Application 211710

Type
NDA
Sponsor
BAYER HEALTHCARE

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001VITRAKVILAROTRECTINIB SULFATESOLUTION;ORALEQ 20MG BASE/MLYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N211710-001VITRAKVILAROTRECTINIB SULFATEEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26

Orange Book patents#

Current patent rows page 1 of 1 · 18 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N211710-001100057832029-10-21U-24722018-12-20
N211710-001100470972029-10-21U-24742018-12-20
N211710-001107740852029-10-21U-24702020-10-14
N211710-00188656982029-10-21U-24692018-12-20
N211710-00191270132029-10-21Drug substance, Drug product2018-12-20
N211710-00194471042029-10-21U-24702018-12-20
N211710-00196767832029-10-21U-24692018-12-20
N211710-00185132632029-12-23Drug substance, Drug product2018-12-20
N211710-001101728612035-11-16Drug substance2019-06-13
N211710-00197824142035-11-16U-24712018-12-20
N211710-001107995052036-08-15Drug substance2021-04-01
N211710-001100459912037-04-04U-24732018-12-20
N211710-001101371272037-04-04Drug product2018-12-20
N211710-001106680722037-04-04Drug product2020-09-17
N211710-001111917662037-04-04U-24712023-03-10
N211710-001114845352037-04-04U-24702023-03-10
N211710-001113379672037-05-16U-41232025-02-19
N211710-001119749982037-05-16U-41242025-02-19

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-2687673890dc5c…
2021-03-12 10:30 UTC2021-03N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-265aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-268869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26c0c555d07b60…
2019-12-14 00:12 UTC2019-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-263f01610625f2…
2019-09-15 20:21 UTC2019-09N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26b00525d2431f…
2019-07-19 19:46 UTC2019-07N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-263f0d92c62455…
2023-05-13 08:27 UTC2023-05N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26053a50430f4f…
2023-01-26 05:58 UTC2023-01N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N211710-001VITRAKVIEQ 20MG BASE/MLSOLUTION / ORALRLD, RS2018-11-26e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 16 · 633 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N211710-001100057832029-10-21U-24722018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001100470972029-10-21U-24742018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001107740852029-10-21U-24702020-10-14caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00188656982029-10-21U-24692018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00191270132029-10-21Drug substance, Drug product2018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00194471042029-10-21U-24702018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00196767832029-10-21U-24692018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00185132632029-12-23Drug substance, Drug product2018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001101728612035-11-16Drug substance2019-06-13caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-00197824142035-11-16U-24712018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001107995052036-08-15Drug substance2021-04-01caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001100459912037-04-04U-24732018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001101371272037-04-04Drug product2018-12-20caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001106680722037-04-04Drug product2020-09-17caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001111917662037-04-04U-24712023-03-10caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001114845352037-04-04U-24702023-03-10caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001113379672037-05-16U-41232025-02-19caaa826d4ba7…
2026-08-18 06:07:402026-07N211710-001119749982037-05-16U-41242025-02-19caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N211710-001100057832029-10-21U-24722018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001100470972029-10-21U-24742018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001107740852029-10-21U-24702020-10-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00188656982029-10-21U-24692018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00191270132029-10-21Drug substance, Drug product2018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00194471042029-10-21U-24702018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00196767832029-10-21U-24692018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00185132632029-12-23Drug substance, Drug product2018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001101728612035-11-16Drug substance2019-06-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-00197824142035-11-16U-24712018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001107995052036-08-15Drug substance2021-04-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001100459912037-04-04U-24732018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001101371272037-04-04Drug product2018-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001106680722037-04-04Drug product2020-09-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001111917662037-04-04U-24712023-03-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001114845352037-04-04U-24702023-03-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001113379672037-05-16U-41232025-02-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211710-001119749982037-05-16U-41242025-02-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001100057832029-10-21U-24722018-12-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001100470972029-10-21U-24742018-12-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001107740852029-10-21U-24702020-10-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-00188656982029-10-21U-24692018-12-2031067a03dcf5…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 4 · 141 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001ODE-2152025-11-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001ODE-2202025-11-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211710-001ODE-2212025-11-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08N211710-001ODE-2152025-11-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211710-001ODE-2202025-11-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211710-001ODE-2212025-11-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211710-001ODE-2152025-11-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211710-001ODE-2202025-11-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211710-001ODE-2212025-11-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211710-001ODE-2152025-11-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211710-001ODE-2202025-11-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211710-001ODE-2212025-11-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211710-001ODE-2152025-11-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211710-001ODE-2202025-11-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211710-001ODE-2212025-11-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211710-001ODE-2152025-11-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211710-001ODE-2202025-11-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211710-001ODE-2212025-11-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211710-001ODE-2152025-11-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211710-001ODE-2202025-11-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211710-001ODE-2212025-11-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211710-001ODE-2152025-11-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211710-001ODE-2202025-11-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211710-001ODE-2212025-11-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211710-001ODE-2152025-11-26d06236e962d9…
2024-10-29 15:01 UTC2024-10N211710-001ODE-2202025-11-26d06236e962d9…
2024-10-29 15:01 UTC2024-10N211710-001ODE-2212025-11-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211710-001ODE-2152025-11-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211710-001ODE-2202025-11-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211710-001ODE-2212025-11-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211710-001ODE-2152025-11-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211710-001ODE-2202025-11-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211710-001ODE-2212025-11-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211710-001ODE-2152025-11-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211710-001ODE-2202025-11-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211710-001ODE-2212025-11-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211710-001ODE-2152025-11-268072bd15b7f6…
2024-05-31 18:47 UTC2024-05N211710-001ODE-2202025-11-268072bd15b7f6…
2024-05-31 18:47 UTC2024-05N211710-001ODE-2212025-11-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211710-001NCE2023-11-265c6f7cd8ea54…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.0c8ca614-58b2-4aa4-83d3-0387a8f782fd2026-05-22Warnings, Adverse reactionsExact identifier
application applno (NDA): 211710
application number: NDA211710
ndc (product): 50419-392
ndc (product): 50419-393
VITRAKVILAROTRECTINIBLoxo Oncology, Inc.9525f887-a055-4e33-8e92-898d42828cd12018-12-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 211710
application number: NDA211710
ndc (product): 71777-392

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 10 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-392VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
50419-393VITRAKVILAROTRECTINIBBayer HealthCare Pharmaceuticals Inc.NDACurrent
71777-392VITRAKVILAROTRECTINIBLoxo Oncology, Inc.NDACurrent
71777-392VITRAKVILAROTRECTINIBLoxo Oncology, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82013SUPPL 2025-04-25
81925SUPPL 2025-04-16
76370SUPPL 2023-11-06
76369SUPPL 2023-11-06
72728SUPPL2022-11-28
72702SUPPL2022-11-25
66918SUPPL2021-03-30
66899SUPPL2021-03-29
66887SUPPL2021-03-26
66885SUPPL2021-03-26
56772ORIG2018-12-18
56702ORIG2018-12-11
56562ORIG2018-11-26