Application 022544

Type
NDA
Sponsor
ALMATICA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001GRALISEGABAPENTINTABLET;ORAL300MGYesYes
002GRALISEGABAPENTINTABLET;ORAL600MGYesYes
003GRALISEGABAPENTINTABLET;ORAL450MGYesNo
004GRALISEGABAPENTINTABLET;ORAL750MGYesNo
005GRALISEGABAPENTINTABLET;ORAL900MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N022544-001GRALISEGABAPENTIN300MGTABLET / ORALAB2RLD, RS2011-01-28
N022544-002GRALISEGABAPENTIN600MGTABLET / ORALAB2RLD2011-01-28
N022544-003GRALISEGABAPENTIN450MGTABLET / ORALABRLD2023-04-18
N022544-004GRALISEGABAPENTIN750MGTABLET / ORALABRLD2023-04-18
N022544-005GRALISEGABAPENTIN900MGTABLET / ORALABRLD, RS2023-04-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 5 matching rows.

Application-product, TE code table
Application-productTE code
N022544-001AB2
N022544-002AB2
N022544-003AB
N022544-004AB
N022544-005AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 142 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-003GRALISE450MGTABLET / ORALABRLD2023-04-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-004GRALISE750MGTABLET / ORALABRLD2023-04-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-005GRALISE900MGTABLET / ORALABRLD, RS2023-04-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-003GRALISE450MGTABLET / ORALABRLD2023-04-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-004GRALISE750MGTABLET / ORALABRLD2023-04-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-005GRALISE900MGTABLET / ORALABRLD, RS2023-04-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022544-003GRALISE450MGTABLET / ORALRLD2023-04-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022544-004GRALISE750MGTABLET / ORALRLD2023-04-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-003GRALISE450MGTABLET / ORALRLD2023-04-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-004GRALISE750MGTABLET / ORALRLD2023-04-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-003GRALISE450MGTABLET / ORALRLD2023-04-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-004GRALISE750MGTABLET / ORALRLD2023-04-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-003GRALISE450MGTABLET / ORALRLD2023-04-1803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-004GRALISE750MGTABLET / ORALRLD2023-04-1803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-003GRALISE450MGTABLET / ORALRLD2023-04-182680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-004GRALISE750MGTABLET / ORALRLD2023-04-182680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-001GRALISE300MGTABLET / ORALAB2RLD, RS2011-01-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-002GRALISE600MGTABLET / ORALAB2RLD2011-01-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-003GRALISE450MGTABLET / ORALRLD2023-04-185bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-004GRALISE750MGTABLET / ORALRLD2023-04-185bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-005GRALISE900MGTABLET / ORALRLD, RS2023-04-185bbf6a4d5a75…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 91 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N022544-001AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-002AB21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-004AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N022544-005AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-001AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-002AB2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-004AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N022544-005AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N022544-001AB216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N022544-002AB216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-001AB21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N022544-002AB21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-001AB21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N022544-002AB21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-001AB2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-002AB2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-001AB212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-002AB212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-001AB215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-002AB215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022544-001AB21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022544-002AB21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022544-001AB21d06236e962d9…
2024-10-29 15:01 UTC2024-10N022544-002AB21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022544-001AB2179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022544-002AB2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022544-001AB21301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022544-002AB21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022544-001AB211e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022544-002AB211e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022544-001AB218072bd15b7f6…
2024-05-31 18:47 UTC2024-05N022544-002AB218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-001BX15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-002BX15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022544-001BX15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-002BX15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022544-001BX14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N022544-002BX14b0b4de00fa7…

Observed Orange Book patent history#

Patent history page 1 of 7 · 244 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-00174389272024-02-26U-11142011-03-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N022544-00274389272024-02-26U-111403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-00174389272024-02-26U-11142011-03-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N022544-00274389272024-02-26U-11142680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-00174389272024-02-26U-11142011-03-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N022544-00274389272024-02-26U-11145bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022544-00174389272024-02-26U-11142011-03-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N022544-00274389272024-02-26U-1114d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N022544-00174389272024-02-26U-11142011-03-28d06236e962d9…
2024-10-29 15:01 UTC2024-10N022544-00274389272024-02-26U-1114d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022544-00174389272024-02-26U-11142011-03-2879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N022544-00274389272024-02-26U-111479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022544-00174389272024-02-26U-11142011-03-28301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N022544-00274389272024-02-26U-1114301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022544-00174389272024-02-26U-11142011-03-281e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N022544-00274389272024-02-26U-11141e350fbaab3a…
2024-05-31 18:47 UTC2024-05N022544-00174389272024-02-26U-11142011-03-288072bd15b7f6…
2024-05-31 18:47 UTC2024-05N022544-00274389272024-02-26U-11148072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00177319892022-10-25Drug product2011-03-285c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00181927562022-10-25U-1114Drug product2012-06-085c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00182523322022-10-25U-1114Drug product2012-09-175c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00183339922022-10-25U-1114Drug product2013-01-175c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00174389272024-02-26U-11142011-03-285c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00277319892022-10-25Drug product5c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00281927562022-10-25U-1114Drug product2012-06-085c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00282523322022-10-25U-1114Drug product5c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00283339922022-10-25U-1114Drug product5c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N022544-00274389272024-02-26U-11145c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N022544-00177319892022-10-25Drug product2011-03-285d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00181927562022-10-25U-1114Drug product2012-06-085d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00182523322022-10-25U-1114Drug product2012-09-175d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00183339922022-10-25U-1114Drug product2013-01-175d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00174389272024-02-26U-11142011-03-285d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00277319892022-10-25Drug product5d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00281927562022-10-25U-1114Drug product2012-06-085d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00282523322022-10-25U-1114Drug product5d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00283339922022-10-25U-1114Drug product5d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N022544-00274389272024-02-26U-11145d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N022544-00177319892022-10-25Drug product2011-03-284b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N022544-00181927562022-10-25U-1114Drug product2012-06-084b0b4de00fa7…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
GraliseGABAPENTINAlmatica Pharma LLC466273b1-c9fc-3930-c94b-aa11394d51402025-05-01Warnings, Adverse reactionsExact identifier
application applno (NDA): 022544
application number: NDA022544
ndc (product): 52427-803
ndc (product): 52427-815
ndc (product): 52427-806

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 23 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
13913-004GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-004GralisegabapentinDepomed, Inc.NDACurrent
13913-004GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-004GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-004GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-005GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-005GralisegabapentinDepomed, Inc.NDACurrent
13913-005GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-005GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-005GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-006GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
13913-006GralisegabapentinDepomed, Inc.NDACurrent
13913-006GralisegabapentinAssertio Therapeutics, Inc.NDACurrent
50436-1262GralisegabapentinUnit Dose ServicesNDACurrent
52427-803GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-803GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-803GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-806GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-806GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-806GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-815GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-815GralisegabapentinAlmatica Pharma LLCNDACurrent
52427-815GralisegabapentinAlmatica Pharma LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82106SUPPL 2025-05-01
82058SUPPL 2025-04-29
82057SUPPL 2025-04-29
74054SUPPL 2023-06-13
74060SUPPL 2023-04-26
72415SUPPL2022-10-19
68948SUPPL2021-10-08
68916SUPPL2021-10-08
62531SUPPL2020-04-10
62428SUPPL2020-04-03
17693SUPPL2013-04-01
7518SUPPL2012-08-10
38828SUPPL2012-08-09
29845SUPPL2012-02-03
17692SUPPL2012-02-01
44775ORIG2011-10-18
22051ORIG2011-10-18
7517SUPPL2011-07-05
38827SUPPL2011-06-30
29844SUPPL2011-05-03
23413ORIG2011-03-01
38826ORIG2011-02-04
7516ORIG2011-02-03