Application 208261

Type
NDA
Sponsor
MERCK SHARP DOHME

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ZEPATIERELBASVIR; GRAZOPREVIRTABLET;ORAL50MG;100MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208261-001ZEPATIERELBASVIR; GRAZOPREVIR50MG;100MGTABLET / ORALRLD2016-01-28

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N208261-00179730402029-07-24U-1813Drug substance, Drug product2016-02-25
N208261-00188717592031-05-04U-1813Drug substance, Drug product2016-02-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N208261-001ZEPATIER50MG;100MGTABLET / ORALRLD2016-01-28a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-01 22:54:322026-06N208261-00179730402029-07-24U-1813Drug substance, Drug product2016-02-25a50c72e98297…
2026-08-01 22:54:322026-06N208261-00188717592031-05-04U-1813Drug substance, Drug product2016-02-25a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ZEPATIERELBASVIR AND GRAZOPREVIRMerck Sharp & Dohme LLC164dc02a-9180-426a-b8b5-04ab39d2bbd42026-03-13Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 208261
application number: NDA208261
ndc (product): 0006-3074

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 7 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme LLCNDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent
0006-3074ZEPATIERelbasvir and grazoprevirMerck Sharp & Dohme Corp.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
69552SUPPL2021-12-14
69533SUPPL2021-12-13
61255SUPPL2019-12-12
61242SUPPL2019-12-12
54827SUPPL2018-07-06
54772SUPPL2018-07-05
50402SUPPL2017-11-14
50383SUPPL2017-11-13
47245SUPPL2017-02-16
47244SUPPL2017-02-16
46853SUPPL2017-01-17
46806SUPPL2017-01-11
44973ORIG2016-03-08
43545ORIG2016-03-08
19989ORIG2016-02-02
10652ORIG2016-01-29