Application 021073

Type
NDA
Sponsor
TAKEDA PHARMS USA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ACTOSPIOGLITAZONE HYDROCHLORIDETABLET;ORALEQ 15MG BASEYesNo
002ACTOSPIOGLITAZONE HYDROCHLORIDETABLET;ORALEQ 30MG BASEYesNo
003ACTOSPIOGLITAZONE HYDROCHLORIDETABLET;ORALEQ 45MG BASEYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021073-001ACTOSPIOGLITAZONE HYDROCHLORIDEEQ 15MG BASETABLET / ORALABRLD1999-07-15
N021073-002ACTOSPIOGLITAZONE HYDROCHLORIDEEQ 30MG BASETABLET / ORALABRLD1999-07-15
N021073-003ACTOSPIOGLITAZONE HYDROCHLORIDEEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N021073-001AB
N021073-002AB
N021073-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15d06236e962d9…
2024-10-29 15:01 UTC2024-10N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15d06236e962d9…
2024-10-29 15:01 UTC2024-10N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-002ACTOSEQ 30MG BASETABLET / ORALABRLD1999-07-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-003ACTOSEQ 45MG BASETABLET / ORALABRLD, RS1999-07-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021073-001ACTOSEQ 15MG BASETABLET / ORALABRLD1999-07-158072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021073-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021073-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021073-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021073-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021073-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021073-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021073-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021073-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021073-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021073-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021073-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021073-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021073-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021073-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021073-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021073-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021073-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021073-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021073-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021073-001AB18072bd15b7f6…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ActosPIOGLITAZONETakeda Pharmaceuticals America, Inc.d2ddc491-88a9-4063-9150-443b4fa4330c2025-03-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021073
application number: NDA021073
ndc (product): 64764-301
ndc (product): 64764-151
ndc (product): 64764-451

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 27 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
21695-147Actospioglitazone hydrochlorideRebel Distributors Corp.NDACurrent
21695-148Actospioglitazone hydrochlorideRebel Distributors Corp.NDACurrent
54458-884PioglitazonePioglitazoneInternational Laboratories, LLCNDA AUTHORIZED GENERICCurrent
54458-885PioglitazonePioglitazoneInternational Laboratories, LLCNDA AUTHORIZED GENERICCurrent
63304-311PioglitazonepioglitazoneRanbaxy Pharmaceuticals Inc.NDA AUTHORIZED GENERICCurrent
63304-312PioglitazonepioglitazoneRanbaxy Pharmaceuticals Inc.NDA AUTHORIZED GENERICCurrent
63304-313PioglitazonepioglitazoneRanbaxy Pharmaceuticals Inc.NDA AUTHORIZED GENERICCurrent
64764-151ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-151ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-151ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-151ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-301ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-301ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-301ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-301ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-451ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-451ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-451ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
64764-451ActospioglitazoneTakeda Pharmaceuticals America, Inc.NDACurrent
66116-504PioglitazonepioglitazoneMedVantx, Inc.NDA AUTHORIZED GENERICCurrent
68071-1621PioglitazonepioglitazoneNuCare Pharmaceuticals,Inc.NDA AUTHORIZED GENERICCurrent
68071-1621PioglitazonepioglitazoneNuCare Pharmaceuticals,Inc.NDA AUTHORIZED GENERICCurrent
68071-1621PioglitazonepioglitazoneNuCare Pharmaceuticals,Inc.NDA AUTHORIZED GENERICCurrent
68151-3792PioglitazonepioglitazoneCarilion Materials ManagementNDA AUTHORIZED GENERICCurrent
68151-3798PioglitazonepioglitazoneCarilion Materials ManagementNDA AUTHORIZED GENERICCurrent
68258-3034Actospioglitazone hydrochlorideDispensing Solutions, Inc.NDACurrent
68258-5230Actospioglitazone hydrochlorideDispensing Solutions, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
50915SUPPL2017-12-27
50864SUPPL2017-12-26
50863SUPPL2017-12-26
46170SUPPL2016-12-15
46137SUPPL2016-12-13
36020SUPPL2013-11-14
4217SUPPL2013-11-14
26646SUPPL2012-05-22
26645SUPPL2011-08-05
4216SUPPL2011-08-05
14292SUPPL2011-08-04
14291SUPPL2011-08-04
14289SUPPL2011-02-09
4215SUPPL2010-07-30
4214SUPPL2009-10-26
14290SUPPL2009-09-18
36019SUPPL2009-01-02
26644SUPPL2008-12-18
41929SUPPL2008-07-31
41928SUPPL2008-07-31
43567SUPPL2008-06-12
4213SUPPL2008-05-09
41926SUPPL2008-02-19
21414SUPPL2008-02-19
21411SUPPL2008-02-19
21410SUPPL2008-02-19
21408SUPPL2008-02-19
21416SUPPL2007-11-19
21415SUPPL2007-11-19
41924SUPPL2007-09-13
41923SUPPL2007-09-13
21409SUPPL2007-09-13
21407SUPPL2007-09-13
26643SUPPL2007-09-11
14288SUPPL2007-09-11
4212SUPPL2007-08-17
36018SUPPL2007-08-15
41925SUPPL2007-07-27
21412SUPPL2007-07-27
21413SUPPL2007-07-09
41927SUPPL2007-07-06
36015SUPPL2007-03-07
26641SUPPL2007-03-06
4211SUPPL2006-11-07
36017SUPPL2006-11-06
26642SUPPL2006-10-02
4210SUPPL2006-09-18
36016SUPPL2006-09-01
14286SUPPL2004-08-05
4208SUPPL2004-08-05
14287SUPPL2004-07-21
4209SUPPL2004-07-21
36014SUPPL2003-12-08
4207SUPPL2003-12-04
26640SUPPL2003-06-22
14285SUPPL2003-06-22
26639SUPPL2003-01-17
4206SUPPL2002-12-03
36013SUPPL2002-07-12
4204SUPPL2002-07-12
4205SUPPL2002-01-07
41922ORIG2000-06-30
26638ORIG1999-07-15
14284ORIG1999-07-15