Application 021782

Type
NDA
Sponsor
TAKEDA PHARMS USA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ROZEREMRAMELTEONTABLET;ORAL8MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021782-001ROZEREMRAMELTEON8MGTABLET / ORALABRLD, RS2005-07-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N021782-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-2274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-2287673890dc5c…
2021-03-12 10:30 UTC2021-03N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-223f01610625f2…
2019-09-15 20:21 UTC2019-09N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22b00525d2431f…
2019-07-19 19:46 UTC2019-07N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-229b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-223f0d92c62455…
2023-05-13 08:27 UTC2023-05N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22053a50430f4f…
2023-01-26 05:58 UTC2023-01N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-223bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-223a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021782-001ROZEREM8MGTABLET / ORALABRLD, RS2005-07-22cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021782-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021782-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021782-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021782-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021782-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021782-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021782-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021782-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021782-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021782-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021782-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021782-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021782-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021782-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021782-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021782-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021782-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021782-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021782-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021782-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021782-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N021782-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021782-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021782-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021782-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N021782-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N021782-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021782-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021782-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021782-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021782-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021782-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021782-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021782-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N021782-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N021782-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021782-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021782-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021782-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021782-001AB1cb3db0bc1861…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N021782-00160342392019-07-22U-674Drug substance, Drug product74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021782-001100988662021-11-16U-2433Drug product2018-11-0674a2ff9319b5…
2021-12-28 21:50 UTC2021-12N021782-001100988662021-11-16U-2433Drug product2018-11-06782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021782-001100988662021-11-16U-2433Drug product2018-11-0687673890dc5c…
2021-03-12 10:30 UTC2021-03N021782-001100988662021-11-16U-2433Drug product2018-11-065aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021782-001100988662021-11-16U-2433Drug product2018-11-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021782-001100988662021-11-16U-2433Drug product2018-11-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021782-00160342392019-07-22U-674Drug substance, Drug product3f01610625f2…
2019-12-14 00:12 UTC2019-12N021782-001100988662021-11-16U-2433Drug product2018-11-063f01610625f2…
2019-09-15 20:21 UTC2019-09N021782-00160342392019-07-22U-674Drug substance, Drug productb00525d2431f…
2019-09-15 20:21 UTC2019-09N021782-001100988662021-11-16U-2433Drug product2018-11-06b00525d2431f…
2019-07-19 19:46 UTC2019-07N021782-00160342392019-07-22U-674Drug substance, Drug productea99ee380514…
2019-07-19 19:46 UTC2019-07N021782-001100988662021-11-16U-2433Drug product2018-11-06ea99ee380514…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
RozeremRAMELTEONTakeda Pharmaceuticals America, Inc.9de82310-70e8-47b9-b1fc-6c6848b994552026-04-15Warnings, Adverse reactionsExact identifier
application applno (NDA): 021782
application number: NDA021782
ndc (product): 64764-805

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 8 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
21695-183RozeremramelteonRebel Distributors CorpNDACurrent
63629-3389RozeremramelteonBryant Ranch PrepackNDACurrent
63629-3389RozeremramelteonBryant Ranch PrepackNDACurrent
64764-805RozeremramelteonTakeda Pharmaceuticals America, Inc.NDACurrent
64764-805RozeremramelteonTakeda Pharmaceuticals America, Inc.NDACurrent
64764-805RozeremramelteonTakeda Pharmaceuticals America, Inc.NDACurrent
64764-805RozeremramelteonTakeda Pharmaceuticals America, Inc.NDACurrent
68151-4881RozeremramelteonCarilion Materials ManagementNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
69239SUPPL2021-11-05
69238SUPPL2021-11-05
69234SUPPL2021-11-05
57068SUPPL2018-12-30
57021SUPPL2018-12-26
57020SUPPL2018-12-26
28594SUPPL2012-03-05
6181SUPPL2012-03-05
6178SUPPL2012-03-05
28595SUPPL2011-08-05
28593SUPPL2010-11-15
37645SUPPL2010-11-12
23298SUPPL2010-11-12
37644SUPPL2008-11-07
16362SUPPL2008-11-07
16361SUPPL2008-11-07
28592SUPPL2008-10-23
6180SUPPL2008-10-23
6179SUPPL2008-10-23
42308ORIG2005-10-20
23676ORIG2005-08-30
37643SUPPL2005-08-23
28591SUPPL2005-08-23
37642ORIG2005-07-26
6177ORIG2005-07-26