Application 205858

Type: NDA
Sponsor: GILEAD SCIENCES INC

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	ZYDELIG	IDELALISIB	TABLET;ORAL	100MG	Yes	No
002	ZYDELIG	IDELALISIB	TABLET;ORAL	150MG	Yes	Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N205858-001	ZYDELIG	IDELALISIB	100MG	TABLET / ORAL	AB	RLD	2014-07-23
N205858-002	ZYDELIG	IDELALISIB	150MG	TABLET / ORAL	AB	RLD, RS	2014-07-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-product	TE code
N205858-001	AB
N205858-002	AB

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N205858-001	9492449	2030-03-11	U-1914		2016-11-16
N205858-001	10730879	2033-03-05		Drug substance, Drug product	2020-09-03
N205858-001	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18
N205858-001	9469643	2033-09-02		Drug substance	2016-11-16
N205858-002	9492449	2030-03-11	U-1914		2016-11-16
N205858-002	10730879	2033-03-05		Drug substance, Drug product	2020-09-03
N205858-002	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18
N205858-002	9469643	2033-09-02		Drug substance	2016-11-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N205858-001	ZYDELIG	100MG	TABLET / ORAL	AB	RLD	2014-07-23	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	ZYDELIG	150MG	TABLET / ORAL	AB	RLD, RS	2014-07-23	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N205858-001	ZYDELIG	100MG	TABLET / ORAL	AB	RLD	2014-07-23	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	ZYDELIG	150MG	TABLET / ORAL	AB	RLD, RS	2014-07-23	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N205858-001	ZYDELIG	100MG	TABLET / ORAL		RLD	2014-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-002	ZYDELIG	150MG	TABLET / ORAL		RLD, RS	2014-07-23	`74a2ff9319b5…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	N205858-001	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	AB	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N205858-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	AB	1	`caaa826d4ba7…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N205858-001	AB	1	`a50c72e98297…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N205858-002	AB	1	`a50c72e98297…`

Observed Orange Book patent history#

Patent history page 1 of 21 · 816 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-09-14 22:38:34	2026-08	N205858-001	9492449	2030-03-11	U-1914		2016-11-16	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-001	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-001	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-001	9469643	2033-09-02		Drug substance	2016-11-16	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	9492449	2030-03-11	U-1914		2016-11-16	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N205858-002	9469643	2033-09-02		Drug substance	2016-11-16	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N205858-001	9492449	2030-03-11	U-1914		2016-11-16	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-001	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-001	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-001	9469643	2033-09-02		Drug substance	2016-11-16	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	9492449	2030-03-11	U-1914		2016-11-16	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N205858-002	9469643	2033-09-02		Drug substance	2016-11-16	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N205858-001	9492449	2030-03-11	U-1914		2016-11-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-001	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-001	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-001	9469643	2033-09-02		Drug substance	2016-11-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-002	9492449	2030-03-11	U-1914		2016-11-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-002	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-002	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N205858-002	9469643	2033-09-02		Drug substance	2016-11-16	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	8980901	2025-05-12	U-1678		2015-04-10	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	9149477	2025-05-12	U-1757		2015-11-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	RE44599	2025-07-21	U-1558		2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	RE44599	2025-07-21	U-1615		2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	RE44638	2025-08-05		Drug substance, Drug product	2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	9492449	2030-03-11	U-1914		2016-11-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	8865730	2033-03-05	U-1615	Drug substance, Drug product	2014-11-18	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-001	9469643	2033-09-02		Drug substance	2016-11-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	8980901	2025-05-12	U-1678		2015-04-10	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	9149477	2025-05-12	U-1757		2015-11-03	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	RE44599	2025-07-21	U-1615		2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	RE44599	2025-07-21	U-1558		2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	RE44638	2025-08-05		Drug substance, Drug product	2014-08-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	9492449	2030-03-11	U-1914		2016-11-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N205858-002	10730879	2033-03-05		Drug substance, Drug product	2020-09-03	`31067a03dcf5…`

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 44 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Exclusivity code	Expiration	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N205858-001	NCE	2019-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-001	ODE-70	2021-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-001	ODE-71	2021-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-002	NCE	2019-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-002	ODE-70	2021-07-23	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N205858-002	ODE-71	2021-07-23	`74a2ff9319b5…`
2021-12-28 21:50 UTC	2021-12	N205858-001	ODE-70	2021-07-23	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N205858-001	ODE-71	2021-07-23	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N205858-002	ODE-70	2021-07-23	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N205858-002	ODE-71	2021-07-23	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N205858-001	ODE-70	2021-07-23	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N205858-001	ODE-71	2021-07-23	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N205858-002	ODE-70	2021-07-23	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N205858-002	ODE-71	2021-07-23	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N205858-001	ODE-70	2021-07-23	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	N205858-001	ODE-71	2021-07-23	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	N205858-002	ODE-70	2021-07-23	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	N205858-002	ODE-71	2021-07-23	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N205858-001	ODE-70	2021-07-23	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N205858-001	ODE-71	2021-07-23	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N205858-002	ODE-70	2021-07-23	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	N205858-002	ODE-71	2021-07-23	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N205858-001	ODE-70	2021-07-23	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N205858-001	ODE-71	2021-07-23	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N205858-002	ODE-70	2021-07-23	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	N205858-002	ODE-71	2021-07-23	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N205858-001	NCE	2019-07-23	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N205858-001	ODE-70	2021-07-23	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N205858-001	ODE-71	2021-07-23	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N205858-002	NCE	2019-07-23	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N205858-002	ODE-70	2021-07-23	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	N205858-002	ODE-71	2021-07-23	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N205858-001	NCE	2019-07-23	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N205858-001	ODE-70	2021-07-23	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N205858-001	ODE-71	2021-07-23	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N205858-002	NCE	2019-07-23	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N205858-002	ODE-70	2021-07-23	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	N205858-002	ODE-71	2021-07-23	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N205858-001	NCE	2019-07-23	`ea99ee380514…`
2019-07-19 19:46 UTC	2019-07	N205858-001	ODE-70	2021-07-23	`ea99ee380514…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 6 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
61958-1701	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current
61958-1701	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current
61958-1701	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current
61958-1702	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current
61958-1702	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current
61958-1702	Zydelig	idelalisib	Gilead Sciences, Inc.	NDA	Current

Documents#

Document, Submission type, Date table
Document	Submission type	Date
71527	SUPPL	2022-07-07
70483	SUPPL	2022-03-11
70210	SUPPL	2022-02-22
70198	SUPPL	2022-02-22
70197	SUPPL	2022-02-22
64963	SUPPL	2020-10-21
64955	SUPPL	2020-10-21
64954	SUPPL	2020-10-21
57113	SUPPL	2019-01-30
55897	SUPPL	2018-10-11
53502	SUPPL	2018-03-28
52518	SUPPL	2018-02-08
52509	SUPPL	2018-02-08
52400	SUPPL	2018-02-05
52399	SUPPL	2018-02-05
52127	SUPPL	2018-01-30
52083	SUPPL	2018-01-30
50567	SUPPL	2017-12-01
50529	SUPPL	2017-11-30
46678	SUPPL	2017-01-05
45411	SUPPL	2016-09-29
45362	SUPPL	2016-09-22
44935	ORIG	2015-02-06
23007	ORIG	2015-02-06
44599	ORIG	2014-08-01
10520	ORIG	2014-07-24
40518	ORIG	2014-07-23