Calypxo Pain Relief

Product NDC: 76420-450
11-digit product format: 764200450
Labeler code: 76420
Product ID: 76420-450_07cec8ef-ecc9-ac49-e063-6294a90a6083
Type: HUMAN OTC DRUG
Nonproprietary name: Methyl Salicylate, Menthol
Dosage form: CREAM
Route: TOPICAL
Labeler: Asclemed USA, Inc
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2014-01-15
Substance: METHYL SALICYLATE; MENTHOL
Active strength: 10; 3 g/100g; g/100g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Calypxo Pain Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
METHYL SALICYLATE	10 g/100g
MENTHOL	3 g/100g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
LAV5U5022Y	Internal UNII lookup
L7T10EIP3A	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1486874	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
76420-450-12	Calypxo Pain Relief	113 g in 1 BOTTLE	CREAM	113		6

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
76420-450-12	GM - Gram	76420-450	e387b485-2d49-4f5c-bfa1-3c2fa94acbe0	1	2014-02-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Menthol	ACTIVE INGREDIENT	L7T10EIP3A	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Methyl Salicylate	ACTIVE INGREDIENT	LAV5U5022Y	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Menthol	ACTIVE MOIETY	L7T10EIP3A	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
SALICYLIC ACID	ACTIVE MOIETY	O414PZ4LPZ	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Aloe Vera Leaf	INACTIVE INGREDIENT	ZY81Z83H0X	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
CARBOMER INTERPOLYMER TYPE A (ALLYL SUCROSE CROSSLINKED)	INACTIVE INGREDIENT	59TL3WG5CO	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Cetyl Alcohol	INACTIVE INGREDIENT	936JST6JCN	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Diazolidinyl Urea	INACTIVE INGREDIENT	H5RIZ3MPW4	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Isopropyl Myristate	INACTIVE INGREDIENT	0RE8K4LNJS	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
MethylParaben	INACTIVE INGREDIENT	A2I8C7HI9T	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
POLYETHYLENE GLYCOL 400	INACTIVE INGREDIENT	B697894SGQ	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Propylene Glycol	INACTIVE INGREDIENT	6DC9Q167V3	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
PropylParaben	INACTIVE INGREDIENT	Z8IX2SC1OH	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Sodium lauryl Sulfate	INACTIVE INGREDIENT	368GB5141J	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
TROLAMINE	INACTIVE INGREDIENT	9O3K93S3TK	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2
Water	INACTIVE INGREDIENT	059QF0KO0R	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ENOVACHEM MANUFACTURING]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
76420-450	CALYPXO PAIN RELIEF (METHYL SALICYLATE, MENTHOL) CREAM [ASCLEMED USA, INC]	6	Current NDC, Legacy NDC, 1 package rows	20231016_bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 81 of 151 · 3,010 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
LILAS PERIOD	MENTHOL	Lilas Wellness, Inc.	5ea53b4b-45e6-48a7-8090-09c3a21e7f63	2025-08-11	Warnings	Exact identifier application number: M017
Lidocaine Pain Relief Gel Roll-On	LIDOCAINE	Guangzhou Zhupuyou E-commerce Co., Ltd	31639407-0f11-bde2-e063-6294a90af694	2025-08-10	Warnings	Exact identifier application number: M017
Chinese Red Tiger Lidocaine Patches	LIDOCAINE	Guangzhou Zhupuyou E-commerce Co., Ltd	20cd369c-3e98-3d8f-e063-6394a90a0824	2025-08-10	Warnings	Exact identifier application number: M017
Treatonic LIDOCAINE PAIN RELIEF	LIDOCAINE 4%	100 KARMA INC	3bd66b03-ac82-2d45-e063-6294a90a610a	2025-08-08	Warnings	Exact identifier application number: M017
Capsaicin 0.025%	CAPSAICIN 0.025%	Advanced Rx of Tennessee, LLC	3bdcef94-d06f-9152-e063-6294a90a6072	2025-08-08	Warnings	Exact identifier application number: M017
MENTHOL 5%	MENTHOL 5%	Advanced Rx of Tennessee, LLC	3bdd0c52-29d8-ab67-e063-6294a90a9c45	2025-08-08	Warnings	Exact identifier application number: M017
Methyl Salicylate 25% Cream	METHYL SALICYLATE	Advanced Rx of Tennessee, LLC	3bdd3015-349a-0fac-e063-6394a90afe41	2025-08-08	Warnings	Exact identifier application number: M017
LIDOCAINE 4%	LIDOCAINE 4%	Advanced Rx of Tennessee, LLC	3bdd6b3d-7180-288c-e063-6394a90a1785	2025-08-08	Warnings	Exact identifier application number: M017
Good Sense Pain Relief Roll On	LIDOCAINE HCL	Geiss, Destin & Dunn, Inc	38e76fd6-e5fb-493c-e063-6294a90afed4	2025-08-08	Warnings	Exact identifier application number: M017
Aruba Aloe Alcoholada	LIDOCAINE HYDROCHLORIDE	Aruba Aloe Balm NV	f56c62b0-75db-4499-858e-54e10b0e140a	2025-08-07	Warnings	Exact identifier application number: M017
SurviveX Hydrocortisone Cream	HYDROCORTISONE	Nantong Health & Beyond Hygienic Products Inc.	3bd1da8d-5142-798c-e063-6294a90a7be6	2025-08-07	Warnings	Exact identifier application number: M017
Arthcal SOOTHING PAIN RELIEF MASSAGE	SOOTHING PAIN RELIEF MASSAGE	Beijing JUNGE Technology Co., Ltd.	3524ad62-0ed6-f2e5-e063-6394a90a3283	2025-08-06	Warnings	Exact identifier application number: M017
Alumier MD Intensive Recovery	HYDROCORTISONE	Alumier Labs	d9b79ea1-6558-543c-e053-2995a90ae53e	2025-08-06	Warnings	Exact identifier application number: M017
Good Neighbor Roll-on Pain Relief	LIDOCAINE HCL	Amerisource Bergen	a0c3adbf-fa35-47c0-9db3-459ce9a106ac	2025-08-06	Warnings	Exact identifier application number: M017
Good Neighbor Roll-on Menthol Pain Relief Gel	MENTHOL	Amerisource Bergen	bd557323-0003-4ee6-b22d-a72d621c7de4	2025-08-05	Warnings	Exact identifier application number: M017
Earthmed FS Pain relieving balm	MENTHOL	Earthmed LLC	3ba4e769-fec6-52d9-e063-6394a90a65d4	2025-08-05	Warnings	Exact identifier application number: M017
HYDROCORTISONE	HYDROCORTISONE	HF Acquisition Co LLC, DBA HealthFirst	3ba6a5ec-fda2-b2a6-e063-6294a90ac9b6	2025-08-05	Warnings	Exact identifier application number: M017
Kocowo Lidocaine Pain Relief Gel-Patch	LIDOCAINE PAIN RELIEF GEL-PATCH	Henan Enokon Medical Instrument Co., Ltd.	3b82989d-7cc3-23d3-e063-6294a90ae2a3	2025-08-03	Warnings	Exact identifier application number: M017
Menthol pain relief patches	MENTHOL	Menthol pain relief patch	3b5fd718-3f86-f7a7-e063-6294a90a8c52	2025-08-02	Warnings	Exact identifier application number: M017
Graphene Far Infrared Herbal Pain Relief Patches	CORYDALIS RHIZOME	Changsha Maocheng Trading Co., Ltd	3b604a3c-fe91-7096-e063-6394a90afe04	2025-08-02	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
LAV5U5022Y	METHYL SALICYLATE	119-36-8	METHYL SALICYLATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	PSN	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 30 MG/ML / methyl salicylate 100 MG/ML Topical Cream	SCD	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	SY	bd9d0bc0-5705-4c73-bcd6-f6cdb68e05b6	6
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	PSN	0b7736df-c7e0-7d00-e063-6294a90aa57e	2
1486874	menthol 30 MG/ML / methyl salicylate 100 MG/ML Topical Cream	SCD	0b7736df-c7e0-7d00-e063-6294a90aa57e	2
1486874	menthol 3 % / methyl salicylate 10 % Topical Cream	SY	0b7736df-c7e0-7d00-e063-6294a90aa57e	2

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
76420-450-12	76420045012	113 g in 1 BOTTLE (76420-450-12)	113 g	2014-01-15	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Calypxo Cream	Advanced Rx of Tennessee, LLC	2024-12-31	HUMAN OTC DRUG LABEL	2
Calypxo Pain Relief - Asclemed USA, Inc	Asclemed USA, Inc	2023-10-16	HUMAN OTC DRUG LABEL	6
CALYPXO CREAM 10% / 3% 4 OZ	DirectRX	2023-07-20	HUMAN OTC DRUG LABEL	2