Application 020281

Type: NDA
Sponsor: JANSSEN PHARMS

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	ULTRAM	TRAMADOL HYDROCHLORIDE	TABLET;ORAL	100MG	No	No
002	ULTRAM	TRAMADOL HYDROCHLORIDE	TABLET;ORAL	50MG	Yes	Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N020281-001	ULTRAM	TRAMADOL HYDROCHLORIDE	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03
N020281-002	ULTRAM	TRAMADOL HYDROCHLORIDE	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N020281-002	ULTRAM	50MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL		RLD	1995-03-03	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020281-001	ULTRAM	100MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons	TABLET / ORAL			1995-03-03	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020281-001	ULTRAM	100MG	TABLET / ORAL			1995-03-03	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020281-001	ULTRAM	100MG	TABLET / ORAL			1995-03-03	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020281-001	ULTRAM	100MG	TABLET / ORAL			1995-03-03	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020281-001	ULTRAM	100MG	TABLET / ORAL			1995-03-03	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020281-001	ULTRAM	100MG	TABLET / ORAL			1995-03-03	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N020281-002	ULTRAM	50MG	TABLET / ORAL	AB	RLD, RS	1995-03-03	`782e0a99824c…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020281-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020281-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020281-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020281-002	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020281-002	AB	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020281-002	AB	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N020281-002	AB	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N020281-002	AB	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N020281-002	AB	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020281-002	AB	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020281-002	AB	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020281-002	AB	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020281-002	AB	1	`ea99ee380514…`
2022-09-29 23:25 UTC	2022-09	N020281-002	AB	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N020281-002	AB	1	`cb3db0bc1861…`

Observed Orange Book patent history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N020281-001	6339105	2019-10-12	U-435		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N020281-002	6339105	2019-10-12	U-435		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`74a2ff9319b5…`
2020-12-22 03:56 UTC	2020-12	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020281-001	6339105	2019-10-12	U-435		`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N020281-002	6339105	2019-10-12	U-435		`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020281-001	6339105	2019-10-12	U-435		`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N020281-002	6339105	2019-10-12	U-435		`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020281-001	6339105	2019-10-12	U-435		`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N020281-001	6339105*PED	2020-04-12		Pediatric extension	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N020281-002	6339105	2019-10-12	U-435		`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N020281-002	6339105*PED	2020-04-12		Pediatric extension	`ea99ee380514…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 5 · 92 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	REMEDYREPACK INC.	9f0e33bd-65f8-446a-886f-e7e16a142ce5	2026-07-30	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	REMEDYREPACK INC.	16053b28-c759-4914-93e6-2de0afe72445	2026-07-02	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	St. Mary's Medical Park Pharmacy	42de8c3a-0441-5d46-e063-6294a90a2079	2026-07-02	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	REMEDYREPACK INC.	6bb5be12-59ff-40f4-9841-9c7ab93be2ea	2026-07-01	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Advanced Rx of Tennessee, LLC	552e5b32-accf-29dd-e063-6294a90a4fcf	2026-06-26	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Northwind Health Company, LLC	552955e6-2bb3-8755-e063-6394a90ab21c	2026-06-25	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Coupler LLC	54d74939-301b-e603-e063-6394a90a3b03	2026-06-22	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	515baa9a-b226-4bbe-be87-f9befdf1c9e1	2026-06-18	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	REMEDYREPACK INC.	5199132e-745e-46a0-8068-e06d1bca5c61	2026-06-15	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Preferred Pharmaceuticals Inc.	855905c7-1481-4b2d-a318-3254ad8ed73c	2026-06-08	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Proficient Rx LP	aefc85bc-0820-4aee-8d94-313c5f1658f5	2026-06-01	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Major Pharmaceuticals	6b0b95b2-ae4c-42e8-9f2e-bcdaffda62e2	2026-05-28	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	66359f41-9999-4cb8-b632-1fe2ec1e60b2	2026-05-13	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	43fe10b2-17a4-4dc2-9a48-2378547b61fd	2026-05-13	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	ST. MARY'S MEDICAL PARK PHARMACY	f2f421ab-35ae-7637-e053-2995a90a40e0	2026-05-01	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	674803a0-4cf5-4416-a5e3-c1a1e332cdcd	2026-04-13	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	acd5d8e0-a4cc-4654-ae04-faff347a60ca	2026-04-13	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
Tramadol Hydrochloride	TRAMADOL HYDROCHLORIDE	Unichem Pharmaceuticals (USA), Inc.	007bf37f-0e46-426a-ac8c-be63d4b7414c	2026-04-10	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	Bryant Ranch Prepack	a77b0dba-8ac7-418a-b435-16a0e6c22804	2026-04-07	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE
TRAMADOL HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE	REMEDYREPACK INC.	b76c1366-f6c0-42ad-bb19-2b72a91490e4	2026-03-30	Boxed warning, Warnings, Adverse reactions	Name fallback generic name: TRAMADOL HYDROCHLORIDE

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 7 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals,	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current
50458-659	ULTRAM	tramadol hydrochloride	Janssen Pharmaceuticals, Inc.	NDA	Current

Documents#

Document, Submission type, Date table
Document	Submission type	Date
76230	ORIG	2023-11-03
73501	SUPPL	2023-02-14
73500	SUPPL	2023-02-14
73491	SUPPL	2023-02-14
68609	SUPPL	2021-09-14
68608	SUPPL	2021-09-13
68607	SUPPL	2021-09-13
66585	SUPPL	2021-03-08
66584	SUPPL	2021-03-08
66506	SUPPL	2021-03-05
60342	SUPPL	2019-10-08
60327	SUPPL	2019-10-08
60326	SUPPL	2019-10-08
58278	SUPPL	2019-04-10
58263	SUPPL	2019-04-09
57644	ORIG	2019-02-15
55875	SUPPL	2018-10-11
55874	SUPPL	2018-10-11
55679	SUPPL	2018-10-01
55678	SUPPL	2018-10-01
49625	SUPPL	2017-08-30
49595	SUPPL	2017-08-30
46386	SUPPL	2016-12-21
46385	SUPPL	2016-12-21
46252	SUPPL	2016-12-20
46251	SUPPL	2016-12-20
24731	SUPPL	2009-11-12
24730	SUPPL	2009-11-12
34472	SUPPL	2009-10-06
12419	SUPPL	2009-10-06
24728	SUPPL	2004-06-29
24727	SUPPL	2004-06-29
34471	SUPPL	2004-05-03
2293	SUPPL	2004-04-20
20585	SUPPL	2003-08-07
20584	SUPPL	2003-08-07
34470	SUPPL	2003-04-22
34469	SUPPL	1999-12-23
24729	SUPPL	1999-12-23