Application 208716

Type
NDA
Sponsor
ELI LILLY AND CO

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001VERZENIOABEMACICLIBTABLET;ORAL50MGYesNo
002VERZENIOABEMACICLIBTABLET;ORAL100MGYesNo
003VERZENIOABEMACICLIBTABLET;ORAL150MGYesNo
004VERZENIOABEMACICLIBTABLET;ORAL200MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208716-001VERZENIOABEMACICLIB50MGTABLET / ORALRLD2017-09-28
N208716-002VERZENIOABEMACICLIB100MGTABLET / ORALRLD2017-09-28
N208716-003VERZENIOABEMACICLIB150MGTABLET / ORALRLD2017-09-28
N208716-004VERZENIOABEMACICLIB200MGTABLET / ORALRLD, RS2017-09-28

Orange Book patents#

Current patent rows page 1 of 1 · 17 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N208716-00178552112031-09-28U-2135Drug substance, Drug product2017-10-16
N208716-00178552112031-09-28U-3242Drug substance, Drug product2017-10-16
N208716-00178552112031-09-28U-3265Drug substance, Drug product2017-10-16
N208716-00178552112031-09-28U-3546Drug substance, Drug product2017-10-16
N208716-00278552112031-09-28U-2135Drug substance, Drug product2017-10-16
N208716-00278552112031-09-28U-3242Drug substance, Drug product2017-10-16
N208716-00278552112031-09-28U-3265Drug substance, Drug product2017-10-16
N208716-00278552112031-09-28U-3546Drug substance, Drug product2017-10-16
N208716-00378552112031-09-28U-2135Drug substance, Drug product2017-10-16
N208716-00378552112031-09-28U-3242Drug substance, Drug product2017-10-16
N208716-00378552112031-09-28U-3265Drug substance, Drug product2017-10-16
N208716-00378552112031-09-28U-3546Drug substance, Drug product2017-10-16
N208716-00478552112031-09-28U-1981Drug substance, Drug product2017-10-16
N208716-00478552112031-09-28U-2135Drug substance, Drug product2017-10-16
N208716-00478552112031-09-28U-3242Drug substance, Drug product2017-10-16
N208716-00478552112031-09-28U-3265Drug substance, Drug product2017-10-16
N208716-00478552112031-09-28U-3546Drug substance, Drug product2017-10-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 172 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-2884e616aacf4f…
2026-09-14 22:38:342026-08N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-2884e616aacf4f…
2026-09-14 22:38:342026-08N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-2884e616aacf4f…
2026-09-14 22:38:342026-08N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-2884e616aacf4f…
2026-08-18 06:07:402026-07N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-28caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-28caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-28caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-001VERZENIO50MGTABLET / ORALRLD2017-09-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-002VERZENIO100MGTABLET / ORALRLD2017-09-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-003VERZENIO150MGTABLET / ORALRLD2017-09-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-004VERZENIO200MGTABLET / ORALRLD, RS2017-09-285bbf6a4d5a75…

Observed Orange Book patent history#

Patent history page 1 of 23 · 881 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-09-14 22:38:342026-08N208716-00178552112031-09-28U-2135Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00178552112031-09-28U-3546Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00178552112031-09-28U-3265Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00178552112031-09-28U-3242Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00278552112031-09-28U-2135Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00278552112031-09-28U-3546Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00278552112031-09-28U-3265Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00278552112031-09-28U-3242Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00378552112031-09-28U-2135Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00378552112031-09-28U-3546Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00378552112031-09-28U-3265Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00378552112031-09-28U-3242Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00478552112031-09-28U-1981Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00478552112031-09-28U-2135Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00478552112031-09-28U-3265Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00478552112031-09-28U-3546Drug substance, Drug product2017-10-1684e616aacf4f…
2026-09-14 22:38:342026-08N208716-00478552112031-09-28U-3242Drug substance, Drug product2017-10-1684e616aacf4f…
2026-08-18 06:07:402026-07N208716-00178552112031-09-28U-2135Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00178552112031-09-28U-3546Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00178552112031-09-28U-3265Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00178552112031-09-28U-3242Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00278552112031-09-28U-2135Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00278552112031-09-28U-3546Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00278552112031-09-28U-3265Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00278552112031-09-28U-3242Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00378552112031-09-28U-2135Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00378552112031-09-28U-3546Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00378552112031-09-28U-3265Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00378552112031-09-28U-3242Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00478552112031-09-28U-1981Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00478552112031-09-28U-2135Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00478552112031-09-28U-3265Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00478552112031-09-28U-3546Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N208716-00478552112031-09-28U-3242Drug substance, Drug product2017-10-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N208716-00178552112031-09-28U-2135Drug substance, Drug product2017-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-00178552112031-09-28U-3546Drug substance, Drug product2017-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-00178552112031-09-28U-3265Drug substance, Drug product2017-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-00178552112031-09-28U-3242Drug substance, Drug product2017-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-00278552112031-09-28U-2135Drug substance, Drug product2017-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208716-00278552112031-09-28U-3546Drug substance, Drug product2017-10-16011fe1cb6892…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 9 · 324 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-001I-8772024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-001NPP2024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-002I-8772024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-002NPP2024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-003I-8772024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-003NPP2024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-004I-8772024-10-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208716-004NPP2024-10-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-001I-8772024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-001NPP2024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-002I-8772024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-002NPP2024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-003I-8772024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-003NPP2024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-004I-8772024-10-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208716-004NPP2024-10-122680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-001I-8772024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-001NPP2024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-002I-8772024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-002NPP2024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-003I-8772024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-003NPP2024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-004I-8772024-10-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208716-004NPP2024-10-125bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-001I-8772024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-001NPP2024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-002I-8772024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-002NPP2024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-003I-8772024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-003NPP2024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-004I-8772024-10-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208716-004NPP2024-10-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208716-001I-8772024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-001NPP2024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-002I-8772024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-002NPP2024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-003I-8772024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-003NPP2024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-004I-8772024-10-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N208716-004NPP2024-10-12d06236e962d9…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
VerzenioABEMACICLIBEli Lilly and Companybe4bc0de-0fdc-4d46-8d25-be43c79e6a062026-07-13Warnings, Adverse reactionsExact identifier
application applno (NDA): 208716
application number: NDA208716
ndc (product): 0002-5337
ndc (product): 0002-4483
ndc (product): 0002-4815
ndc (product): 0002-6216

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 24 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4483VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-4815VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-5337VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent
0002-6216VerzenioabemaciclibEli Lilly and CompanyNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81385SUPPL 2025-03-03
81381SUPPL 2025-02-28
80215SUPPL 2024-11-14
80213SUPPL 2024-11-14
73682SUPPL 2023-03-06
73681SUPPL 2023-03-06
73674SUPPL 2023-03-03
73673SUPPL 2023-03-03
68982SUPPL2021-10-14
68981SUPPL2021-10-14
68980SUPPL2021-10-14
68967SUPPL2021-10-13
68966SUPPL2021-10-13
68965SUPPL2021-10-13
62406SUPPL2020-04-01
62394SUPPL2020-03-31
59972SUPPL2019-09-11
59957SUPPL2019-09-09
55257SUPPL2018-08-21
55214SUPPL2018-08-20
50236ORIG2017-10-31
49891ORIG2017-09-28
49872ORIG2017-09-28