Application 021825

Type
NDA
Sponsor
CHIESI

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001FERRIPROXDEFERIPRONETABLET;ORAL500MGYesYes
002FERRIPROXDEFERIPRONETABLET;ORAL1GMYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021825-001FERRIPROXDEFERIPRONE500MGTABLET / ORALRLD2011-10-14
N021825-002FERRIPROXDEFERIPRONE1GMTABLET / ORALABRLD2019-07-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N021825-002AB

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 6 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N021825-001ODE-4172028-04-30
N021825-001ODE-4202028-04-30
N021825-001ODE-4212028-04-30
N021825-002ODE-4172028-04-30
N021825-002ODE-4202028-04-30
N021825-002ODE-4212028-04-30

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 83 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021825-001FERRIPROX500MGTABLET / ORALRLD2011-10-14caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-141e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021825-001FERRIPROX500MGTABLET / ORALABRLD2011-10-148072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021825-001FERRIPROX500MGTABLET / ORALABRLD, RS2011-10-145c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021825-001FERRIPROX500MGTABLET / ORALABRLD, RS2011-10-145d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021825-001FERRIPROX500MGTABLET / ORALABRLD, RS2011-10-144b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021825-001FERRIPROX500MGTABLET / ORALRLD, RS2011-10-1474a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021825-002FERRIPROX1GMTABLET / ORALRLD2019-07-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021825-001FERRIPROX500MGTABLET / ORALABRLD, RS2011-10-14bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021825-002FERRIPROX1GMTABLET / ORALABRLD2019-07-25bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N021825-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021825-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021825-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021825-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021825-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021825-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021825-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021825-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021825-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021825-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021825-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021825-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021825-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021825-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021825-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021825-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021825-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021825-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021825-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021825-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021825-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021825-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021825-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021825-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021825-002AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N021825-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021825-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021825-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021825-001AB187673890dc5c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021825-001AB16a51e52b5d6a…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N021825-00170493282021-06-28U-7352015-10-0874a2ff9319b5…
2021-12-28 21:50 UTC2021-12N021825-00170493282021-06-28U-30832015-10-08782e0a99824c…
2021-12-28 21:50 UTC2021-12N021825-00270493282021-06-28U-30832020-01-31782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021825-00170493282021-06-28U-7352015-10-0887673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021825-00270493282021-06-28U-7352020-01-3187673890dc5c…
2021-03-12 10:30 UTC2021-03N021825-00170493282021-06-28U-7352015-10-085aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N021825-00270493282021-06-28U-7352020-01-315aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021825-00170493282021-06-28U-7352015-10-088869cabd3fbd…
2020-12-22 03:56 UTC2020-12N021825-00270493282021-06-28U-7352020-01-318869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021825-00170493282021-06-28U-7352015-10-08c0c555d07b60…
2020-11-12 02:37 UTC2020-11N021825-00270493282021-06-28U-7352020-01-31c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021825-00170493282021-06-28U-7352015-10-083f01610625f2…
2019-09-15 20:21 UTC2019-09N021825-00170493282021-06-28U-7352015-10-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N021825-00170493282021-06-28U-7352015-10-08ea99ee380514…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 5 · 198 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N021825-001ODE-4172028-04-30caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-001ODE-4202028-04-30caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-001ODE-4212028-04-30caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-002ODE-4172028-04-30caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-002ODE-4202028-04-30caaa826d4ba7…
2026-08-18 06:07:402026-07N021825-002ODE-4212028-04-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021825-001ODE-4172028-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-001ODE-4202028-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-001ODE-4212028-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-002ODE-4172028-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-002ODE-4202028-04-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021825-002ODE-4212028-04-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-001ODE-4172028-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-001ODE-4202028-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-001ODE-4212028-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-002ODE-4172028-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-002ODE-4202028-04-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021825-002ODE-4212028-04-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N021825-001ODE-4172028-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-001ODE-4202028-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-001ODE-4212028-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-002ODE-4172028-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-002ODE-4202028-04-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021825-002ODE-4212028-04-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-001ODE-4172028-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-001ODE-4202028-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-001ODE-4212028-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-002ODE-4172028-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-002ODE-4202028-04-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021825-002ODE-4212028-04-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-001ODE-4172028-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-001ODE-4202028-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-001ODE-4212028-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-002ODE-4172028-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-002ODE-4202028-04-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021825-002ODE-4212028-04-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001I-8592024-04-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001ODE-4172028-04-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001ODE-4202028-04-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021825-001ODE-4212028-04-3003ed91905a0d…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
FERRIPROXDEFERIPRONEChiesi USA, Inc.946718ff-df43-1baa-74d1-e5bcfbe8ad862026-01-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021825
application number: NDA021825
ndc (product): 10122-100
ndc (product): 10122-103

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 14 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
10122-100FERRIPROXdeferiproneChiesi USA, Inc.NDACurrent
10122-100FERRIPROXdeferiproneChiesi USA, Inc.NDACurrent
10122-100FERRIPROXdeferiproneChiesi USA, Inc.NDACurrent
10122-100FERRIPROXdeferiproneChiesi USA, Inc.NDACurrent
10122-103FERRIPROXDEFERIPRONEChiesi USA, Inc.NDACurrent
10122-103FERRIPROXDEFERIPRONEChiesi USA, Inc.NDACurrent
10122-103FERRIPROXDEFERIPRONEChiesi USA, Inc.NDACurrent
10122-103FERRIPROXDEFERIPRONEChiesi USA, Inc.NDACurrent
52609-0006FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent
52609-0006FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent
52609-0006FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent
52609-0007FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent
52609-0007FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent
52609-0007FERRIPROXdeferiproneApoPharma USA, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81761SUPPL 2025-03-28
81759SUPPL 2025-03-27
81758SUPPL 2025-03-27
69444SUPPL2021-12-01
69443SUPPL2021-12-01
69440SUPPL2021-11-30
67390SUPPL2021-05-04
67313SUPPL2021-05-03
67312SUPPL2021-05-03
61935SUPPL2020-02-21
61934SUPPL2020-02-21
61929SUPPL2020-02-21
59502SUPPL2019-07-30
59501SUPPL2019-07-30
59463SUPPL2019-07-26
37728SUPPL2015-03-02
6273SUPPL2015-02-26
37727SUPPL2012-04-24
6272SUPPL2012-04-24
44652ORIG2011-12-02
21835ORIG2011-11-30
37726ORIG2011-10-14
28667ORIG2011-10-14