Application 210115

Type
NDA
Sponsor
ASTELLAS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001PROGRAFTACROLIMUSFOR SUSPENSION;ORALEQ 0.2MG BASE/PACKETYesNo
002PROGRAFTACROLIMUSFOR SUSPENSION;ORALEQ 1MG BASE/PACKETYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N210115-001PROGRAFTACROLIMUSEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24
N210115-002PROGRAFTACROLIMUSEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N210115-001ODE-3602028-07-16
N210115-002ODE-3602028-07-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24caaa826d4ba7…
2026-08-18 06:07:402026-07N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24d06236e962d9…
2024-10-29 15:01 UTC2024-10N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-2479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-241e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-248072bd15b7f6…
2024-05-31 18:47 UTC2024-05N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-245c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-245d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-244b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-2474a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210115-001PROGRAFEQ 0.2MG BASE/PACKETFOR SUSPENSION / ORALRLD2018-05-24bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210115-002PROGRAFEQ 1MG BASE/PACKETFOR SUSPENSION / ORALRLD, RS2018-05-24bb7c543d1eb4…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 4 · 140 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-18 06:07:402026-07N210115-001ODE-3602028-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N210115-002ODE-3602028-07-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210115-001ODE-3602028-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210115-002ODE-3602028-07-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-001ODE-2692025-05-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-001ODE-3602028-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-002ODE-2692025-05-2431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210115-002ODE-3602028-07-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N210115-001ODE-2692025-05-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210115-001ODE-3602028-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210115-002ODE-2692025-05-246a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210115-002ODE-3602028-07-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-001ODE-2692025-05-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-001ODE-3602028-07-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-002ODE-2692025-05-24fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210115-002ODE-3602028-07-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-001ODE-2692025-05-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-001ODE-3602028-07-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-002ODE-2692025-05-24b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210115-002ODE-3602028-07-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-001ODE-2692025-05-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-001ODE-3602028-07-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-002ODE-2692025-05-2403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210115-002ODE-3602028-07-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-001ODE-2692025-05-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-001ODE-3602028-07-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-002ODE-2692025-05-242680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210115-002ODE-3602028-07-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-001ODE-2692025-05-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-001ODE-3602028-07-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-002ODE-2692025-05-245bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210115-002ODE-3602028-07-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-001ODE-2692025-05-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-001ODE-3602028-07-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-002ODE-2692025-05-24d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210115-002ODE-3602028-07-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210115-001ODE-2692025-05-24d06236e962d9…
2024-10-29 15:01 UTC2024-10N210115-001ODE-3602028-07-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N210115-002ODE-2692025-05-24d06236e962d9…
2024-10-29 15:01 UTC2024-10N210115-002ODE-3602028-07-16d06236e962d9…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PrografTACROLIMUSAstellas Pharma US, Inc.7f667de1-9dfa-4bd6-8ba0-15ee2d78873b2023-08-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 210115
application number: NDA210115
ndc (product): 0469-1330
ndc (product): 0469-1230

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 14 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1230PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent
0469-1330PrografTacrolimusAstellas Pharma US, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
75496SUPPL 2023-09-15
75478SUPPL 2023-09-15
72705SUPPL2022-11-25
72686SUPPL2022-11-23
72685SUPPL2022-11-23
71268SUPPL2022-06-13
68118SUPPL2021-07-19
68102SUPPL2021-07-16
65800SUPPL2020-12-31
65787SUPPL2020-12-31
59032SUPPL2019-06-12
56672SUPPL2018-12-07
56582ORIG2018-11-28
54352ORIG2018-05-29
54346ORIG2018-05-29