Home Applications 208144 Application 208144
Type NDA
Sponsor BAUSCH AND LOMB INC Application Products# Product, Drug, Ingredient table Product Drug Ingredient Form Strength Reference drug Reference standard 001 LUMIFY BRIMONIDINE TARTRATE SOLUTION/DROPS;OPHTHALMIC 0.025% Yes Yes
Source provenance: Browse the complete Orange Book source catalog · source snapshot 43 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N208144-001 LUMIFY BRIMONIDINE TARTRATE 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22
Orange Book patents# Current patent rows page 1 of 1 · 5 matching rows.
Application-product, Patent, Expiration table Application-product Patent Expiration Use code Coverage / status Submission date N208144-001 11596600 2029-07-27 U-2222 2023-03-27 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 N208144-001 12514857 2029-07-27 U-2222 2026-09-02 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 N208144-001 9259425 2030-07-14 U-2222 2021-07-27
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 43 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-09-14 22:38:34 2026-08 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 84e616aacf4f…2026-08-18 06:07:40 2026-07 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N208144-001 LUMIFY 0.025% SOLUTION/DROPS / OPHTHALMIC RLD, RS 2017-12-22 f41ea6bd6efb…
Observed Orange Book patent history# Patent history page 1 of 4 · 123 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2026-09-14 22:38:34 2026-08 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 84e616aacf4f…2026-09-14 22:38:34 2026-08 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 84e616aacf4f…2026-09-14 22:38:34 2026-08 N208144-001 12514857 2029-07-27 U-2222 2026-09-02 84e616aacf4f…2026-09-14 22:38:34 2026-08 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 84e616aacf4f…2026-09-14 22:38:34 2026-08 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 84e616aacf4f…2026-08-18 06:07:40 2026-07 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 caaa826d4ba7…2026-08-18 06:07:40 2026-07 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N208144-001 9259425 2030-07-14 U-2222 2021-07-27 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N208144-001 11596600 2029-07-27 U-2222 2023-03-27 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N208144-001 11833245 2029-07-27 U-2222 2023-12-12 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N208144-001 8293742 2030-07-14 U-2222 2018-01-26 5bbf6a4d5a75…
Observed Orange Book exclusivity history# openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
NDC Listings For This Application# NDC listings for this application page 1 of 1 · 10 matching rows.
NDC, Name, Nonproprietary name table NDC Name Nonproprietary name Labeler Marketing category Status 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current 24208-537 LUMIFY Redness Reliever Eye Drops BRIMONIDINE TARTRATE Bausch & Lomb Incorporated NDA Current