Application 207500

Type
NDA
Sponsor
ASTELLAS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001CRESEMBAISAVUCONAZONIUM SULFATECAPSULE;ORAL186MGYesYes
002CRESEMBAISAVUCONAZONIUM SULFATECAPSULE;ORAL74.5MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N207500-001CRESEMBAISAVUCONAZONIUM SULFATE186MGCAPSULE / ORALRLD, RS2015-03-06
N207500-002CRESEMBAISAVUCONAZONIUM SULFATE74.5MGCAPSULE / ORALRLD2022-11-22

Orange Book patents#

Current patent rows page 1 of 1 · 12 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N207500-00168122382025-10-31Drug substance2015-04-01
N207500-0016812238*PED2026-04-30Pediatric extension
N207500-001102068792027-09-14Drug product2021-12-03
N207500-001106032802027-09-14Drug product2021-12-03
N207500-00110206879*PED2028-03-14Pediatric extension
N207500-00110603280*PED2028-03-14Pediatric extension
N207500-00268122382025-10-31Drug substance2023-06-29
N207500-0026812238*PED2026-04-30Pediatric extension
N207500-002102068792027-09-14Drug product2022-12-21
N207500-002106032802027-09-14Drug product2022-12-21
N207500-00210206879*PED2028-03-14Pediatric extension
N207500-00210603280*PED2028-03-14Pediatric extension

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 21 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N207500-001ODE-3052022-03-06
N207500-001ODE-902022-03-06
N207500-001PED2022-09-06
N207500-001PED2022-09-06
N207500-001NPP2026-12-08
N207500-001PED2027-06-08
N207500-001GAIN2027-09-06
N207500-001GAIN2027-09-06
N207500-001ODE-4542030-12-08
N207500-001ODE-4582030-12-08
N207500-001PED2031-06-08
N207500-001PED2031-06-08
N207500-002ODE*2022-03-06
N207500-002PED2022-09-06
N207500-002NPP2026-12-08
N207500-002PED2027-06-08
N207500-002GAIN2027-09-06
N207500-002ODE-4542030-12-08
N207500-002ODE-4582030-12-08
N207500-002PED2031-06-08
N207500-002PED2031-06-08

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 65 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-066a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-0603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-2203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-062680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-222680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-065bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-225bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06d06236e962d9…
2024-10-29 15:01 UTC2024-10N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-0679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-2279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-22301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-061e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-221e350fbaab3a…
2024-05-31 18:47 UTC2024-05N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-068072bd15b7f6…
2024-05-31 18:47 UTC2024-05N207500-002CRESEMBA74.5MGCAPSULE / ORALRLD2022-11-228072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-065c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-065d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-064b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-0674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-0687673890dc5c…
2021-03-12 10:30 UTC2021-03N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-065aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-068869cabd3fbd…
2020-11-12 02:37 UTC2020-11N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06c0c555d07b60…
2019-12-14 00:12 UTC2019-12N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-063f01610625f2…
2019-09-15 20:21 UTC2019-09N207500-001CRESEMBA186MGCAPSULE / ORALRLD, RS2015-03-06b00525d2431f…

Observed Orange Book patent history#

Patent history page 1 of 8 · 293 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N207500-00168122382025-10-31Drug substance2015-04-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-0016812238*PED2026-04-30Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001102068792027-09-14Drug product2021-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001106032802027-09-14Drug product2021-12-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-00110206879*PED2028-03-14Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-00110603280*PED2028-03-14Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-00268122382025-10-31Drug substance2023-06-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-0026812238*PED2026-04-30Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002102068792027-09-14Drug product2022-12-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002106032802027-09-14Drug product2022-12-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-00210206879*PED2028-03-14Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-00210603280*PED2028-03-14Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00168122382025-10-31Drug substance2015-04-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-0016812238*PED2026-04-30Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001102068792027-09-14Drug product2021-12-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001106032802027-09-14Drug product2021-12-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00110206879*PED2028-03-14Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00110603280*PED2028-03-14Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00268122382025-10-31Drug substance2023-06-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-0026812238*PED2026-04-30Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002102068792027-09-14Drug product2022-12-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002106032802027-09-14Drug product2022-12-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00210206879*PED2028-03-14Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-00210603280*PED2028-03-14Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N207500-00168122382025-10-31Drug substance2015-04-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-0016812238*PED2026-04-30Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-001102068792027-09-14Drug product2021-12-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-001106032802027-09-14Drug product2021-12-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-00110206879*PED2028-03-14Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-00110603280*PED2028-03-14Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-00268122382025-10-31Drug substance2023-06-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-0026812238*PED2026-04-30Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-002102068792027-09-14Drug product2022-12-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-002106032802027-09-14Drug product2022-12-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-00210206879*PED2028-03-14Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N207500-00210603280*PED2028-03-14Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-00168122382025-10-31Drug substance2015-04-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-0016812238*PED2026-04-30Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-001102068792027-09-14Drug product2021-12-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207500-001106032802027-09-14Drug product2021-12-03fd3edfee7708…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 16 · 602 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N207500-001ODE-3052022-03-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001ODE-902022-03-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001PED2022-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001PED2022-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001NPP2026-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001PED2027-06-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001GAIN2027-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001GAIN2027-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001ODE-4542030-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001ODE-4582030-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001PED2031-06-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-001PED2031-06-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002ODE*2022-03-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002PED2022-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002NPP2026-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002PED2027-06-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002GAIN2027-09-06011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002ODE-4542030-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002ODE-4582030-12-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002PED2031-06-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N207500-002PED2031-06-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001NCE2020-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2020-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001ODE-3052022-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001ODE-902022-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2022-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2022-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001GAIN2025-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001NPP2026-12-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2027-06-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001GAIN2027-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001GAIN2027-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001ODE-4542030-12-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001ODE-4582030-12-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2031-06-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-001PED2031-06-0831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002NCE2020-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002PED2020-09-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002ODE*2022-03-0631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207500-002PED2022-09-0631067a03dcf5…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CRESEMBAISAVUCONAZONIUM SULFATEAstellas Pharma US, Inc.8f7f73b8-586a-4df0-935f-fecd4696c16c2025-04-25Warnings, Adverse reactionsExact identifier
application applno (NDA): 207500
application number: NDA207500
ndc (product): 0469-2860
ndc (product): 0469-0520

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 12 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-0520CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-2860CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent
0469-2860CRESEMBAisavuconazonium sulfateAstellas Pharma US, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81730SUPPL 2025-03-25
81727SUPPL 2025-03-25
76760SUPPL 2023-12-11
76754SUPPL 2023-12-11
73956SUPPL 2023-04-06
70204SUPPL2022-02-22
70191SUPPL2022-02-18
69545SUPPL2021-12-14
69531SUPPL2021-12-13
67549SUPPL2021-05-19
67545SUPPL2021-05-19
67178SUPPL2021-04-26
67165SUPPL2021-04-23
61225SUPPL2019-12-11
61202SUPPL2019-12-10
19962SUPPL2015-04-28
32854SUPPL2015-04-06
44958ORIG2015-04-03
43533ORIG2015-04-03
40586ORIG2015-03-06
32853ORIG2015-03-06