Application 090081
- Type
- ANDA
- Sponsor
- MAYNE PHARMA
Application Products#
| Product | Drug | Ingredient | Form | Strength | Reference drug | Reference standard |
|---|---|---|---|---|---|---|
| 001 | DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE; ETHINYL ESTRADIOL | TABLET;ORAL-28 | 3MG;0.03MG | No | No |
Orange Book products#
| Application-product | Trade name | Ingredient | Strength | Dosage form / route | TE codes | RLD / RS | Approval date |
|---|---|---|---|---|---|---|---|
| A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE; ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 |
Therapeutic equivalence codes#
| Application-product | TE code |
|---|---|
| A090081-001 | AB |
Observed Orange Book product history#
Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
| Captured | Edition | Application-product | Trade name | Strength | Dosage form / route | Product TE source text | RLD / RS | Approval date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|
| 2026-02-19 14:30 UTC | 2026-02 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 011fe1cb6892… | |
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 31067a03dcf5… | |
| 2025-08-23 18:47 UTC | 2025-08 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 6a471c1ec25d… | |
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | fd3edfee7708… | |
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | b8a1b40f171c… | |
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 03ed91905a0d… | |
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 2680178bc6a6… | |
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 5bbf6a4d5a75… | |
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | d8e5a09893c0… | |
| 2024-10-29 15:01 UTC | 2024-10 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | d06236e962d9… | |
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 79d66fd596c7… | |
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 301d65b070ca… | |
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 1e350fbaab3a… | |
| 2024-05-31 18:47 UTC | 2024-05 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 8072bd15b7f6… | |
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 5c6f7cd8ea54… | |
| 2022-04-08 23:34 UTC | 2022-04 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 5d02ea3f76ae… | |
| 2022-04-04 05:41 UTC | 2022-04 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 4b0b4de00fa7… | |
| 2019-12-13 00:20 UTC | 2019-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 74a2ff9319b5… | |
| 2022-03-09 01:35 UTC | 2022-03 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | bb7c543d1eb4… | |
| 2021-12-28 21:50 UTC | 2021-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 782e0a99824c… | |
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 87673890dc5c… | |
| 2021-03-12 10:30 UTC | 2021-03 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 5aa47cf7b7d7… | |
| 2020-12-22 03:56 UTC | 2020-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 8869cabd3fbd… | |
| 2020-11-12 02:37 UTC | 2020-11 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | c0c555d07b60… | |
| 2019-12-14 00:12 UTC | 2019-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 3f01610625f2… | |
| 2019-09-15 20:21 UTC | 2019-09 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | b00525d2431f… | |
| 2019-07-19 19:46 UTC | 2019-07 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | ea99ee380514… | |
| 2024-03-16 18:09 UTC · 4 captures of this ZIP | 2024-03 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 6a51e52b5d6a… | |
| 2024-02-18 07:12 UTC | 2024-02 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 1c564ffb4f44… | |
| 2023-12-20 04:57 UTC | 2023-12 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | ea1830bbd6c7… | |
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | a72a2bbeb626… | |
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 9b2671bbb829… | |
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | a67488948f0b… | |
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 3f0d92c62455… | |
| 2023-05-13 08:27 UTC | 2023-05 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 053a50430f4f… | |
| 2023-01-26 05:58 UTC | 2023-01 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 3bdfa0b2c4d7… | |
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | 3a93d1ddd44b… | |
| 2022-10-28 04:53 UTC | 2022-10 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | f41ea6bd6efb… | |
| 2022-09-29 23:25 UTC | 2022-09 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | e64feba35796… | |
| 2022-07-09 03:26 UTC · 3 captures of this ZIP | 2022-07 | A090081-001 | DROSPIRENONE AND ETHINYL ESTRADIOL | 3MG;0.03MG | TABLET / ORAL-28 | AB | 2010-09-07 | cb3db0bc1861… |
Observed Orange Book normalized TE history#
| Captured | Edition | Application-product | TE code | Order | Source SHA-256 |
|---|---|---|---|---|---|
| 2026-02-19 14:30 UTC | 2026-02 | A090081-001 | AB | 1 | 011fe1cb6892… |
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | A090081-001 | AB | 1 | 31067a03dcf5… |
| 2025-08-23 18:47 UTC | 2025-08 | A090081-001 | AB | 1 | 6a471c1ec25d… |
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | A090081-001 | AB | 1 | fd3edfee7708… |
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | A090081-001 | AB | 1 | b8a1b40f171c… |
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | A090081-001 | AB | 1 | 03ed91905a0d… |
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | A090081-001 | AB | 1 | 2680178bc6a6… |
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | A090081-001 | AB | 1 | 5bbf6a4d5a75… |
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | A090081-001 | AB | 1 | d8e5a09893c0… |
| 2024-10-29 15:01 UTC | 2024-10 | A090081-001 | AB | 1 | d06236e962d9… |
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | A090081-001 | AB | 1 | 79d66fd596c7… |
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | A090081-001 | AB | 1 | 301d65b070ca… |
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | A090081-001 | AB | 1 | 1e350fbaab3a… |
| 2024-05-31 18:47 UTC | 2024-05 | A090081-001 | AB | 1 | 8072bd15b7f6… |
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | A090081-001 | AB | 1 | 5c6f7cd8ea54… |
| 2022-04-08 23:34 UTC | 2022-04 | A090081-001 | AB | 1 | 5d02ea3f76ae… |
| 2022-04-04 05:41 UTC | 2022-04 | A090081-001 | AB | 1 | 4b0b4de00fa7… |
| 2019-12-13 00:20 UTC | 2019-12 | A090081-001 | AB | 1 | 74a2ff9319b5… |
| 2022-03-09 01:35 UTC | 2022-03 | A090081-001 | AB | 1 | bb7c543d1eb4… |
| 2021-12-28 21:50 UTC | 2021-12 | A090081-001 | AB | 1 | 782e0a99824c… |
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | A090081-001 | AB | 1 | 87673890dc5c… |
| 2021-03-12 10:30 UTC | 2021-03 | A090081-001 | AB | 1 | 5aa47cf7b7d7… |
| 2020-12-22 03:56 UTC | 2020-12 | A090081-001 | AB | 1 | 8869cabd3fbd… |
| 2020-11-12 02:37 UTC | 2020-11 | A090081-001 | AB | 1 | c0c555d07b60… |
| 2019-12-14 00:12 UTC | 2019-12 | A090081-001 | AB | 1 | 3f01610625f2… |
| 2019-09-15 20:21 UTC | 2019-09 | A090081-001 | AB | 1 | b00525d2431f… |
| 2019-07-19 19:46 UTC | 2019-07 | A090081-001 | AB | 1 | ea99ee380514… |
| 2024-03-16 18:09 UTC · 4 captures of this ZIP | 2024-03 | A090081-001 | AB | 1 | 6a51e52b5d6a… |
| 2024-02-18 07:12 UTC | 2024-02 | A090081-001 | AB | 1 | 1c564ffb4f44… |
| 2023-12-20 04:57 UTC | 2023-12 | A090081-001 | AB | 1 | ea1830bbd6c7… |
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | A090081-001 | AB | 1 | a72a2bbeb626… |
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | A090081-001 | AB | 1 | 9b2671bbb829… |
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | A090081-001 | AB | 1 | a67488948f0b… |
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | A090081-001 | AB | 1 | 3f0d92c62455… |
| 2023-05-13 08:27 UTC | 2023-05 | A090081-001 | AB | 1 | 053a50430f4f… |
| 2023-01-26 05:58 UTC | 2023-01 | A090081-001 | AB | 1 | 3bdfa0b2c4d7… |
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | A090081-001 | AB | 1 | 3a93d1ddd44b… |
| 2022-10-28 04:53 UTC | 2022-10 | A090081-001 | AB | 1 | f41ea6bd6efb… |
| 2022-09-29 23:25 UTC | 2022-09 | A090081-001 | AB | 1 | e64feba35796… |
| 2022-07-09 03:26 UTC · 3 captures of this ZIP | 2022-07 | A090081-001 | AB | 1 | cb3db0bc1861… |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE AND ETHINYL ESTRADIOL | Redpharm Drug | 57d1d945-9fc9-4e79-e063-6294a90a738a | 2026-07-30 | Boxed warning, Warnings, Adverse reactions | DROSPIRENONE AND ETHINYL ESTRADIOL |
| DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE AND ETHINYL ESTRADIOL | Apotex Corp. | 9187a357-e95d-4733-9627-f19522b86373 | 2026-05-14 | Boxed warning, Warnings, Adverse reactions | DROSPIRENONE AND ETHINYL ESTRADIOL |
| drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | A-S Medication Solutions | 6edead7f-a41f-4d0b-a27a-b2047ed4eea0 | 2026-03-03 | Boxed warning, Warnings, Adverse reactions | drospirenone and ethinyl estradiol |
| drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | Glenmark Pharmaceuticals Inc., USA | 0f8f8a21-cee8-462f-98b3-6c06f2f33e0d | 2026-01-29 | Boxed warning, Warnings, Adverse reactions | drospirenone and ethinyl estradiol |
| drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | Glenmark Pharmaceuticals Inc., USA | 6d85f252-307c-4aa8-9572-1e74c9819283 | 2025-12-12 | Boxed warning, Warnings, Adverse reactions | drospirenone and ethinyl estradiol |
| DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE AND ETHINYL ESTRADIOL | Lupin Pharmaceuticals, Inc. | a8955f3b-afc9-4ef0-8946-9c97ab5b2e05 | 2025-12-02 | Boxed warning, Warnings, Adverse reactions | DROSPIRENONE AND ETHINYL ESTRADIOL |
| Drospirenone and Ethinyl Estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | NorthStar Rx LLC | c88c3eb8-3bf5-4004-a7ab-7218cd2f9182 | 2025-08-07 | Boxed warning, Warnings, Adverse reactions | Drospirenone and Ethinyl Estradiol |
| drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | A-S Medication Solutions | 9b1f944b-b05b-4ab0-bcf6-42f426b07c45 | 2024-05-07 | Boxed warning, Warnings, Adverse reactions | drospirenone and ethinyl estradiol |
| DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE AND ETHINYL ESTRADIOL | Naari Pte. Limited | d96f0dd8-4eb9-42f7-ab5e-b5515dcf73d6 | 2024-04-22 | Boxed warning, Warnings, Adverse reactions | DROSPIRENONE AND ETHINYL ESTRADIOL |
| Drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | Camber Pharmaceuticals, Inc. | 71f90c73-63c2-432b-b112-cbdbd26b965c | 2023-11-28 | Boxed warning, Warnings, Adverse reactions | Drospirenone and ethinyl estradiol |
| DROSPIRENONE AND ETHINYL ESTRADIOL | DROSPIRENONE AND ETHINYL ESTRADIOL | Mylan Pharmaceuticals Inc. | 25f9b952-cc1d-454e-a3ec-834ba1774b6b | 2023-09-22 | Boxed warning, Warnings, Adverse reactions | DROSPIRENONE AND ETHINYL ESTRADIOL |
| Drospirenone and Ethinyl Estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | Camber Pharmaceuticals, Inc. | a1f6ea0e-7c14-47c4-83a2-3797bd012eb4 | 2023-09-19 | Boxed warning, Warnings, Adverse reactions | Drospirenone and Ethinyl Estradiol |
| drospirenone and ethinyl estradiol | DROSPIRENONE AND ETHINYL ESTRADIOL | Proficient Rx LP | 151048e4-849c-4a66-bf18-c0351e8eefeb | 2022-07-01 | Boxed warning, Warnings, Adverse reactions | drospirenone and ethinyl estradiol |
NDC Listings For This Application#
| NDC | Name | Nonproprietary name | Labeler | Marketing category | Status |
|---|---|---|---|---|---|
| 51862-036 | Zarah | Drospirenone and Ethinyl Estradiol | Mayne Pharma Inc. | ANDA | Current |
| 51862-036 | Zarah | Drospirenone and Ethinyl Estradiol | Mayne Pharma Inc. | ANDA | Current |
| 52544-981 | Zarah | Drospirenone and Ethinyl Estradiol | Actavis Pharma, Inc. | ANDA | Current |
| 53002-1627 | Zarah | Drospirenone and Ethinyl Estradiol | RPK Pharmaceuticals, Inc. | ANDA | Current |
| 53002-1627 | Zarah | Drospirenone and Ethinyl Estradiol | RPK Pharmaceuticals, Inc. | ANDA | Current |
Documents#
| Document | Submission type | Date |
|---|---|---|
| 31449 | ORIG | 2010-03-22 |