Application 018936

Type
NDA
Sponsor
ELI LILLY AND CO

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001PROZACFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 20MG BASEYesNo
003PROZACFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 40MG BASEYesYes
004PROZACFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 60MG BASENoNo
006PROZACFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 10MG BASEYesNo
007SARAFEMFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
008SARAFEMFLUOXETINE HYDROCHLORIDECAPSULE;ORALEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N018936-001PROZACFLUOXETINE HYDROCHLORIDEEQ 20MG BASECAPSULE / ORALRLD1987-12-29
N018936-003PROZACFLUOXETINE HYDROCHLORIDEEQ 40MG BASECAPSULE / ORALRLD1999-06-15
N018936-004PROZACFLUOXETINE HYDROCHLORIDEEQ 60MG BASECAPSULE / ORAL1999-06-15
N018936-006PROZACFLUOXETINE HYDROCHLORIDEEQ 10MG BASECAPSULE / ORALRLD1992-12-23
N018936-007SARAFEMFLUOXETINE HYDROCHLORIDEEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06
N018936-008SARAFEMFLUOXETINE HYDROCHLORIDEEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N018936-001PROZACEQ 20MG BASECAPSULE / ORALRLD1987-12-29caaa826d4ba7…
2026-08-18 06:07:402026-07N018936-003PROZACEQ 40MG BASECAPSULE / ORALRLD1999-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N018936-006PROZACEQ 10MG BASECAPSULE / ORALRLD1992-12-23caaa826d4ba7…
2026-08-18 06:07:402026-07N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06caaa826d4ba7…
2026-08-18 06:07:402026-07N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-0631067a03dcf5…
2025-08-23 18:47 UTC2025-08N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-066a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-007SARAFEMEQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-008SARAFEMEQ 20MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**CAPSULE / ORALRLD2000-07-06b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-001PROZACEQ 20MG BASECAPSULE / ORALAB1RLD1987-12-2903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-003PROZACEQ 40MG BASECAPSULE / ORALABRLD, RS1999-06-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-004PROZACEQ 60MG BASECAPSULE / ORAL1999-06-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-006PROZACEQ 10MG BASECAPSULE / ORALAB1RLD1992-12-2303ed91905a0d…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 120 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N018936-001AB11011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N018936-006AB11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-001AB1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N018936-006AB1131067a03dcf5…
2025-08-23 18:47 UTC2025-08N018936-001AB116a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N018936-006AB116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-001AB11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N018936-006AB11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-001AB11b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N018936-006AB11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-001AB1103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N018936-006AB1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018936-001AB112680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018936-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N018936-006AB112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N018936-001AB115bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N018936-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N018936-006AB115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N018936-001AB11d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N018936-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N018936-006AB11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N018936-001AB11d06236e962d9…
2024-10-29 15:01 UTC2024-10N018936-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N018936-006AB11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N018936-001AB1179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N018936-003AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N018936-006AB1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N018936-001AB11301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N018936-003AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N018936-006AB11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N018936-001AB111e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N018936-003AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N018936-006AB111e350fbaab3a…
2024-05-31 18:47 UTC2024-05N018936-001AB118072bd15b7f6…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ProzacFLUOXETINE HYDROCHLORIDEDista Products Companyc88f33ed-6dfb-4c5e-bc01-d8e36dd972992026-01-08Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 018936
application number: NDA018936
ndc (product): 0777-3104
ndc (product): 0777-3105
ndc (product): 0777-3107

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 16 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0777-3104ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3104ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3104ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3104ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3104ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3105ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3105ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3105ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3105ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3105ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3107ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3107ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3107ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3107ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
0777-3107ProzacFluoxetine hydrochlorideDista Products CompanyNDACurrent
70518-2101ProzacFluoxetine hydrochlorideREMEDYREPACK INC.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
78575SUPPL 2024-05-29
78425SUPPL 2024-05-08
75234SUPPL 2023-08-22
75197SUPPL 2023-08-22
75196SUPPL 2023-08-22
68970SUPPL2021-10-13
68911SUPPL2021-10-07
62738SUPPL2020-04-29
62737SUPPL2020-04-29
62733SUPPL2020-04-29
47757SUPPL2017-03-29
47720SUPPL2017-03-27
47719SUPPL2017-03-27
46818SUPPL2017-01-13
46698SUPPL2017-01-06
16122SUPPL2015-11-25
20169SUPPL2015-11-18
40831SUPPL2015-11-05
16120SUPPL2014-10-15
11380SUPPL2014-10-15
16121SUPPL2014-07-24
33668SUPPL2014-07-23
20168SUPPL2013-10-21
33667SUPPL2013-07-30
16119SUPPL2013-07-30
11379SUPPL2013-07-30
1146SUPPL2013-07-30
33666SUPPL2013-01-07
33665SUPPL2013-01-07
16118SUPPL2013-01-07
1145SUPPL2013-01-07
33664SUPPL2011-06-16
16117SUPPL2011-06-16
16116SUPPL2011-04-13
1144SUPPL2011-04-13
1143SUPPL2011-04-13
33663SUPPL2011-04-04
33662SUPPL2011-04-04
11378SUPPL2011-04-04
33661SUPPL2009-06-24
16115SUPPL2009-06-24
16110SUPPL2009-03-24
1139SUPPL2009-03-24
33658SUPPL2009-03-20
11372SUPPL2009-03-20
11377SUPPL2009-02-04
16114SUPPL2009-02-03
16113SUPPL2008-07-01
11376SUPPL2008-06-30
11375SUPPL2008-03-24
1142SUPPL2008-03-24
33660SUPPL2008-03-13
16112SUPPL2008-03-12
40828SUPPL2007-12-06
16111SUPPL2007-08-07
1141SUPPL2007-08-07
11374SUPPL2007-08-03
11373SUPPL2007-08-03
1140SUPPL2007-03-23
20166SUPPL2007-02-20
20165SUPPL2007-02-20
20164SUPPL2007-02-20
33659SUPPL2006-09-21
16109SUPPL2006-04-13
16107SUPPL2005-12-05
1138SUPPL2005-12-05
23544ORIG2005-08-01
16108SUPPL2005-02-23
1137SUPPL2004-09-03
1136SUPPL2004-08-25
40830SUPPL2004-08-09
20163SUPPL2004-08-09
40829SUPPL2003-09-25
20167SUPPL2003-09-25
16105SUPPL2003-01-07
11371SUPPL2003-01-07
33656SUPPL2002-07-29
33657SUPPL2002-06-12
16106SUPPL2002-06-12
11370SUPPL2000-07-06
1135SUPPL2000-07-06