Application 205786

Type
NDA
Sponsor
MERCK SHARP DOHME

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ISENTRESSRALTEGRAVIR POTASSIUMPOWDER;ORALEQ 100MG BASE/PACKETYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205786-001ISENTRESSRALTEGRAVIR POTASSIUMEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16
N205786-0017754731*PED2029-09-11Pediatric extension

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-208072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-205c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-205d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-204b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-2074a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-2087673890dc5c…
2021-03-12 10:30 UTC2021-03N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-205aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-208869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-203f01610625f2…
2019-09-15 20:21 UTC2019-09N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20b00525d2431f…
2019-07-19 19:46 UTC2019-07N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-206a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-201c564ffb4f44…
2023-12-20 04:57 UTC2023-12N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-209b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-203f0d92c62455…
2023-05-13 08:27 UTC2023-05N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20053a50430f4f…
2023-01-26 05:58 UTC2023-01N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-203bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-203a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N205786-001ISENTRESSEQ 100MG BASE/PACKETPOWDER / ORALRLD, RS2013-12-20e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 6 · 227 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16caaa826d4ba7…
2026-08-18 06:07:402026-07N205786-0017754731*PED2029-09-11Pediatric extensioncaaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205786-0017754731*PED2029-09-11Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205786-0017754731*PED2029-09-11Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205786-0017754731*PED2029-09-11Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205786-0017754731*PED2029-09-11Pediatric extensionfd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205786-0017754731*PED2029-09-11Pediatric extensionb8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205786-0017169780*PED2024-04-03Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205786-0017754731*PED2029-09-11Pediatric extension03ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205786-0017169780*PED2024-04-03Pediatric extension2680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205786-0017754731*PED2029-09-11Pediatric extension2680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205786-0017169780*PED2024-04-03Pediatric extension5bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205786-0017754731*PED2029-09-11Pediatric extension5bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205786-0017169780*PED2024-04-03Pediatric extensiond8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205786-0017754731*PED2029-09-11Pediatric extensiond8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205786-0017169780*PED2024-04-03Pediatric extensiond06236e962d9…
2024-10-29 15:01 UTC2024-10N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N205786-0017754731*PED2029-09-11Pediatric extensiond06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205786-0017169780*PED2024-04-03Pediatric extension79d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-1679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205786-0017754731*PED2029-09-11Pediatric extension79d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205786-0017169780*PED2024-04-03Pediatric extension301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-16301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205786-0017754731*PED2029-09-11Pediatric extension301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205786-0017169780*PED2024-04-03Pediatric extension1e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-161e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205786-0017754731*PED2029-09-11Pediatric extension1e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205786-0017169780*PED2024-04-03Pediatric extension8072bd15b7f6…
2024-05-31 18:47 UTC2024-05N205786-00177547312029-03-11U-257Drug substance, Drug product2014-01-168072bd15b7f6…
2024-05-31 18:47 UTC2024-05N205786-0017754731*PED2029-09-11Pediatric extension8072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205786-00172177132022-10-21U-2572014-01-165c6f7cd8ea54…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N205786-001NPP2020-11-2274a2ff9319b5…
2019-12-13 00:20 UTC2019-12N205786-001PED2021-05-2274a2ff9319b5…
2021-12-28 21:50 UTC2021-12N205786-001PED2021-05-22782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205786-001PED2021-05-2287673890dc5c…
2021-03-12 10:30 UTC2021-03N205786-001PED2021-05-225aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205786-001NPP2020-11-228869cabd3fbd…
2020-12-22 03:56 UTC2020-12N205786-001PED2021-05-228869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205786-001NPP2020-11-22c0c555d07b60…
2020-11-12 02:37 UTC2020-11N205786-001PED2021-05-22c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205786-001NPP2020-11-223f01610625f2…
2019-12-14 00:12 UTC2019-12N205786-001PED2021-05-223f01610625f2…
2019-09-15 20:21 UTC2019-09N205786-001NPP2020-11-22b00525d2431f…
2019-09-15 20:21 UTC2019-09N205786-001PED2021-05-22b00525d2431f…
2019-07-19 19:46 UTC2019-07N205786-001NPP2020-11-22ea99ee380514…
2019-07-19 19:46 UTC2019-07N205786-001PED2021-05-22ea99ee380514…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ISENTRESSRALTEGRAVIRMerck Sharp & Dohme LLC89a5ec53-d956-4329-8004-0f40f51c88a32024-10-18Warnings, Adverse reactionsExact identifier
application applno (NDA): 205786
application number: NDA205786
ndc (product): 0006-3603

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 6 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme Corp.NDACurrent
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme Corp.NDACurrent
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme LLCNDACurrent
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme LLCNDACurrent
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme Corp.NDACurrent
0006-3603ISENTRESSRALTEGRAVIRMerck Sharp & Dohme Corp.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
67559SUPPL2021-05-20
67555SUPPL2021-05-19
63958SUPPL2020-07-17
63942SUPPL2020-07-16
53011SUPPL2018-03-15
52827SUPPL2018-03-06
50506SUPPL2017-12-06
50476SUPPL2017-11-24
48597SUPPL2017-05-31
48577SUPPL2017-05-31
32726SUPPL2015-02-24
40504SUPPL2015-02-23
40503SUPPL2015-02-20
32725SUPPL2015-02-19
43503ORIG2014-06-27
24504ORIG2014-06-27
40502SUPPL2014-04-10
32724SUPPL2014-04-10
10502ORIG2013-12-31
40501ORIG2013-12-23
64577ORIG1900-01-01
63240SUPPL1900-01-01
63239SUPPL1900-01-01
51470ORIG1900-01-01
51469ORIG1900-01-01