Application 211349

Type
NDA
Sponsor
ASTELLAS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001XOSPATAGILTERITINIB FUMARATETABLET;ORALEQ 40MG BASEYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N211349-001XOSPATAGILTERITINIB FUMARATEEQ 40MG BASETABLET / ORALRLD, RS2018-11-28

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N211349-00194874912030-07-28U-24562018-12-18
N211349-00189693362032-11-28Drug substance, Drug product2018-12-18
N211349-001107865002036-07-01Drug product2020-10-28
N211349-001119381302036-07-01Drug product2024-04-25
N211349-001119381312036-07-01Drug product2024-04-25
N211349-001119381322036-07-01Drug product2024-04-25
N211349-001119381332036-07-01Drug product2024-04-25
N211349-001119446202036-07-01Drug product2024-04-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2887673890dc5c…
2021-03-12 10:30 UTC2021-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283f01610625f2…
2019-09-15 20:21 UTC2019-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28b00525d2431f…
2019-07-19 19:46 UTC2019-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283f0d92c62455…
2023-05-13 08:27 UTC2023-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28053a50430f4f…
2023-01-26 05:58 UTC2023-01N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 5 · 194 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211349-00194874912030-07-28U-24562018-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-00189693362032-11-28Drug substance, Drug product2018-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001107865002036-07-01Drug product2020-10-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381302036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381312036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381322036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381332036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119446202036-07-01Drug product2024-04-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-00194874912030-07-28U-24562018-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-00189693362032-11-28Drug substance, Drug product2018-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001107865002036-07-01Drug product2020-10-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381302036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381312036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381322036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381332036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119446202036-07-01Drug product2024-04-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-00194874912030-07-28U-24562018-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-00189693362032-11-28Drug substance, Drug product2018-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001107865002036-07-01Drug product2020-10-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381302036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381312036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381322036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381332036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119446202036-07-01Drug product2024-04-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-00194874912030-07-28U-24562018-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-00189693362032-11-28Drug substance, Drug product2018-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001107865002036-07-01Drug product2020-10-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381302036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381312036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381322036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381332036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119446202036-07-01Drug product2024-04-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-00194874912030-07-28U-24562018-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-00189693362032-11-28Drug substance, Drug product2018-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001107865002036-07-01Drug product2020-10-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381302036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381312036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381322036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381332036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119446202036-07-01Drug product2024-04-25b8a1b40f171c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 63 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001ODE-2222025-11-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-001ODE-2222025-11-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001ODE-2222025-11-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001ODE-2222025-11-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211349-001ODE-2222025-11-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211349-001ODE-2222025-11-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211349-001ODE-2222025-11-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211349-001ODE-2222025-11-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211349-001ODE-2222025-11-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211349-001ODE-2222025-11-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211349-001ODE-2222025-11-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211349-001ODE-2222025-11-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211349-001ODE-2222025-11-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001NCE2023-11-285c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001ODE-2222025-11-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211349-001NCE2023-11-285d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N211349-001ODE-2222025-11-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211349-001NCE2023-11-284b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N211349-001ODE-2222025-11-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N211349-001NCE2023-11-2874a2ff9319b5…
2019-12-13 00:20 UTC2019-12N211349-001ODE-2222025-11-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N211349-001NCE2023-11-28bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N211349-001ODE-2222025-11-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211349-001NCE2023-11-28782e0a99824c…
2021-12-28 21:50 UTC2021-12N211349-001ODE-2222025-11-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001NCE2023-11-2887673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001ODE-2222025-11-2887673890dc5c…
2021-03-12 10:30 UTC2021-03N211349-001NCE2023-11-285aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N211349-001ODE-2222025-11-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211349-001NCE2023-11-288869cabd3fbd…
2020-12-22 03:56 UTC2020-12N211349-001ODE-2222025-11-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211349-001NCE2023-11-28c0c555d07b60…
2020-11-12 02:37 UTC2020-11N211349-001ODE-2222025-11-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12N211349-001NCE2023-11-283f01610625f2…
2019-12-14 00:12 UTC2019-12N211349-001ODE-2222025-11-283f01610625f2…
2019-09-15 20:21 UTC2019-09N211349-001NCE2023-11-28b00525d2431f…
2019-09-15 20:21 UTC2019-09N211349-001ODE-2222025-11-28b00525d2431f…
2019-07-19 19:46 UTC2019-07N211349-001NCE2023-11-28ea99ee380514…
2019-07-19 19:46 UTC2019-07N211349-001ODE-2222025-11-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211349-001ODE-2222025-11-286a51e52b5d6a…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XospataGILTERITINIBAstellas Pharma US, Inc.b5ff59aa-9c0d-49a8-9053-1f179b4823832022-01-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 211349
application number: NDA211349
ndc (product): 0469-1425

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 5 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0469-1425XospatagilteritinibAstellas Pharma US, Inc.NDACurrent
0469-1425XospatagilteritinibAstellas Pharma US, Inc.NDACurrent
0469-1425XospatagilteritinibAstellas Pharma US, Inc.NDACurrent
0469-1425XospatagilteritinibAstellas Pharma US, Inc.NDACurrent
0469-1425XospatagilteritinibAstellas Pharma US, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
69874SUPPL2022-01-13
69873SUPPL2022-01-13
69868SUPPL2022-01-13
64574SUPPL2020-09-14
58934SUPPL2019-06-04
58880SUPPL2019-05-30
58879SUPPL2019-05-30
56985ORIG2018-12-21
56610ORIG2018-11-30
56581ORIG2018-11-28