Application 020386

Type
NDA
Sponsor
MERCK SHARP DOHME

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001COZAARLOSARTAN POTASSIUMTABLET;ORAL25MGYesNo
002COZAARLOSARTAN POTASSIUMTABLET;ORAL50MGYesNo
003COZAARLOSARTAN POTASSIUMTABLET;ORAL100MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020386-001COZAARLOSARTAN POTASSIUM25MGTABLET / ORALABRLD1995-04-14
N020386-002COZAARLOSARTAN POTASSIUM50MGTABLET / ORALABRLD1995-04-14
N020386-003COZAARLOSARTAN POTASSIUM100MGTABLET / ORALABRLD, RS1998-10-13

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N020386-001AB
N020386-002AB
N020386-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14caaa826d4ba7…
2026-08-18 06:07:402026-07N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14caaa826d4ba7…
2026-08-18 06:07:402026-07N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-002COZAAR50MGTABLET / ORALABRLD1995-04-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-003COZAAR100MGTABLET / ORALABRLD, RS1998-10-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020386-001COZAAR25MGTABLET / ORALABRLD1995-04-141e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 110 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N020386-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N020386-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N020386-003AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020386-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020386-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020386-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020386-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020386-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020386-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020386-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020386-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020386-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020386-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020386-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020386-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020386-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020386-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N020386-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N020386-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020386-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020386-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020386-001AB11e350fbaab3a…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
COZAARLOSARTAN POTASSIUMOrganon LLC9949448f-c3b9-44ee-94ed-c1aca8c90f392026-01-20Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 020386
application number: NDA020386
ndc (product): 78206-122
ndc (product): 78206-121
ndc (product): 78206-123

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 30 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0006-0951COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0951COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0951COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0951COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0952COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0952COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0952COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0952COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0960COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0960COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0960COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0006-0960COZAARlosartan potassiumMerck Sharp & Dohme Corp.NDACurrent
0781-5805Losartan Potassiumlosartan potassiumSandoz Inc.NDACurrent
0781-5806Losartan Potassiumlosartan potassiumSandoz Inc.NDACurrent
0781-5807Losartan Potassiumlosartan potassiumSandoz Inc.NDACurrent
55289-238COZAARlosartan potassiumPD-Rx Pharmaceuticals, InNDACurrent
55289-238COZAARlosartan potassiumPD-Rx Pharmaceuticals, Inc.NDACurrent
55289-238COZAARlosartan potassiumPD-Rx Pharmaceuticals, Inc.NDACurrent
55289-238COZAARlosartan potassiumPD-Rx Pharmaceuticals, Inc.NDACurrent
55289-238COZAARlosartan potassiumPD-Rx Pharmaceuticals, Inc.NDACurrent
63629-2912COZAARlosartan potassiumBryant Ranch PrepackNDACurrent
78206-121COZAARlosartan potassiumOrganon LLCNDACurrent
78206-121COZAARlosartan potassiumOrganon LLCNDACurrent
78206-121COZAARlosartan potassiumOrganon LLCNDACurrent
78206-122COZAARlosartan potassiumOrganon LLCNDACurrent
78206-122COZAARlosartan potassiumOrganon LLCNDACurrent
78206-122COZAARlosartan potassiumOrganon LLCNDACurrent
78206-123COZAARlosartan potassiumOrganon LLCNDACurrent
78206-123COZAARlosartan potassiumOrganon LLCNDACurrent
78206-123COZAARlosartan potassiumOrganon LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82680SUPPL 2025-06-27
82662SUPPL 2025-06-25
69065SUPPL2021-10-22
69041SUPPL2021-10-21
55965SUPPL2018-10-17
55911SUPPL2018-10-15
12512SUPPL2015-12-15
2447SUPPL2015-12-15
2452SUPPL2014-10-01
12515SUPPL2014-09-30
12514SUPPL2014-01-22
2451SUPPL2014-01-21
12513SUPPL2013-04-01
2450SUPPL2013-03-29
2449SUPPL2012-10-03
34590SUPPL2012-10-02
44056ORIG2011-12-22
34589SUPPL2011-11-21
2448SUPPL2011-11-21
24885SUPPL2011-06-17
24884SUPPL2010-09-27
34588SUPPL2010-09-23
24883SUPPL2009-06-16
34587SUPPL2009-06-04
24882SUPPL2006-09-25
24881SUPPL2006-09-25
24136SUPPL2006-09-25
24135SUPPL2006-09-25
2446SUPPL2006-09-18
12511SUPPL2006-08-30
43561SUPPL2006-04-14
2445SUPPL2006-04-07
24880SUPPL2005-04-13
12510SUPPL2005-04-13
12509SUPPL2005-04-13
2444SUPPL2005-04-13
20622SUPPL2005-02-02
41318SUPPL2004-06-04
41320SUPPL2004-06-02
34586SUPPL2004-05-06
34585SUPPL2004-05-06
2442SUPPL2004-03-16
2440SUPPL2004-03-16
41321SUPPL2003-07-08
2443SUPPL2003-03-28
12508SUPPL2003-03-25
12507SUPPL2002-09-17
2441SUPPL2002-09-17
41319SUPPL2001-06-06
41317SUPPL2000-01-28
41316SUPPL1999-06-09
20621SUPPL1998-11-24
41315SUPPL1998-10-13
20620SUPPL1997-11-07
57423ORIG1996-03-16