOVUE-M

Product NDC
76381-412
11-digit product format
763810412
Labeler code
76381
Product ID
76381-412_d038c2e6-5270-c2ac-9900-523456ef927c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
IOPAMIDOL
Dosage form
INJECTION, SOLUTION
Route
INTRATHECAL
Labeler
BIPSO GmbH
Application
NDA018735
Marketing category
NDA
Marketing start
1985-12-31
Marketing end
0000-00-00
Substance
IOPAMIDOL
Active strength
612 mg/mL
Pharmacologic classes
Radiographic Contrast Agent [EPC],X-Ray Contrast Activity [MoA]
NDC exclude flag
No
Listing certified through
2019-12-31
Current FDA listing
Historical FDA.report record

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 7 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N018735-001ISOVUE-M 200IOPAMIDOL41%INJECTABLE / INJECTIONAP1RLD, RS1985-12-31
N018735-002ISOVUE-300IOPAMIDOL61%INJECTABLE / INJECTIONAPRLD, RS1985-12-31
N018735-003ISOVUE-370IOPAMIDOL76%INJECTABLE / INJECTIONAPRLD, RS1985-12-31
N018735-004ISOVUE-M 300IOPAMIDOL61%INJECTABLE / INJECTIONAPRLD, RS1985-12-31
N018735-005ISOVUE-128IOPAMIDOL26%INJECTABLE / INJECTION1986-10-21
N018735-006ISOVUE-200IOPAMIDOL41%INJECTABLE / INJECTIONAP2RLD, RS1987-07-07
N018735-007ISOVUE-250IOPAMIDOL51%INJECTABLE / INJECTIONAPRLD, RS1992-07-06

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 6 matching rows.

Application-product, TE code table
Application-productTE code
N018735-001AP1
N018735-002AP
N018735-003AP
N018735-004AP
N018735-006AP2
N018735-007AP

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 4 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N018735-002I-9752028-10-10
N018735-003I-9752028-10-10
N018735-006I-9752028-10-10
N018735-007I-9752028-10-10

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 8 · 287 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-006ISOVUE-20041%INJECTABLE / INJECTIONAP2RLD, RS1987-07-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-007ISOVUE-25051%INJECTABLE / INJECTIONAPRLD, RS1992-07-06011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-006ISOVUE-20041%INJECTABLE / INJECTIONAP2RLD, RS1987-07-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-007ISOVUE-25051%INJECTABLE / INJECTIONAPRLD, RS1992-07-0631067a03dcf5…
2025-08-23 18:47 UTC2025-08N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-006ISOVUE-20041%INJECTABLE / INJECTIONAP2RLD, RS1987-07-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-007ISOVUE-25051%INJECTABLE / INJECTIONAPRLD, RS1992-07-066a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-006ISOVUE-20041%INJECTABLE / INJECTIONAP2RLD, RS1987-07-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-007ISOVUE-25051%INJECTABLE / INJECTIONAPRLD, RS1992-07-06fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-31b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-006ISOVUE-20041%INJECTABLE / INJECTIONAP2RLD, RS1987-07-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-007ISOVUE-25051%INJECTABLE / INJECTIONAPRLD, RS1992-07-06b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-001ISOVUE-M 20041%INJECTABLE / INJECTIONAP1RLD, RS1985-12-3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-002ISOVUE-30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-003ISOVUE-37076%INJECTABLE / INJECTIONAPRLD, RS1985-12-3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-004ISOVUE-M 30061%INJECTABLE / INJECTIONAPRLD, RS1985-12-3103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-005ISOVUE-12826%INJECTABLE / INJECTION1986-10-2103ed91905a0d…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N018735-001AP11011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-003AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-004AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-006AP21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-007AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-001AP1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-003AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-004AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-006AP2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-007AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N018735-001AP116a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-003AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-004AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-006AP216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018735-007AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-001AP11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-003AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-004AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-006AP21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018735-007AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-001AP11b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-003AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-004AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-006AP21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018735-007AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-001AP1103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-003AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-004AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-006AP2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018735-007AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018735-001AP112680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018735-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018735-003AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018735-004AP12680178bc6a6…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N018735-002I-9752028-10-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-003I-9752028-10-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-006I-9752028-10-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018735-007I-9752028-10-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-002I-9752028-10-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-003I-9752028-10-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-006I-9752028-10-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018735-007I-9752028-10-1031067a03dcf5…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N018735-002I-9752028-10-10a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N018735-003I-9752028-10-10a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N018735-006I-9752028-10-10a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N018735-007I-9752028-10-10a50c72e98297…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ISOVUE 200IOPAMIDOLBRACCO DIAGNOSTICS INCae8c18c9-3e7d-4515-b980-120025a88fc12026-03-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 018735
application number: NDA018735
ISOVUE-MIOPAMIDOLBracco Diagnostics Inc11e893d2-0183-4581-b908-c8b7302c7edb2026-02-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 018735
application number: NDA018735