Application 202343

Type
NDA
Sponsor
MERCK SHARP DOHME

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
002JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
003JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
004JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
005JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
006JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATETABLET;ORAL40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N202343-001JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07
N202343-002JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07
N202343-003JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07
N202343-004JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18
N202343-005JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18
N202343-006JUVISYNCSIMVASTATIN; SITAGLIPTIN PHOSPHATE40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18

Orange Book patents#

Current patent rows page 1 of 1 · 12 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N202343-00173267082026-04-11U-1188Drug substance, Drug product2011-11-04
N202343-0017326708*PED2026-10-11Pediatric extension
N202343-00273267082026-04-11U-1188Drug substance, Drug product
N202343-0027326708*PED2026-10-11Pediatric extension
N202343-00373267082026-04-11U-1188Drug substance, Drug product
N202343-0037326708*PED2026-10-11Pediatric extension
N202343-00473267082026-04-11U-1188Drug substance, Drug product
N202343-0047326708*PED2026-10-11Pediatric extension
N202343-00573267082026-04-11U-1188Drug substance, Drug product
N202343-0057326708*PED2026-10-11Pediatric extension
N202343-00673267082026-04-11U-1188Drug substance, Drug product
N202343-0067326708*PED2026-10-11Pediatric extension

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 252 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-005JUVISYNC20MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202343-006JUVISYNC40MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202343-001JUVISYNC10MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202343-002JUVISYNC20MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202343-003JUVISYNC40MG;EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2011-10-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202343-004JUVISYNC10MG;EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**TABLET / ORALRLD2012-09-1803ed91905a0d…

Observed Orange Book patent history#

Patent history page 1 of 37 · 1,470 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N202343-00173267082026-04-11U-1188Drug substance, Drug product2011-11-04caaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0017326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-00273267082026-04-11U-1188Drug substance, Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0027326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-00373267082026-04-11U-1188Drug substance, Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0037326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-00473267082026-04-11U-1188Drug substance, Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0047326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-00573267082026-04-11U-1188Drug substance, Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0057326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-00673267082026-04-11U-1188Drug substance, Drug productcaaa826d4ba7…
2026-08-18 06:07:402026-07N202343-0067326708*PED2026-10-11Pediatric extensioncaaa826d4ba7…
2026-02-19 14:30 UTC2026-02N202343-00173267082026-04-11U-1188Drug substance, Drug product2011-11-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0017326708*PED2026-10-11Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-00273267082026-04-11U-1188Drug substance, Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0027326708*PED2026-10-11Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-00373267082026-04-11U-1188Drug substance, Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0037326708*PED2026-10-11Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-00473267082026-04-11U-1188Drug substance, Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0047326708*PED2026-10-11Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-00573267082026-04-11U-1188Drug substance, Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0057326708*PED2026-10-11Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-00673267082026-04-11U-1188Drug substance, Drug product011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202343-0067326708*PED2026-10-11Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00173267082026-04-11U-1188Drug substance, Drug product2011-11-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0017326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00273267082026-04-11U-1188Drug substance, Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0027326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00373267082026-04-11U-1188Drug substance, Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0037326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00473267082026-04-11U-1188Drug substance, Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0047326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00573267082026-04-11U-1188Drug substance, Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0057326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-00673267082026-04-11U-1188Drug substance, Drug product31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202343-0067326708*PED2026-10-11Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N202343-00173267082026-04-11U-1188Drug substance, Drug product2011-11-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-0017326708*PED2026-10-11Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-00273267082026-04-11U-1188Drug substance, Drug product6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202343-0027326708*PED2026-10-11Pediatric extension6a471c1ec25d…

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
32243SUPPL2014-02-26
19330SUPPL2014-02-25
19328SUPPL2013-10-31
32241SUPPL2013-10-28
32242SUPPL2013-08-22
19329SUPPL2013-08-19
10033SUPPL2013-02-13
40172SUPPL2013-02-11
40171SUPPL2012-11-06
32240SUPPL2012-11-06
32239SUPPL2012-11-06
19327SUPPL2012-11-06
32238SUPPL2012-09-24
10032SUPPL2012-09-24
10031SUPPL2012-09-24
40170SUPPL2012-09-20
19326SUPPL2012-09-20
19325SUPPL2012-09-20
44853ORIG2012-07-13
43397ORIG2012-07-13
40169ORIG2011-10-07
23492ORIG2011-10-07
10030ORIG2011-10-07