Simlandi Purple Book BLA 761299

BLA number
761299
Proprietary names
Simlandi
Proper names
adalimumab-ryvk
Applicant
Alvotech USA Inc.
Center
CDER
First observed release
2024-02-01
Latest observed release
2026-06-01
Newest archive release
2026-06-01
FDA patent list
No patents listed in the captured FDA patent list; source updated 2025-06-11
Coverage
Present in newest release

Latest Known Product Presentations#

Product, Proprietary name, Proper name table
ProductProprietary nameProper nameLicense typeStrengthDosage formRoutePresentationMarketingLicensureApprovalPatent list provided
001Simlandiadalimumab-ryvk351(k) Interchangeable40MG/0.4MLInjectionSubcutaneousAutoinjectorRxLicensed2024-02-23
002Simlandiadalimumab-ryvk351(k) Interchangeable40MG/0.4MLInjectionSubcutaneousPre-Filled SyringeRxLicensed2024-06-26
003Simlandiadalimumab-ryvk351(k) Interchangeable20MG/0.2MLInjectionSubcutaneousPre-Filled SyringeRxLicensed2024-06-26
004Simlandiadalimumab-ryvk351(k) Interchangeable80MG/0.8MLInjectionSubcutaneousPre-Filled SyringeRxLicensed2024-06-26
005Simlandiadalimumab-ryvk351(k) Interchangeable80MG/0.8MLInjectionSubcutaneousAutoinjectorRxLicensed2025-02-14

Reference Biological Product#

BLA, Proprietary name, Proper name table
BLAProprietary nameProper nameLicense typeStatusLatest source
125057Humiraadalimumab351(a)Rx2026-06-01

Published Patent List#

No patents for this BLA were listed in the FDA Purple Book patent list captured from the source updated 2025-06-11.

Official Monthly Change Events#

Release, Event, Product table
ReleaseEventProductNameLicense typeStatusApplicant
2025-04-01U003Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2025-04-01U004Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2025-04-01U005Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2025-03-01N005Simlandi351(k) BiosimilarRxAlvotech USA Inc.
2024-08-01U001Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2024-08-01U002Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2024-07-01N002Simlandi351(k) InterchangeableRxAlvotech USA Inc.
2024-07-01N003Simlandi351(k) BiosimilarRxAlvotech USA Inc.
2024-07-01N004Simlandi351(k) BiosimilarRxAlvotech USA Inc.
2024-02-01N001Simlandi351(k) InterchangeableRxAlvotech USA Inc.

Observed Product State History#

Release, Product, Name table
ReleaseProductNameLicense typeMarketingLicensureApproval
2025-04-01003Simlandi351(k) InterchangeableRxLicensed2024-06-26
2025-04-01004Simlandi351(k) InterchangeableRxLicensed2024-06-26
2025-04-01005Simlandi351(k) InterchangeableRxLicensed2025-02-14
2025-03-01005Simlandi351(k) BiosimilarRxLicensed2025-02-14
2024-07-01002Simlandi351(k) InterchangeableRxLicensed2024-06-26
2024-07-01003Simlandi351(k) BiosimilarRxLicensed2024-06-26
2024-07-01004Simlandi351(k) BiosimilarRxLicensed2024-06-26
2024-02-01001Simlandi351(k) InterchangeableRxLicensed2024-02-23