Application 202379

Type: NDA
Sponsor: JANSSEN BIOTECH

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	ZYTIGA	ABIRATERONE ACETATE	TABLET;ORAL	250MG	Yes	No
002	ZYTIGA	ABIRATERONE ACETATE	TABLET;ORAL	500MG	Yes	Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N202379-001	ZYTIGA	ABIRATERONE ACETATE	250MG	TABLET / ORAL	AB	RLD	2011-04-28
N202379-002	ZYTIGA	ABIRATERONE ACETATE	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
N202379-001	AB
N202379-002	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N202379-002	ZYTIGA	500MG	TABLET / ORAL		RLD, RS	2017-04-14	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N202379-001	ZYTIGA	250MG	TABLET / ORAL	AB	RLD	2011-04-28	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N202379-002	ZYTIGA	500MG	TABLET / ORAL	AB	RLD, RS	2017-04-14	`782e0a99824c…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 76 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N202379-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N202379-002	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N202379-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N202379-002	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N202379-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N202379-002	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N202379-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N202379-002	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N202379-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N202379-002	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N202379-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N202379-002	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N202379-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N202379-002	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N202379-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N202379-002	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N202379-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N202379-002	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N202379-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N202379-002	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N202379-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N202379-002	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N202379-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N202379-002	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N202379-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N202379-002	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N202379-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N202379-002	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N202379-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N202379-002	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N202379-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N202379-002	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N202379-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N202379-002	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N202379-001	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N202379-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	N202379-002	AB	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N202379-001	AB	1	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N202379-002	AB	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N202379-001	AB	1	`87673890dc5c…`

Observed Orange Book patent history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N202379-002	8822438	2027-08-24	U-2235	Delist requested	2017-08-02	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N202379-002	8822438	2027-08-24	U-1580	Delist requested	2017-08-02	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N202379-002	8822438	2027-08-24	U-1579	Delist requested	2017-08-02	`74a2ff9319b5…`
2020-12-22 03:56 UTC	2020-12	N202379-002	8822438	2027-08-24	U-2235	Delist requested	2017-08-02	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N202379-002	8822438	2027-08-24	U-1580	Delist requested	2017-08-02	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N202379-002	8822438	2027-08-24	U-1579	Delist requested	2017-08-02	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N202379-002	8822438	2027-08-24	U-2235	Delist requested	2017-08-02	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N202379-002	8822438	2027-08-24	U-1580	Delist requested	2017-08-02	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N202379-002	8822438	2027-08-24	U-1579	Delist requested	2017-08-02	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N202379-002	8822438	2027-08-24	U-2235	Delist requested	2017-08-02	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N202379-002	8822438	2027-08-24	U-1580	Delist requested	2017-08-02	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N202379-002	8822438	2027-08-24	U-1579	Delist requested	2017-08-02	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N202379-001	8822438	2027-08-24	U-1580		2014-10-01	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-001	8822438	2027-08-24	U-2235		2014-10-01	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-001	8822438	2027-08-24	U-1579		2014-10-01	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-002	8822438	2027-08-24	U-2235		2017-08-02	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-002	8822438	2027-08-24	U-1580		2017-08-02	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-002	8822438	2027-08-24	U-1579		2017-08-02	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N202379-001	8822438	2027-08-24	U-1579		2014-10-01	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-001	8822438	2027-08-24	U-1580		2014-10-01	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-001	8822438	2027-08-24	U-2235		2014-10-01	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-002	8822438	2027-08-24	U-2235		2017-08-02	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-002	8822438	2027-08-24	U-1580		2017-08-02	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-002	8822438	2027-08-24	U-1579		2017-08-02	`ea99ee380514…`

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	Exclusivity code	Expiration	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N202379-001	I-765	2021-02-07	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N202379-002	I-765	2021-02-07	`74a2ff9319b5…`
2021-12-28 21:50 UTC	2021-12	N202379-001	I-765	2021-02-07	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N202379-002	I-765	2021-02-07	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N202379-001	I-765	2021-02-07	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N202379-002	I-765	2021-02-07	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N202379-001	I-765	2021-02-07	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	N202379-002	I-765	2021-02-07	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N202379-001	I-765	2021-02-07	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N202379-002	I-765	2021-02-07	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N202379-001	I-765	2021-02-07	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N202379-002	I-765	2021-02-07	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N202379-001	I-765	2021-02-07	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N202379-002	I-765	2021-02-07	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N202379-001	I-765	2021-02-07	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N202379-002	I-765	2021-02-07	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N202379-001	I-765	2021-02-07	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N202379-002	I-765	2021-02-07	`ea99ee380514…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Zytiga	ABIRATERONE ACETATE	Janssen Biotech, Inc.	4e338e89-3cf2-48eb-b6e2-a06c608c6513	2025-03-28	Warnings, Adverse reactions	Exact identifier application applno (NDA): 202379 application number: NDA202379 ndc (product): 57894-195 ndc (product): 57894-150

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 23 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-150	Zytiga	abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-155	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA AUTHORIZED GENERIC	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-195	Zytiga	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-199	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-199	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current
57894-199	Abiraterone acetate	Abiraterone acetate	Janssen Biotech, Inc.	NDA	Current

Documents#

Document, Submission type, Date table
Document	Submission type	Date
68458	SUPPL	2021-08-25
68455	SUPPL	2021-08-25
64851	SUPPL	2020-10-06
64850	SUPPL	2020-10-06
64826	SUPPL	2020-10-05
64825	SUPPL	2020-10-05
58979	SUPPL	2019-06-05
58978	SUPPL	2019-06-05
58973	SUPPL	2019-06-05
58972	SUPPL	2019-06-05
55746	SUPPL	2018-10-01
55617	SUPPL	2018-09-26
54304	SUPPL	2018-05-22
52563	SUPPL	2018-02-12
52522	SUPPL	2018-02-08
45794	SUPPL	2016-11-02
40178	SUPPL	2016-05-20
32253	SUPPL	2016-05-19
19342	SUPPL	2015-12-15
32252	SUPPL	2015-12-11
19341	SUPPL	2015-05-27
10041	SUPPL	2015-05-22
32251	SUPPL	2015-03-24
19340	SUPPL	2015-03-24
40177	SUPPL	2015-01-29
10040	SUPPL	2015-01-26
10039	SUPPL	2014-05-19
19339	SUPPL	2014-05-15
22888	SUPPL	2014-01-16
19338	SUPPL	2013-09-17
10038	SUPPL	2013-09-13
19337	SUPPL	2012-12-14
10037	SUPPL	2012-12-12
32250	SUPPL	2012-09-20
40176	SUPPL	2012-09-17
40175	SUPPL	2012-07-13
10036	SUPPL	2012-07-09
44856	ORIG	2011-05-27
43400	ORIG	2011-05-27
32249	ORIG	2011-05-03
19336	ORIG	2011-04-28