Application 022393

Type
NDA
Sponsor
CELGENE

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ISTODAXROMIDEPSINPOWDER;INTRAVENOUS10MG/VIALYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022393-001ISTODAXROMIDEPSIN10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N022393-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-0587673890dc5c…
2021-03-12 10:30 UTC2021-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-053f01610625f2…
2019-09-15 20:21 UTC2019-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05b00525d2431f…
2019-07-19 19:46 UTC2019-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSRLD, RS2009-11-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053f0d92c62455…
2023-05-13 08:27 UTC2023-05N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05053a50430f4f…
2023-01-26 05:58 UTC2023-01N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N022393-001ISTODAX10MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2009-11-05cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N022393-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022393-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N022393-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022393-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022393-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022393-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022393-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022393-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022393-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022393-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022393-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022393-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022393-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022393-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022393-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022393-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022393-001AP14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N022393-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N022393-001AP1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N022393-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N022393-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N022393-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N022393-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N022393-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N022393-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N022393-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05N022393-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01N022393-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N022393-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N022393-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N022393-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N022393-001AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N022393-001AP1a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2019-12-13 00:20 UTC2019-12N022393-00176082802021-08-22Drug substance74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N022393-00176117242021-08-22Drug substance74a2ff9319b5…
2021-12-28 21:50 UTC2021-12N022393-00176082802021-08-22Drug substance782e0a99824c…
2021-12-28 21:50 UTC2021-12N022393-00176117242021-08-22Drug substance782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-00176082802021-08-22Drug substance87673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N022393-00176117242021-08-22Drug substance87673890dc5c…
2021-03-12 10:30 UTC2021-03N022393-00176082802021-08-22Drug substance5aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N022393-00176117242021-08-22Drug substance5aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N022393-00176082802021-08-22Drug substance8869cabd3fbd…
2020-12-22 03:56 UTC2020-12N022393-00176117242021-08-22Drug substance8869cabd3fbd…
2020-11-12 02:37 UTC2020-11N022393-00176082802021-08-22Drug substancec0c555d07b60…
2020-11-12 02:37 UTC2020-11N022393-00176117242021-08-22Drug substancec0c555d07b60…
2019-12-14 00:12 UTC2019-12N022393-00176082802021-08-22Drug substance3f01610625f2…
2019-12-14 00:12 UTC2019-12N022393-00176117242021-08-22Drug substance3f01610625f2…
2019-09-15 20:21 UTC2019-09N022393-00176082802021-08-22Drug substanceb00525d2431f…
2019-09-15 20:21 UTC2019-09N022393-00176117242021-08-22Drug substanceb00525d2431f…
2019-07-19 19:46 UTC2019-07N022393-00176082802021-08-22Drug substanceea99ee380514…
2019-07-19 19:46 UTC2019-07N022393-00176117242021-08-22Drug substanceea99ee380514…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ISTODAXROMIDEPSINCelgene Corporation03b39d40-90fe-11df-9de6-0002a5d5c51b2023-01-31Warnings, Adverse reactionsExact identifier
application applno (NDA): 022393
application number: NDA022393
ndc (product): 59572-984

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 10 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0069-0983RomidepsinromidepsinPFIZER LABORATORIES DIV PFIZER INCNDA AUTHORIZED GENERICCurrent
0069-0983RomidepsinromidepsinPFIZER LABORATORIES DIV PFIZER INCNDA AUTHORIZED GENERICCurrent
0703-3125RomidepsinromidepsinTeva Parenteral Medicines, Inc.NDA AUTHORIZED GENERICCurrent
0703-3125RomidepsinromidepsinTeva Parenteral Medicines, Inc.NDA AUTHORIZED GENERICCurrent
0703-3125RomidepsinromidepsinTeva Parenteral Medicines, Inc.NDA AUTHORIZED GENERICCurrent
0703-3125RomidepsinromidepsinTeva Parenteral Medicines, Inc.NDA AUTHORIZED GENERICCurrent
0703-3125RomidepsinromidepsinTeva Parenteral Medicines, Inc.NDA AUTHORIZED GENERICCurrent
59572-984ISTODAXromidepsinCelgene CorporationNDACurrent
59572-984ISTODAXromidepsinCelgene CorporationNDACurrent
59572-984ISTODAXromidepsinCelgene CorporationNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
68273SUPPL2021-08-03
68237SUPPL2021-08-02
67615SUPPL2021-05-27
66867SUPPL2021-03-25
59287SUPPL2019-07-09
56773SUPPL2018-12-18
7318SUPPL2016-08-01
38651SUPPL2016-07-28
29673SUPPL2014-10-21
17308SUPPL2014-10-16
17307SUPPL2013-06-18
7317SUPPL2013-06-14
7316SUPPL2011-10-03
38650SUPPL2011-09-30
29672SUPPL2011-06-27
17306SUPPL2011-06-16
38649SUPPL2011-04-15
29671SUPPL2011-04-15
44745ORIG2010-01-04
42505ORIG2010-01-04
7315ORIG2009-11-13
38648ORIG2009-11-06