Application 203094

Type
NDA
Sponsor
GILEAD SCIENCES INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001TYBOSTCOBICISTATTABLET;ORAL150MGYesYes
002TYBOSTCOBICISTATTABLET;ORAL90MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N203094-001TYBOSTCOBICISTAT150MGTABLET / ORALRLD2014-09-24
N203094-002TYBOSTCOBICISTAT90MGTABLET / ORALRLD2025-06-20

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-16
N203094-0018148374*PED2030-03-03Pediatric extension
N203094-001100397182032-10-06Drug product2018-09-04
N203094-00110039718*PED2033-04-06Pediatric extension
N203094-00281483742029-09-03U-1279Drug substance, Drug product2025-07-15
N203094-0028148374*PED2030-03-03Pediatric extension
N203094-002100397182032-10-06Drug product2025-07-15
N203094-00210039718*PED2033-04-06Pediatric extension

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 1 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N203094-001ODE-2602026-08-22

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 45 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-002TYBOST90MGTABLET / ORALRLD2025-06-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-002TYBOST90MGTABLET / ORALRLD2025-06-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-002TYBOST90MGTABLET / ORALRLD2025-06-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-2487673890dc5c…
2021-03-12 10:30 UTC2021-03N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-245aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-248869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-243f01610625f2…
2019-09-15 20:21 UTC2019-09N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24b00525d2431f…
2019-07-19 19:46 UTC2019-07N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203094-001TYBOST150MGTABLET / ORALABRLD, RS2014-09-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-243f0d92c62455…
2023-05-13 08:27 UTC2023-05N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-24053a50430f4f…
2023-01-26 05:58 UTC2023-01N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-243bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N203094-001TYBOST150MGTABLET / ORALRLD, RS2014-09-243a93d1ddd44b…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203094-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203094-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203094-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203094-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203094-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203094-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203094-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203094-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203094-001AB11c564ffb4f44…

Observed Orange Book patent history#

Patent history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-0018148374*PED2030-03-03Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-001100397182032-10-06Drug product2018-09-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-00110039718*PED2033-04-06Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-00281483742029-09-03U-1279Drug substance, Drug product2025-07-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-0028148374*PED2030-03-03Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-002100397182032-10-06Drug product2025-07-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203094-00210039718*PED2033-04-06Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-0018148374*PED2030-03-03Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-001100397182032-10-06Drug product2018-09-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-00110039718*PED2033-04-06Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-00281483742029-09-03U-1279Drug substance, Drug product2025-07-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-0028148374*PED2030-03-03Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-002100397182032-10-06Drug product2025-07-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-00210039718*PED2033-04-06Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-0018148374*PED2030-03-03Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-001100397182032-10-06Drug product2018-09-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-00110039718*PED2033-04-06Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-00281483742029-09-03U-1279Drug substance, Drug product2025-07-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-0028148374*PED2030-03-03Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-002100397182032-10-06Drug product2025-07-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203094-00210039718*PED2033-04-06Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-0018148374*PED2030-03-03Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-001100397182032-10-06Drug product2018-09-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-00110039718*PED2033-04-06Pediatric extensionfd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-0018148374*PED2030-03-03Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-001100397182032-10-06Drug product2018-09-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-00110039718*PED2033-04-06Pediatric extensionb8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-0018148374*PED2030-03-03Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-001100397182032-10-06Drug product2018-09-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-00110039718*PED2033-04-06Pediatric extension03ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-00181483742029-09-03U-1279Drug substance, Drug product2014-10-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-0018148374*PED2030-03-03Pediatric extension2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-001100397182032-10-06Drug product2018-09-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-00110039718*PED2033-04-06Pediatric extension2680178bc6a6…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 55 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N203094-001ODE-2602026-08-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203094-001ODE-2602026-08-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N203094-001ODE-2602026-08-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203094-001ODE-2602026-08-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203094-001ODE-2602026-08-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203094-001ODE-2602026-08-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203094-001ODE-2602026-08-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203094-001ODE-2602026-08-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203094-001ODE-2602026-08-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203094-001ODE-2602026-08-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203094-001ODE-2602026-08-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203094-001ODE-2602026-08-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203094-001ODE-2602026-08-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203094-001ODE-2602026-08-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203094-001NPP2022-08-225c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203094-001ODE-2602026-08-225c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203094-001NPP2022-08-225d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N203094-001ODE-2602026-08-225d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203094-001NPP2022-08-224b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N203094-001ODE-2602026-08-224b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203094-001NPP2022-08-2274a2ff9319b5…
2019-12-13 00:20 UTC2019-12N203094-001ODE-2602026-08-2274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203094-001NPP2022-08-22bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N203094-001ODE-2602026-08-22bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203094-001NPP2022-08-22782e0a99824c…
2021-12-28 21:50 UTC2021-12N203094-001ODE-2602026-08-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203094-001NPP2022-08-2287673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203094-001ODE-2602026-08-2287673890dc5c…
2021-03-12 10:30 UTC2021-03N203094-001NPP2022-08-225aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N203094-001ODE-2602026-08-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203094-001NPP2022-08-228869cabd3fbd…
2020-12-22 03:56 UTC2020-12N203094-001ODE-2602026-08-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203094-001NPP2022-08-22c0c555d07b60…
2020-11-12 02:37 UTC2020-11N203094-001ODE-2602026-08-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203094-001NPP2022-08-223f01610625f2…
2019-12-14 00:12 UTC2019-12N203094-001ODE-2602026-08-223f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203094-001ODE-2602026-08-226a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203094-001ODE-2602026-08-221c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203094-001ODE-2602026-08-22ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203094-001ODE-2602026-08-22a72a2bbeb626…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TybostCOBICISTATGilead Sciences, Inc.3784c35c-e87f-410c-900b-8fd6313c60102026-02-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 203094
application number: NDA203094
ndc (product): 61958-1401

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 7 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent
61958-1401TybostCOBICISTATGilead Sciences, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82636SUPPL 2026-05-04
82635SUPPL 2026-05-04
82641SUPPL 2025-06-24
82640SUPPL 2025-06-24
68586SUPPL2021-09-13
68568SUPPL2021-09-10
64480SUPPL2020-09-02
64396SUPPL2020-08-24
60245SUPPL2019-10-07
60219SUPPL2019-10-04
59828SUPPL2019-08-26
59825SUPPL2019-08-23
56216SUPPL2018-10-31
56210SUPPL2018-10-31
55150SUPPL2018-08-10
55057SUPPL2018-07-30
49632SUPPL2017-08-30
49586SUPPL2017-08-30
48295SUPPL2017-05-09
48247SUPPL2017-05-05
40259SUPPL2016-06-21
10157SUPPL2016-06-21
40258SUPPL2015-12-01
32370SUPPL2015-11-27
24426ORIG2015-05-28
22908ORIG2015-05-28
19419ORIG2014-10-03
10156ORIG2014-09-29
32369ORIG2014-09-26
62920SUPPL1900-01-01
62919SUPPL1900-01-01