Application 211891

Type
ANDA
Sponsor
ALKEM LABS LTD

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001TOLVAPTANTOLVAPTANTABLET;ORAL30MGNoNo
002TOLVAPTANTOLVAPTANTABLET;ORAL60MGNoNo
003TOLVAPTANTOLVAPTANTABLET;ORAL15MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211891-001TOLVAPTANTOLVAPTAN30MGTABLET / ORALAB12020-05-19
A211891-002TOLVAPTANTOLVAPTAN60MGTABLET / ORAL2020-05-19
A211891-003TOLVAPTANTOLVAPTAN15MGTABLET / ORALAB12022-09-06

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A211891-001AB1
A211891-003AB1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 104 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211891-001TOLVAPTAN30MGTABLET / ORALAB12020-05-19caaa826d4ba7…
2026-08-18 06:07:402026-07A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19caaa826d4ba7…
2026-08-18 06:07:402026-07A211891-003TOLVAPTAN15MGTABLET / ORALAB12022-09-06caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211891-001TOLVAPTAN30MGTABLET / ORALAB12020-05-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211891-003TOLVAPTAN15MGTABLET / ORALAB12022-09-06011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211891-001TOLVAPTAN30MGTABLET / ORALAB12020-05-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211891-003TOLVAPTAN15MGTABLET / ORALAB12022-09-0631067a03dcf5…
2025-08-23 18:47 UTC2025-08A211891-001TOLVAPTAN30MGTABLET / ORALAB12020-05-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211891-003TOLVAPTAN15MGTABLET / ORALAB12022-09-066a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-06fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-06b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-0603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-062680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-065bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-06d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-19d06236e962d9…
2024-10-29 15:01 UTC2024-10A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19d06236e962d9…
2024-10-29 15:01 UTC2024-10A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-06d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-0679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211891-002TOLVAPTAN60MGTABLET / ORAL2020-05-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211891-003TOLVAPTAN15MGTABLET / ORALAB2022-09-06301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211891-001TOLVAPTAN30MGTABLET / ORALAB2020-05-191e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 70 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211891-001AB11caaa826d4ba7…
2026-08-18 06:07:402026-07A211891-003AB11caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211891-001AB11011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211891-003AB11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211891-001AB1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211891-003AB1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211891-001AB116a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211891-003AB116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211891-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211891-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211891-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211891-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211891-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211891-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211891-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211891-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211891-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211891-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211891-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211891-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211891-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211891-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211891-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211891-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211891-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211891-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211891-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211891-003AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211891-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A211891-003AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A211891-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A211891-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A211891-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A211891-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A211891-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A211891-001AB187673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A211891-002AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A211891-001AB15aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03A211891-002AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A211891-001AB18869cabd3fbd…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TolvaptanTOLVAPTANAscend Laboratories, LLCdd71ee70-9435-4715-bee5-edbb5a8d7d7b2022-09-07Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211891
application number: ANDA211891
ndc (product): 67877-635
ndc (product): 67877-636
ndc (product): 67877-637

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 9 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
67877-635TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-636TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-636TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-636TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-636TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-637TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-637TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-637TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent
67877-637TolvaptanTolvaptanAscend Laboratories, LLCANDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
62171ORIG2020-03-17