Application 208328

Type
ANDA
Sponsor
AMNEAL PHARMS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDECAPSULE, EXTENDED RELEASE;ORAL10MG;14MGNoNo
002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDECAPSULE, EXTENDED RELEASE;ORAL10MG;28MGNoNo
003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDECAPSULE, EXTENDED RELEASE;ORAL10MG;7MGNoNo
004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDECAPSULE, EXTENDED RELEASE;ORAL10MG;21MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27
A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27
A208328-003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDE10MG;7MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27
A208328-004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDEDONEPEZIL HYDROCHLORIDE; MEMANTINE HYDROCHLORIDE10MG;21MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
A208328-001AB
A208328-002AB
A208328-003AB
A208328-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 92 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;7MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;21MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;7MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;21MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;7MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;21MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-003MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;7MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-004MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;21MGCAPSULE, EXTENDED RELEASE / ORALAB2025-02-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORALAB2017-01-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-278072bd15b7f6…
2024-05-31 18:47 UTC2024-05A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A208328-001MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;14MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A208328-002MEMANTINE HYDROCHLORIDE AND DONEPEZIL HYDROCHLORIDE10MG;28MGCAPSULE, EXTENDED RELEASE / ORAL2017-01-275d02ea3f76ae…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A208328-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A208328-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A208328-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208328-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A208328-002AB103ed91905a0d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A208328-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A208328-002AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A208328-003AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A208328-004AB1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-001PC2025-07-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A208328-002PC2025-07-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08A208328-001PC2025-07-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08A208328-002PC2025-07-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-001PC2025-07-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A208328-002PC2025-07-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-001PC2025-07-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A208328-002PC2025-07-15b8a1b40f171c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Memantine and Donepezil Hydrochlorides Extended-releaseMEMANTINE AND DONEPEZILAvKARE2d821427-34ca-3c5d-e063-6394a90a90132025-02-06Warnings, Adverse reactionsExact identifier
application applno (ANDA): 208328
application number: ANDA208328
Memantine and Donepezil Hydrochlorides Extended-releaseMEMANTINE AND DONEPEZILAmneal Pharmaceuticals NY LLC2335950c-be3b-4248-ad04-e9763aee47d22024-12-17Warnings, Adverse reactionsExact identifier
application applno (ANDA): 208328
application number: ANDA208328
ndc (product): 69238-1248
ndc (product): 69238-1247
ndc (product): 69238-1553
ndc (product): 69238-1552

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 18 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
69238-1247Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1247Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1247Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1247Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals LLCANDACurrent
69238-1247Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1248Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1248Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1248Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1248Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals LLCANDACurrent
69238-1248Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1552Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1552Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1552Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1552Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1553Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1553Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1553Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent
69238-1553Memantine and Donepezil Hydrochlorides Extended-releaseMemantine and DonepezilAmneal Pharmaceuticals NY LLCANDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
47076ORIG2017-01-31
47057ORIG2017-01-31