Application 040197

Type
ANDA
Sponsor
BARR LABS INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ESTRADIOLESTRADIOLTABLET;ORAL0.5MGNoNo
002ESTRADIOLESTRADIOLTABLET;ORAL1MGNoNo
003ESTRADIOLESTRADIOLTABLET;ORAL2MGNoYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040197-001ESTRADIOLESTRADIOL0.5MGTABLET / ORALAB1997-10-22
A040197-002ESTRADIOLESTRADIOL1MGTABLET / ORALAB1997-10-22
A040197-003ESTRADIOLESTRADIOL2MGTABLET / ORALABRS1997-10-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A040197-001AB
A040197-002AB
A040197-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-225bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-225bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22d06236e962d9…
2024-10-29 15:01 UTC2024-10A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22d06236e962d9…
2024-10-29 15:01 UTC2024-10A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-2279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-2279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-22301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-22301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-221e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-002ESTRADIOL1MGTABLET / ORALAB1997-10-221e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-003ESTRADIOL2MGTABLET / ORALABRS1997-10-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040197-001ESTRADIOL0.5MGTABLET / ORALAB1997-10-228072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A040197-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040197-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A040197-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040197-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040197-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040197-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A040197-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040197-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040197-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040197-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040197-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040197-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040197-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040197-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A040197-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A040197-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040197-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040197-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-002AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040197-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040197-001AB18072bd15b7f6…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 16 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EstradiolESTRADIOLREMEDYREPACK INC.774ee81b-8e29-46af-ab12-7157f63b443b2026-06-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 70518-2369
EstradiolESTRADIOLNorthwind Health Company, LLCf6caf47a-1917-c493-e053-6394a90af63e2026-01-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLNorthwind Health Company, LLCf6cb38ab-fdff-9c07-e053-6294a90ad59a2026-01-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLPD-Rx Pharmaceuticals, Inc.f3a77482-f490-f350-e053-2a95a90ad8cb2025-10-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLNuCare Pharmaceuticals,Inc.c8ac2e13-58d5-4e70-e053-2995a90aff042025-09-22Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 68071-2487
EstradiolESTRADIOLAmerican Health Packaging265a1ee1-f314-4324-a2e1-0120a9a00a202025-05-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLA-S Medication Solutions3e84e3e7-4b50-407f-a215-45363b5413842025-04-15Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLPD-Rx Pharmaceuticals, Inc.d0d1c2c8-b175-4250-9343-d7db65b72e8f2025-03-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLNuCare Pharmaceuticals,Inc.dd7d2d2a-e76b-7dfe-e053-2995a90a790a2025-02-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 68071-2675
EstradiolESTRADIOLPharmPak, Inc.20b50139-4e13-4f0c-aaf5-ecb83911d9e62025-01-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLProficient Rx LP7e570b07-2a9e-49bf-b224-1e34f6eda3ab2024-10-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 63187-741
EstradiolESTRADIOLA-S Medication Solutions7f3c96ce-c855-4372-95ba-7759dd82bcca2024-07-18Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLBryant Ranch Prepack80d6644a-d6f2-48e7-a685-92c4255b19fe2024-04-05Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 71335-0445
ndc (product): 71335-0201
ndc (product): 71335-0430
EstradiolESTRADIOLBryant Ranch Prepack414b846a-d6d9-4e8a-9632-12e296fc13c32024-04-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
ndc (product): 63629-8802
EstradiolESTRADIOLTeva Pharmaceuticals USA, Inc.c4936878-1643-4e7f-9b0d-e4957935aef22024-02-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197
EstradiolESTRADIOLPharmPak, Inc.8f8c5a0b-4d7b-a5cb-e053-2995a90a494e2022-10-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040197
application number: ANDA040197

NDC Listings For This Application#

NDC listings for this application page 2 of 2 · 149 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
63187-741EstradiolEstradiolProficient Rx LPANDACurrent
63187-741EstradiolEstradiolProficient Rx LPANDACurrent
63187-741EstradiolEstradiolProficient Rx LPANDACurrent
63629-6467EstradiolEstradiolBryant Ranch PrepackANDACurrent
63629-6467EstradiolEstradiolBryant Ranch PrepackANDACurrent
63629-6467EstradiolEstradiolBryant Ranch PrepackANDACurrent
63629-8802EstradiolEstradiolBryant Ranch PrepackANDACurrent
63629-8802EstradiolEstradiolBryant Ranch PrepackANDACurrent
66267-092EstradiolEstradiolNuCare Pharmaceuticals, IncANDACurrent
66267-092EstradiolEstradiolNuCare Pharmaceuticals, IncANDACurrent
66267-093EstradiolEstradiolNuCare Pharmaceuticals, Inc.ANDACurrent
66267-093EstradiolEstradiolNuCare Pharmaceuticals, Inc.ANDACurrent
68071-2429EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68071-2429EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68071-2487EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68071-2675EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68071-2694EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68071-3170EstradiolEstradiolNuCare Pharmaceuticals, Inc.ANDACurrent
68071-3202EstradiolEstradiolNuCare Pharmaceuticals, Inc.ANDACurrent
68071-4195EstradiolEstradiolNuCare Pharmaceuticals,Inc.ANDACurrent
68788-7054EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-7892EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-7892EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-7961EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-7961EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-8063EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-8063EstradiolEstradiolPreferred Pharmaceuticals Inc.ANDACurrent
68788-9901EstradiolEstradiolPreferred Pharmaceuticals, Inc.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0834EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0920EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0920EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0920EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0920EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-0920EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2368EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2368EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2369EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2369EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2369EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2595EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2595EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70518-2595EstradiolEstradiolREMEDYREPACK INC.ANDACurrent
70934-215EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-215EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-393EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-393EstradiolEstradiolDenton Pharma, Inc. dba Northwind PharmaceuticalsANDACurrent
70934-506EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-506EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-541EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
70934-786EstradiolEstradiolDenton Pharma, Inc. dba Northwind PharmaceuticalsANDACurrent
70934-927EstradiolEstradiolDenton Pharma, Inc. DBA Northwind PharmaceuticalsANDACurrent
71335-0201EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0201EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0430EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0430EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0430EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0445EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-0445EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-1488EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-1719EstradiolEstradiolBryant Ranch PrepackANDACurrent
71335-1973EstradiolEstradiolBryant Ranch PrepackANDACurrent
72189-183EstradiolEstradiolDirect RxANDACurrent
72189-183EstradiolEstradiolDirect RxANDACurrent
72189-198ESTRADIOLESTRADIOLDirect RxANDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
42593ORIG2011-03-10