Application 210238

Type
NDA
Sponsor
AKARX INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001DOPTELETAVATROMBOPAG MALEATETABLET;ORALEQ 20MG BASEYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N210238-001DOPTELETAVATROMBOPAG MALEATEEQ 20MG BASETABLET / ORALRLD, RS2018-05-21

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N210238-00176385362027-07-28Drug substance, Drug product2018-06-15

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 3 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N210238-001ODE-2462026-06-26
N210238-001I-9742028-07-24
N210238-001ODE-5482032-07-24

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2184e616aacf4f…
2026-08-18 06:07:402026-07N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-214b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-2187673890dc5c…
2021-03-12 10:30 UTC2021-03N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-215aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-218869cabd3fbd…
2020-11-12 02:37 UTC2020-11N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21c0c555d07b60…
2019-12-14 00:12 UTC2019-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-213f01610625f2…
2019-09-15 20:21 UTC2019-09N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21b00525d2431f…
2019-07-19 19:46 UTC2019-07N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-211c564ffb4f44…
2023-12-20 04:57 UTC2023-12N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-213f0d92c62455…
2023-05-13 08:27 UTC2023-05N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21053a50430f4f…
2023-01-26 05:58 UTC2023-01N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-213bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-213a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N210238-001DOPTELETEQ 20MG BASETABLET / ORALRLD, RS2018-05-21f41ea6bd6efb…

Observed Orange Book patent history#

Patent history page 1 of 3 · 113 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-09-14 22:38:342026-08N210238-00176385362027-07-28Drug substance, Drug product2018-06-1584e616aacf4f…
2026-08-18 06:07:402026-07N210238-00176385362027-07-28Drug substance, Drug product2018-06-15caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210238-00176385362027-07-28Drug substance, Drug product2018-06-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210238-00176385362027-07-28Drug substance, Drug product2018-06-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N210238-00176385362027-07-28Drug substance, Drug product2018-06-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210238-00176385362027-07-28Drug substance, Drug product2018-06-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210238-00176385362027-07-28Drug substance, Drug product2018-06-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210238-00176385362027-07-28Drug substance, Drug product2018-06-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210238-00176385362027-07-28Drug substance, Drug product2018-06-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210238-00176385362027-07-28Drug substance, Drug product2018-06-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210238-00176385362027-07-28Drug substance, Drug product2018-06-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210238-00176385362027-07-28Drug substance, Drug product2018-06-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210238-00176385362027-07-28Drug substance, Drug product2018-06-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210238-00176385362027-07-28Drug substance, Drug product2018-06-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210238-00176385362027-07-28Drug substance, Drug product2018-06-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210238-00176385362027-07-28Drug substance, Drug product2018-06-158072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-00187657642023-01-15U-23142018-06-155c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-00187657642023-01-15U-25782018-06-155c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-00183384292023-06-30U-25772019-07-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-00176385362025-05-05Drug substance, Drug product2018-06-155c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210238-00187657642023-01-15U-23142018-06-155d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210238-00187657642023-01-15U-25782018-06-155d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210238-00183384292023-06-30U-25772019-07-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210238-00176385362025-05-05Drug substance, Drug product2018-06-155d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210238-00187657642023-01-15U-23142018-06-154b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210238-00187657642023-01-15U-25782018-06-154b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210238-00183384292023-06-30U-25772019-07-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210238-00176385362025-05-05Drug substance, Drug product2018-06-154b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210238-00187657642023-01-15U-25782018-06-1574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210238-00187657642023-01-15U-23142018-06-1574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210238-00183384292023-06-30U-25772019-07-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210238-00176385362025-05-05Drug substance, Drug product2018-06-1574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210238-00187657642023-01-15U-25782018-06-15bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210238-00187657642023-01-15U-23142018-06-15bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210238-00183384292023-06-30U-25772019-07-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210238-00176385362025-05-05Drug substance, Drug product2018-06-15bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210238-00187657642023-01-15U-23142018-06-15782e0a99824c…
2021-12-28 21:50 UTC2021-12N210238-00187657642023-01-15U-25782018-06-15782e0a99824c…
2021-12-28 21:50 UTC2021-12N210238-00183384292023-06-30U-25772019-07-25782e0a99824c…
2021-12-28 21:50 UTC2021-12N210238-00176385362025-05-05Drug substance, Drug product2018-06-15782e0a99824c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 3 · 91 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-09-14 22:38:342026-08N210238-001ODE-2462026-06-2684e616aacf4f…
2026-09-14 22:38:342026-08N210238-001I-9742028-07-2484e616aacf4f…
2026-09-14 22:38:342026-08N210238-001ODE-5482032-07-2484e616aacf4f…
2026-08-18 06:07:402026-07N210238-001ODE-2462026-06-26caaa826d4ba7…
2026-08-18 06:07:402026-07N210238-001I-9742028-07-24caaa826d4ba7…
2026-08-18 06:07:402026-07N210238-001ODE-5482032-07-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N210238-001ODE-2462026-06-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210238-001I-9742028-07-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210238-001ODE-2462026-06-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210238-001I-9742028-07-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N210238-001ODE-2462026-06-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210238-001ODE-2462026-06-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210238-001ODE-2462026-06-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210238-001ODE-2462026-06-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210238-001ODE-2462026-06-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210238-001ODE-2462026-06-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210238-001ODE-2462026-06-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210238-001ODE-2462026-06-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210238-001ODE-2462026-06-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210238-001ODE-2462026-06-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210238-001ODE-2462026-06-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210238-001ODE-2462026-06-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-001I-8022022-06-265c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-001NCE2023-05-215c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210238-001ODE-2462026-06-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210238-001I-8022022-06-265d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210238-001NCE2023-05-215d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210238-001ODE-2462026-06-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210238-001I-8022022-06-264b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210238-001NCE2023-05-214b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210238-001ODE-2462026-06-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N210238-001I-8022022-06-2674a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210238-001NCE2023-05-2174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N210238-001ODE-2462026-06-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N210238-001I-8022022-06-26bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210238-001NCE2023-05-21bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210238-001ODE-2462026-06-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210238-001I-8022022-06-26782e0a99824c…
2021-12-28 21:50 UTC2021-12N210238-001NCE2023-05-21782e0a99824c…
2021-12-28 21:50 UTC2021-12N210238-001ODE-2462026-06-26782e0a99824c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Doptelet SprinkleAVATROMBOPAGAkaRx, Inc.e2d5960d-6c18-46cc-86bd-089222b098522025-08-13Warnings, Adverse reactionsExact identifier
application applno (NDA): 210238
application number: NDA210238
ndc (product): 71369-020

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 8 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent
71369-020DOPTELETavatrombopag maleateAkaRx, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82962SUPPL 2026-05-12
82941SUPPL 2025-07-25
79147SUPPL 2024-07-22
79130SUPPL 2024-07-22
69024SUPPL2021-10-19
68999SUPPL2021-10-15
64378SUPPL2020-08-24
64345SUPPL2020-08-21
59193SUPPL2019-06-28
59187SUPPL2019-06-20
58066SUPPL2019-03-22
54724ORIG2018-06-28
54319ORIG2018-05-24
54258ORIG2018-05-21