Calypxo Pain Relief

Product NDC: 76420-450
11-digit product format: 764200450
Labeler code: 76420
Product ID: 76420-450_07cec8ef-ecc9-ac49-e063-6294a90a6083
Type: HUMAN OTC DRUG
Nonproprietary name: Methyl Salicylate, Menthol
Dosage form: CREAM
Route: TOPICAL
Labeler: Asclemed USA, Inc
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2014-01-15
Substance: METHYL SALICYLATE; MENTHOL
Active strength: 10; 3 g/100g; g/100g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Calypxo Pain Relief
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
METHYL SALICYLATE	10 g/100g
MENTHOL	3 g/100g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
LAV5U5022Y	Internal UNII lookup
L7T10EIP3A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1486874	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
76420-450-12	Calypxo Pain Relief	113 g in 1 BOTTLE	CREAM	113		6

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
76420-450-12	GM - Gram	76420-450	e387b485-2d49-4f5c-bfa1-3c2fa94acbe0	1	2014-02-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Menthol	ACTIVE INGREDIENT	L7T10EIP3A	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Methyl Salicylate	ACTIVE INGREDIENT	LAV5U5022Y	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Menthol	ACTIVE MOIETY	L7T10EIP3A	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
SALICYLIC ACID	ACTIVE MOIETY	O414PZ4LPZ	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Aloe Vera Leaf	INACTIVE INGREDIENT	ZY81Z83H0X	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
CARBOMER INTERPOLYMER TYPE A (ALLYL SUCROSE CROSSLINKED)	INACTIVE INGREDIENT	59TL3WG5CO	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Cetyl Alcohol	INACTIVE INGREDIENT	936JST6JCN	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Diazolidinyl Urea	INACTIVE INGREDIENT	H5RIZ3MPW4	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Isopropyl Myristate	INACTIVE INGREDIENT	0RE8K4LNJS	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
MethylParaben	INACTIVE INGREDIENT	A2I8C7HI9T	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
POLYETHYLENE GLYCOL 400	INACTIVE INGREDIENT	B697894SGQ	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Propylene Glycol	INACTIVE INGREDIENT	6DC9Q167V3	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
PropylParaben	INACTIVE INGREDIENT	Z8IX2SC1OH	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Sodium lauryl Sulfate	INACTIVE INGREDIENT	368GB5141J	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
TROLAMINE	INACTIVE INGREDIENT	9O3K93S3TK	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Water	INACTIVE INGREDIENT	059QF0KO0R	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
76420-450	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ASCLEMED USA, INC]	6	Current NDC, Legacy NDC, 1 package rows	20231016_bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 29 of 152 · 3,029 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Walgreens Burn Pad	BURN PAD	Walgreens	3f8d7624-cf1e-1992-e063-6294a90a3806	2026-03-17	Boxed warning, Warnings	Exact identifier application number: M017
Hydrocortisone	HYDROCORTISONE	Mericon Industries	8f351b04-8f6d-4353-9100-13a8a80d656a	2026-03-17	Warnings	Exact identifier application number: M017
Shoe Pain Relief	LIDOCAINE HCI 4%	Sole Amie	0f2ccd5f-b9f4-40fc-b82f-173b0f19bf40	2026-03-16	Warnings	Exact identifier application number: M017
CVS Muscle Balm	MENTHOL, CAMPHOR	CVS Health	42796fc4-03be-3b02-e063-6394a90af2ab	2026-03-16	Warnings	Exact identifier application number: M017
Crane Safety Hydrocortisone	HYDROCORTISONE	Crane Safety LLC	96d9527d-9bf7-ce82-e053-2995a90aff0c	2026-03-16	Warnings	Exact identifier application number: M017
CVS Health Pain Relief Foot	MENTHOL, UNSPECIFIED FORM	NATURAL ESSENTIALS, INC.	0f646876-69d0-49db-ade2-2b3eb26dd399	2026-03-16	Warnings	Exact identifier application number: M017
Walgreens Cold Therapy Pain Relief Foot Cream	MENTHOL	Walgreen Co.	3bc8ece3-d555-3efb-e063-6394a90a1981	2026-03-16	Warnings	Exact identifier application number: M017
RICHTOFIT RAPID ACTIVE LEG AND FOOT	MENTHOL	RICHTOFIT LIMITED LIABILITY COMPANY	4c357696-ca96-e6ad-e063-6294a90aaadb	2026-03-16	Warnings	Exact identifier application number: M017
Xpect Stopain Clinical	MENTHOL	Cintas Corporation	348e6062-b31e-435e-a153-6aa868b50efa	2026-03-13	Warnings	Exact identifier application number: M017
DGH GREASELESS MUSCLE RUB ANALGESIC	MENTHOL, UNSPECIFIED FORM AND METHYL SALICYLATE	DOLLAR GENERAL	225abfe0-ec72-4667-96b2-7657e989672b	2026-03-13	Warnings	Exact identifier application number: M017
CVS Professional Pain Relief	MENTHOL	CVS Pharmacy	48836a5b-0baa-b7ee-e063-6294a90ac12b	2026-03-13	Warnings	Exact identifier application number: M017
Keeps Climax Delay	LIDOCAINE HYDROCHLORIDE	Cosco International, Inc.	3bfd3173-2dac-40a9-aec3-982b1d47d8fa	2026-03-12	Warnings	Exact identifier application number: M017
NanoX Pain Relieving	MENTHOL, METHYL SALICYLATE	MG Science Technologies LLC	4cc38927-8a8c-2df3-e063-6294a90aa0c1	2026-03-12	Warnings	Exact identifier application number: M017
Hand Sanitizer	ALCOHOL	ProStat First Aid	4cd4c51c-88bb-3797-e063-6294a90a8f70	2026-03-12	Warnings	Exact identifier application number: M017
CVS Lidocaine Pain Relief	LIDOCAINE HYDROCHLORIDE, MENTHOL	CVS Pharmacy	48c045ae-56b5-62c2-e063-6394a90aaf44	2026-03-12	Warnings	Exact identifier application number: M017
Hydrocortisone 1%	HYDROCORTISONE	ProStat First Aid	4cd62cba-075a-7448-e063-6394a90ab48d	2026-03-12	Warnings	Exact identifier application number: M017
Medicated Pain Relief Patch	CAMPHOR, MENTHOL, METHYL SALICYLATE	Kroger Company	47cc4b05-a937-4624-bf41-85b8bd7c049e	2026-03-12	Warnings	Exact identifier application number: M017
Lidocaine HCL	LIDOCAINE HCL	Matthias Therapeutics, LLC	4cdb27b5-9178-0328-e063-6394a90a50b5	2026-03-12	Warnings	Exact identifier application number: M017
RICHTOFIT RAPID ACTIVE ARTHRITIS	MENTHOL AND CAMPHOR	RICHTOFIT LIMITED LIABILITY COMPANY	4b1cdab1-3e50-4ec3-e063-6394a90af75e	2026-03-12	Warnings	Exact identifier application number: M017
5Kind DMSO 4 Lidocaine HCl Pain Relieving	LIDOCAINE HYDROCHLORIDE, MENTHOL	5KIND TRADING LTD	67d8d045-7fa0-46c2-8072-645d8823903b	2026-03-11	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
LAV5U5022Y	METHYL SALICYLATE	119-36-8	METHYL SALICYLATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	PSN	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 30 MG/ML / methyl salicylate 100 MG/ML Topical Cream	SCD	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	SY	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	PSN	0b7736df-c7e0-7d00-e063-6294a90aa57e	2
1486874	menthol 30 MG/ML / methyl salicylate 100 MG/ML Topical Cream	SCD	0b7736df-c7e0-7d00-e063-6294a90aa57e	2
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	SY	0b7736df-c7e0-7d00-e063-6294a90aa57e	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
76420-450-12	76420045012	113 g in 1 BOTTLE (76420-450-12)	113 g	2014-01-15	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Calypxo Cream	Advanced Rx of Tennessee, LLC	2024-12-31	HUMAN OTC DRUG LABEL	2
Calypxo Pain Relief - Asclemed USA, Inc	Asclemed USA, Inc	2023-10-16	HUMAN OTC DRUG LABEL	6
CALYPXO CREAM 10% / 3% 4 OZ	DirectRX	2023-07-20	HUMAN OTC DRUG LABEL	2